Korean J Med.  2012 May;82(5):543-548.

Diagnosis and Treatment of Functional Nausea and Vomiting

• Shin JE

Abstract

Functional nausea and vomiting is a broad term used to be described a subset of individuals who have chronic nausea and vomiting without apparent cause, despite extensive evaluation. According to the Rome III criteria, functional nausea and vomiting can be subdivided into three separate entities: chronic idiopathic nausea, functional vomiting and cyclic vomiting syndrome. Although no specific test can diagnose these diseases, the diagnostic approach requires excellent history taking combined with judicious diagnostic testing to exclude some organic cause of chronic nausea and vomiting. These conditions are probably not psychogenic in origin. Treatment remains empirical for all patients with functional nausea and vomiting. Reassurance and supportive physician-patient relationship, along with use of low-dose tricyclic antidepressants, can be beneficial in caring for patients with chronic idiopathic nausea and functional vomiting. The cornerstones of management for patients with cyclic vomiting syndrome are identifying and avoidance of triggering factors, treatment with prophylactic antimigraine agents, 5-HT3 antagonists, benzodiazepines and 5-HT1 agonists (sumatriptan), with supportive therapy.

Keyword

Functional nausea; Functional vomiting; Cyclic vomiting syndrome

MeSH Terms

Antidepressive Agents, Tricyclic
Benzodiazepines
Diagnostic Tests, Routine
Humans
Nausea
Rome
Serotonin 5-HT1 Receptor Agonists
Serotonin 5-HT3 Receptor Antagonists
Vomiting
Antidepressive Agents, Tricyclic
Benzodiazepines
Serotonin 5-HT1 Receptor Agonists
Serotonin 5-HT3 Receptor Antagonists
Vomiting