- Survival of Spiral Ganglion
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Cho CH
- KMID: 1978389
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Nov;52(11):869-873.
- doi: 10.3342/kjorl-hns.2009.52.11.869
Survival and regeneration of spiral ganglion neuron (SGN) following deafening carries critical implication for cochlear implantation as well as reinnervation of restored hair cells. Survival and development of SGN depend... -
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- Auditory brainstem response evoked by electrical stimulation (II): estimation of surviving spiral ganglion cells
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Sung MW, Kim CS
- KMID: 1684382
- Korean J Otolaryngol-Head Neck Surg.
- 1991 Dec;34(6):1154-1159.
No abstract available. -
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- Cochlear Implantation and Survival of Spiral Ganglion Neurons
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Lee IW
- KMID: 2141197
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2008 Jul;51(7):592-596.
No abstract available. -
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- Characteristics of the Dissociated Spiral Ganglion Cells from the Neonatal Rats by Immunohistochemical Staining
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Chung WH, Rho HI, Kim MS, Chang BC, Kim CH, Hong SH
- KMID: 1610872
- Korean J Otolaryngol-Head Neck Surg.
- 2002 May;45(5):433-438.
BACKGROUND AND OBJECTIVES: Neuronal dissociation culture is an important tool for the study of neuronal cell survival and apoptosis. To establish the culture methods, the cultured cells should be proved... -
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- Effect of Neurotrophins and Depolarization on Survival of Spiral Ganglion Neurons in Dissociation Cell Culture
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Kim MS, Chung WH, Cho YS, Shin DB, Bang EG, Lyoo SH, Hong SH
- KMID: 2275819
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Nov;44(11):1133-1139.
BACKGROUND AND OBJECTIVES: Several neurotrophic factors have been shown to play an essential trophic role in the development, maintenance and regulation of neuronal function. Specific neurotrophins are currently used in... -
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- Immunohistochemical Localization of Na/K-APTase Subunit Isoforms in Rat Inner Ear
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Kim HJ, Sohn JH, Lee SW, Kim BY, Ahn KY
- KMID: 2040103
- Korean J Anat.
- 1999 Aug;32(4):583-591.
The endolymph and perilymph of the inner ear have unique ionic composition and electrical potential. It is widely accepted that normal auditory function depends on them and Na/K-ATPase plays a... -
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- Damage of Spiral Ganglion Cell Induced by Ouabain Application in Cat
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Kim BY, Bae WY, Kim JR, Lee TH
- KMID: 1726625
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Sep;57(9):589-595.
- doi: 10.3342/kjorl-hns.2014.57.9.589
BACKGROUND AND OBJECTIVES: Auditory neuropathy is a hearing disorder characterized by the absence or the marked impairment of the auditory brainstem responses with the preservation of the cochlear microphonics (CMs)... -
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- Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis
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Gu TW, Bae WY, Park HT, Lee JH, Kang MY, Jeong SW, Shin YK
- KMID: 2278394
- Clin Exp Otorhinolaryngol.
- 2014 Mar;7(1):1-6.
OBJECTIVES: To examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis. METHODS: Cultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu... -
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- N-Acetylcysteine and N-Nitroarginine Methyl Ester Attenuate Carboplatin-Induced Ototoxicity in Dissociated Spiral Ganglion Neuron Cultures
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Moon IJ, Kim KR, Chu HS, Kim SH, Chung WH, Cho YS, Hong SH
- KMID: 2166455
- Clin Exp Otorhinolaryngol.
- 2011 Mar;4(1):11-17.
OBJECTIVES: Carboplatin, a platinum-containing anti-cancer drug used to treat a variety of cancers, induces ototoxicity. Since, reactive oxygen species (ROS) and nitric oxide (NO) seem to be responsible for this... -
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- Expression Patterns of Erythropoietin and Erythropoietin Receptor in the Spiral Ganglion of Guinea Pig after Noise Exposure
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Kim DH, Park JY, Kim AY, Choi JW, Han WK, Park YH
- KMID: 2276822
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2008 Jan;51(1):16-21.
BACKGROUND AND OBJECTIVES: Erythropoietin (EPO) is produced in the kidney and locally in the CNS and acts through binding to erythropoietin receptor (EPO-R). Apart from playing an essential role in... -
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- Expression of Neural Cell Adhesion Molecule and Polysialic Acid in Cultured Spiral Ganglion Neurons
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Park KH, Rask-Andersen H, Troy II FA, Park SN, Bae MY, Cho SJ, Lee HK, Kim JG, Son DW, Yeo SW
- KMID: 2074640
- Korean J Otolaryngol-Head Neck Surg.
- 2007 Jan;50(1):31-36.
