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A case of postoperative serotonin syndrome following the administration of fentanyl, palonosetron, and meperidine: A case report

Lee C, Kim EJ, Joe S, Ban JS, Lee JH, An JH

Serotonin syndrome is an unexpected adverse reaction of serotonergic medication. Some drugs used by anesthesiologists may cause serotonin syndrome. Serotonin syndrome is known to be related to 5-hydroxytryptamine 1A and...
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Management of Chemotherapy Induced Nausea and Vomiting

Song KH

  • KMID: 2263545
  • Korean J Med.
  • 2012 May;82(5):532-536.
Chemotherapy induced nausea and vomiting (CINV) is typically biphasic. The acute phase usually peaks in 5-6 hours after the administration of chemotherapeutic agents and the delayed phase can occur subsequently...
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Ramosetron might be useful for treating diabetic diarrhea with a rapid small bowel transit time

Lee TH, Lee JS

No abstract available.
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Diagnosis and Treatment of Functional Nausea and Vomiting

Shin JE

  • KMID: 2263547
  • Korean J Med.
  • 2012 May;82(5):543-548.
Functional nausea and vomiting is a broad term used to be described a subset of individuals who have chronic nausea and vomiting without apparent cause, despite extensive evaluation. According to...
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Mechanism of Interdigestive Migrating Motor Complex

Takahashi

  • KMID: 2325917
  • J Neurogastroenterol Motil.
  • 2012 Jul;18(3):246-257.
Migrating motor complex (MMC) is well characterized by the appearance of gastrointestinal contractions in the interdigestive state. This review article discussed the mechanism of gastrointestinal MMC. Luminal administration of 5-hydroxytryptamine...
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Pharmacotherapy of irritable bowel syndrome

Park CH, Han DS

Irritable bowel syndrome is a group of symptoms that includes abdominal pain and changes in the form and frequency of stool. Since its symptoms are usually long-lasting, the disease significantly...
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The comparative study to evaluate the effect of palonosetron monotherapy versus palonosetron with dexamethasone combination therapy for prevention of postoperative nausea and vomiting

Park JW, Jun JW, Lim YH, Lee SS, Yoo BH, Kim KM, Yon JH, Hong KH

BACKGROUND: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists are effective and safe on postoperative nausea and vomiting (PONV). Palonosetron, the newest 5-HT3 antagonist, has potent antiemetic property. We hypothesized that a...
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Palonosetron versus granisetron in combination with aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with gynecologic cancer

Fujiwara S, Terai Y, Tsunetoh S, Sasaki H, Kanemura M, Ohmichi M

OBJECTIVE: There is no research regarding the appropriate antiemetic agents for female patients, especially those receiving moderately emetogenic chemotherapy (MEC). We evaluated the antiemetic efficacy of a combination of 5-HT3...
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The Effect of Ondansetron on the Corrected QT Interval of Electrocardiography during General Anesthesia

Kim JI, Lee SK, Son JS, Ko SH

BACKGOUND: Prolongation of the corrected QT interval (QTc) has a potential risk of inducing life-threatening cardiac dysrhythmia. Although 5-HT3 antagonists are useful antiemetics, several cases of cardiac dysrhythmia after administration...
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Role of 5-Hydroxytryptamine in Non-Adrenergic Non-cholinergic Relaxation of the Circcular Muscle from Rat Stomach Fundus

Kim JH, Kang PJ, Kim CH, Cho SR, Lee IT, Park JH, Kim CH, Rhim BY

  • KMID: 2084756
  • Korean J Gastroenterol.
  • 1997 Oct;30(4):433-444.
BACKGROUND AND AIMS: Gastrointestinal smooth muscle is innervated bv non-adrenergic, non-cholinergic (NANC) inhibitory neurons. These inhibitory enteric neurons play an important role in gastrointestinal motility, and are involved in receptive...
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The Effect of Ondansetron on the Emergence Agitation after Sevoflurane Anesthesia in Pediatric Patients Undergoing Tonsillectomy

Lee KM, Kang DH, Lee SE, Kim YH, Lim SH, Lee JH, Cheong SH, Choe YK, Kim YJ, Shin CM

BACKGROUND: Emergence agitation is a common problem after sevoflurane anesthesia in children. Tropisetron, a 5-HT3 antagonist, significantly reduces the incidence of emergence agitation after sevoflurane anesthesia. This study evaluated the...
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Comparison of ramosetron's and ondansetron's preventive anti-emetic effects in highly susceptible patients undergoing abdominal hysterectomy

Lee JW, Park HJ, Choi J, Park SJ, Kang H, Kim EG

BACKGROUND: This study compared the preventive effects of ramosetron and ondansetron on postoperative nausea and vomiting (PONV) in highly susceptible patients undergoing abdominal hysterectomy. METHODS: In a prospective, randomized, double-blinded study,...
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Guidelines for the Treatment of Functional Dyspepsia

Jee SR, Jung HK, Min BH, Choi KD, Rhee PL, Kang YW, Lee SI, The Korean Society of Neurogastroenterology and Motility

Functional dyspepsia (FD) is defined as the presence of symptoms thought to originate in the gastroduodenal area, in the absence of any organic, systemic, or metabolic disease that is likely...
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