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Anti-Proliferative and Pro-Apoptotic Activities of 4-Methyl-2,6-bis(1-phenylethyl)phenol in Cancer Cells

Sung NY, Kim SC, Kim YH, Kim G, Lee Y, Sung GH, Kim JH, Yang WS, Kim MS, Baek KS, Kim JH, Cho JY

It has been found that 4-isopropyl-2,6-bis(1-phenylethyl)phenol (KTH-13), a novel compound isolated from Cordyceps bassiana, is able to suppress tumor cell proliferation by inducing apoptosis. To mass-produce this compound, we established...
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Women's Willingness to Pay for Cancer Screenin

Kwak MS, Sung NY, Yang JH, Park EC, Choi KS

  • KMID: 1078369
  • J Prev Med Public Health.
  • 2006 Jul;39(4):331-338.
OBJECTIVES: The goal of this study is to measure women's willingness to pay for cancer screening and to identify those factors associated with this willingness to pay METHODS: A population-based telephone...
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The Prevalence and Features of Korean Gout Patients Using the National Health Insurance Corporation Database

Lee CH, Sung NY

  • KMID: 2391935
  • J Rheum Dis.
  • 2011 Jun;18(2):94-100.
OBJECTIVE: We wanted to evaluate the prevalence of gout and its features in Korean people using the National Health Insurance Corporation (NHIC) database. METHODS: Using the NHIC database from 2001 to...
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Prognosis of endometriosis after surgical treatment in adolescents below 20 year age

Sung NY, Kim BS, Cho YJ, Choo YS, Kim JM, Yang SH

OBJECTIVE: To evaluate the clinical characteristics and prognosis of surgically treated endometriosis in adolescent women below 20 year age. METHODS: A retrospective review was conducted on patients diagnosed endometriosis on operation...
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Clinical Implications of Systemic Inflammatory Response Markers as Independent Prognostic Factors in Colorectal Cancer Patients

Paik KY, Lee IK, Lee YS, Sung NY, Kwon TS

  • KMID: 2167657
  • Cancer Res Treat.
  • 2014 Jan;46(1):65-73.
PURPOSE: Cancer-related inflammation affects many aspects of malignancy. We confirm the effects of early postoperative systemic inflammation on cancer prognosis. MATERIALS AND METHODS: Six hundred consecutive patients underwent surgery for colorectal...
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Participation Rate and Related Socio-demographic Factors in the National Cancer Screening Program

Sung NY, Park EC, Shin HR, Choi KS

  • KMID: 1747575
  • J Prev Med Public Health.
  • 2005 Feb;38(1):93-100.
BACKGROUND: Cancer is the leading cause of death and one of the largest burdens of disease in Korea. In 1996, the 'Ten year Plan for Cancer Control' was formulated and...
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In vitro fertilization outcomes in patients with advanced endometriosis after surgical treatment

Yang SH, Kim HO, Sung NY, Ahn HS, Choo YS, Yang KM, Song IO, Koong MK, Kang IS

OBJECTIVE: The aim of this study is to evaluate in vitro fertilization (IVF) outcomes in advanced endometriosis with/without surgical treatment and to compare between cyst enucleation and surgically treated peritoneal...
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Evaluation of satisfaction with three different cervical cancer screening modalities: clinician-collected Pap test vs. HPV test by self-sampling vs. HPV test by urine sampling

Shin HY, Lee B, Hwang SH, Lee DO, Sung NY, Park JY, Jun JK

OBJECTIVE: Human papillomavirus testing by self-sampling and urine sampling might be alternatives to Papanicolaou test (Pap test) for cervical cancer screening (CCS), and may increase compliance and adherence thereto. The...
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Factors Associated with Cancer Screening Participation, Korea

Kwak MS, Park EC, Bang JY, Sung NY, Lee JY, Choi KS

  • KMID: 792380
  • J Prev Med Public Health.
  • 2005 Nov;38(4):473-481.
OBJECTIVES: We wanted to identify those factors associated with stomach, colon, breast and cervix cancer screening. METHODS: A population-based telephone survey was conducted for 2 weeks (the 9th-23th of July,...
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Oral contraceptive pill pretreatment in ovarian stimulation with GnRH antagonists for in vitro fertilization: A comparative study

Choo YS, Han AR, Yang SH, Sung NY, Cha SH, Kim HO, Park CW, Song IO, Koong MK, Kang IS, Yang KM

OBJECTIVE: To evaluate whether oral contraceptive pill (OCP) pretreatments in gonadotropin-releasing hormone (GnRH) antagonist ovarian stimulation protocols takes positive effects on in vitro fertilization (IVF) outcomes in respect to retrieved...
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Inhibitory effect of ethanolic extract of Abeliophyllum distichum leaf on 3T3–L1 adipocyte differentiation