BACKGROUND AND OBJECTIVES: Neural cell adhesion molecule (NCAM) and polysialic acid (PSA) function basically in cell adhesion and migration. In neural development, they are closely associated with axon pathfinding, synaptogenesis,... -
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- Regional Distribution of 5-HT 1A, 1B, and 1D Receptors in Rat Vestibular Nuclei (Vn) and Inner Ear
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Ahn SK, Balaban CD
- KMID: 2328942
- J Korean Bal Soc.
- 2008 Dec;7(2):228-228.
Migraine and anxiety disorders are frequently co-morbid with balance disorders. Potential mechanisms for migrainous vertigo include sites of action of 5-HT (serotonin) 1B and 1D receptor agonists such as rizatriptan,... -
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- Flow Cytometric Analysis of Cultured Adult Neural Stem Cells from Guinea Pig Spiral Ganglion
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Kim YH, Kim CH, Park KH, Park SN, Choi MY, Hong OK, Kim JH, Cho SJ, Kim JH, Chang KH, Yeo SW
- KMID: 2276985
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Feb;52(2):129-133.
- doi: 10.3342/kjorl-hns.2009.52.2.129
BACKGROUND AND OBJECTIVES: To make stem cell therapy successful as one of treatment options for sensorineural hearing loss, it is essential to culture and obtain sufficient amounts of adult neural... -
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- The Protective Effect of Egb 761 Against 3-Nitropropionic Acid-Induced Hearing Loss: The Role of Sirtuin 1
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Chang MY, Rhee J, Kim SH, Kim YH
- KMID: 2407786
- Clin Exp Otorhinolaryngol.
- 2018 Mar;11(1):9-16.
- doi: 10.21053/ceo.2017.00626
OBJECTIVES: Local administration of 3-nitropropionic acid (3-NP) to the inner ear induces sensorineural hearing loss. Several studies have shown the otoprotective effects of ginkgo biloba extract EGb 761. Moreover, EGb... -
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- The Presence of Neural Stem Cells and Changes in Stem Cell-Like Activity With Age in Mouse Spiral Ganglion Cells In Vivo and In Vitro
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Moon BS, Ammothumkandy A, Zhang N, Peng L, Ibrayeva A, Bay M, Pratap A, Park HJ, Bonaguidi , Lu W
- KMID: 2439848
- Clin Exp Otorhinolaryngol.
- 2018 Dec;11(4):224-232.
- doi: 10.21053/ceo.2018.00878
OBJECTIVES: Spiral ganglion neurons (SGNs) include potential endogenous progenitor populations for the regeneration of the peripheral auditory system. However, whether these populations are present in adult mice is largely unknown.... -
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- Immunohistochemical Expressions of TrkB and TrkC Receptors in Rat Cochleas with Amikacin-induced Ototoxicity
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Park SY, Chae SY
- KMID: 2274515
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Dec;41(12):1507-1512.
BACKGROUND AND OBJECTIVES: Neurotrophins have been known to be responsible for the differentiation and survival of developing neurons as well as for aiding the recovery of adult neurons from injury.... -
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- Developmental Analysis of Calretinin Using Quantitative Analysis in Rat Cochlea
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Kim YH, Park JY, Kim SM, Kim YS, Kim CS, Chang SO, Oh SH
- KMID: 2276384
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Apr;48(4):449-454.
BACKGROUND AND OBJECTIVES: Calretinin is a neuron specific, high affinity cytosolic calcium-binding protein of the EF-hand family. In the mammalian inner ear, it is expressed in the organ of Corti... -
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- Endogenous Stem Cells in the Ear
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Park KH
- KMID: 1798110
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 Dec;56(12):749-753.
- doi: 10.3342/kjorl-hns.2013.56.12.749
Basically stem cells have characteristics of multi-potency, differentiation into multiple tissue types, and self-renew through proliferation. Recent advances in stem cell biology can make identifying the stem-cell like cells in... -
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- Clinical Safety and Efficacy of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Sensorineural Hearing Loss Patients
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Lee HS, Kim WJ, Gong JS, Park KH
- KMID: 2415950
- J Audiol Otol.
- 2018 Apr;22(2):105-109.
- doi: 10.7874/jao.2017.00150
Stem cell transplantation represents a promising therapy for several degenerating and necrotic diseases. In several animal studies, we could find hearing restoration after inoculation of the mesenchymal stem cells' as... -
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- Comparison of Cochlear Morphology and Apoptosis in Mouse Models of Presbycusis
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Park SN, Back SA, Park KH, Kim DK, Park SY, Oh JH, Park YS, Yeo SW
- KMID: 2278608
- Clin Exp Otorhinolaryngol.
- 2010 Sep;3(3):126-135.
OBJECTIVES: Morphological studies on presbycusis, or age-related hearing loss, have been performed in several different strains of mice that demonstrate hearing loss with auditory pathology. The C57BL/6 (C57) mouse is... -
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