Thomas SS, Eom J, Sung NY, Kim DS, Cha YS, Kim KA

BACKGROUND/OBJECTIVES: Abeliophyllum distichum is a plant endemic to Korea, containing several beneficial natural compounds. This study investigated the effect of A. distichum leaf extract (ALE) on adipocyte differentiation. MATERIALS/METHODS: The cytotoxic...
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Influence of the Enhanced Recovery After Surgery Protocol on Postoperative Inflammation and Short-term Postoperative Surgical Outcomes After Colorectal Cancer Surgery

Jallounv HE, Lee IK, Kim MK, Sung NY, Turkistani SAA, Park SM, Won DY, Hong SH, Kye BH, Lee YS, Jeon HM

Purpose: Many studies have shown that the enhanced recovery after surgery (ERAS) protocols improve postoperative surgical outcomes. The purpose of this study was to observe the effects on postoperative inflammatory...
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Clinicopathological Analysis of Antibiotic Treatment after Appendectomy: A Randomized Prospective Trial

Lee IK, Kim HA, Kim YS, Oh ST, Jeun HM, Chang SK, Sung NY

  • KMID: 2004408
  • J Korean Surg Soc.
  • 2005 Mar;68(3):224-229.
PURPOSE: The optimal antibiotic regimen for appendicitis still remains poorly defined. The aim of this study was to define the optimal duration and route of antibiotics after an appendectomy, with...
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Budget Impact of the Accreditation Program for Clinical Laboratories on Colorectal Cancer Screening via Fecal Immunochemical Testing: Results from the National Cancer Screening Program in Korea

Jun JK, Sung NY, Song SH, Hong S, Jang MA, Song J, Kim JH, Min WK, Lee YK

BACKGROUND: False-positive fecal immunochemical test (FIT) results in the National Cancer Screening Program (NCSP) for colorectal cancer may lead to unnecessary procedures, such as colonoscopies, increasing the medical costs. We...
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Resistance of uterine radial artery blood flow is positively correlated with peripheral blood NK cell fraction in patients with unexplained recurrent spontaneous abortion

Koo HS, Yi HJ, Lee MY, Ahn HS, Choi MH, Sung NY, Hwang YI, Song IO, Koong MK, Kang IS, Yang KM

OBJECTIVE: To evaluate whether increased peripheral blood inflammatory immune cell can induce decrease of uterine blood flow in patients with unexplained recurrent spontaneous abortion (RSA). METHODS: This study designed prospectively 33...
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Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity

Sung NY, Kim MY, Cho JY

Flavonoids are plant pigments that have been demonstrated to exert various pharmacological effects including anti-cancer, anti-diabetic, anti-atherosclerotic, anti-bacterial, and anti-inflammatory activities. However, the molecular mechanisms in terms of exact target...
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Clinical Features of Hospitalized Adult Patients with Pneumonia in Novel Influenza A (H1N1) Infection

Han CH, Hyun YK, Choi YR, Sung NY, Park YS, Lee KS, Chung JH

  • KMID: 2319345
  • Tuberc Respir Dis.
  • 2010 Jul;69(1):24-30.
BACKGROUND: A novel 2009 influenza A (H1N1) virus emerged and disseminated to all over the world. There are few reports on the clinical characteristics of patients with complications. We describe...
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The Expression of Multiple Proteins as Prognostic Factors in Colorectal Cancer: Cathepsin D, p53, COX-2, Epidermal Growth Factor Receptor, C-erbB-2, and Ki-67

Shin IY, Sung NY, Lee YS, Kwon TS, Si Y, Lee YS, Oh ST, Lee IK

  • KMID: 1774523
  • Gut Liver.
  • 2014 Jan;8(1):13-23.
BACKGROUND/AIMS: A single gene mutation alone cannot explain the poor prognosis of colorectal cancer. This study aimed to establish a correlation between the expression of six proteins and the prognosis...
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Immunotoxicological Effects of Aripiprazole: In vivo and In vitro Studies

Baek KS, Ahn S, Lee J, Kim JH, Kim HG, Kim E, Kim JH, Sung NY, Yang S, Kim MS, Hong S, Kim JH, Cho JY

Aripiprazole (ARI) is a commonly prescribed medication used to treat schizophrenia and bipolar disorder. To date, there have been no studies regarding the molecular pathological and immunotoxicological profiling of aripiprazole....
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Immunomodulating activity of Sargassum horneri extracts in RAW264.7 macrophages

Kim DS, Sung NY, Park SY, Kim G, Eom J, Yoo JG, Seo IR, Han IJ, Cho YB, Kim KA

PURPOSE: Sargassum horneri (S. horneri) is a species of brown macroalgae that is common along the coast of Japan and Korea. The present study investigated the immuno-modulatory effects of different...
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