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Molecular Motor Proteins of the Kinesin Superfamily Proteins (KIFs): Structure, Cargo and Disease

Seog DH, Lee DH, Lee SK

Intracellular organelle transport is essential for morphogenesis and functioning of the cell. Kinesins and kinesin-related proteins make up a large superfamily of molecular motors that transport cargoes such as vesicles,...
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Neuromolecular Etiology of Bipolar Disorder: Possible Therapeutic Targets of Mood Stabilizers

Lee JG, Woo YS, Park SW, Seog DH, Seo MK, Bahk WM

Bipolar disorder is a mental illness that causes extreme mood swings and has a chronic course. However, the mechanism by which mood episodes with completely opposite characteristics appear repeatedly, or...
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Sorting Nexin 17 Interacts Directly with Kinesin Superfamily KIF1B beta Protein

Seog DH, Han J

KIF1B beta is a member of the Kinesin superfamily proteins (KIFs), which are microtubule-dependent molecular motors that are involved in various intracellular organellar transport processes. KIF1B beta is not restricted...
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Cloning of a pore-forming subunit of ATP-sensitive potassium channel from Clonorchis sinensis

Hwang SY, Han HJ, Kim SH, Park SG, Seog DH, Kim NR, Han J, Chung JY, Kho WG

A complete cDNA sequence encoding a pore-forming subunit (Kir6.2) of ATP-senstive potassium channel in the adult worm, Clonorchis sinensis, termed CsKir6.2, was isolated from an adult cDNA library. The cDNA...
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Kinesin Superfamily KIF1A Protein Binds to Synaptotagmin XI

Park HY, Yea SS, Jang WH, Chung JY, Lee SK, Kim SJ, Yang YI, Kim JY, Park YH, Seog DH

  • KMID: 2092858
  • Korean J Anat.
  • 2005 Oct;38(5):403-411.
The kinesin proteins (KIFs) make up a large superfamily of molecular motors that transport cargo such as vesicles, protein complexes, and organelles. KIF1A is a monomeric motor that conveys synaptic vesicle...
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Kinesin Superfamily KIF1Balpha Protein Binds to the PDZ Domain of MALS-3

Kim SJ, Lee CH, Park HY, Yea SS, Jang WH, Lee SK, Park YH, Jung Y, Seog DH

  • KMID: 2092879
  • Korean J Anat.
  • 2006 Oct;39(5):375-382.
The Kinesin superfamily proteins (KIFs) make up a large superfamily of molecular motors that transport cargo such as vesicles, protein complexes, and organelles. KIF1Balpha is a monomeric motor that conveys mitochondria and...
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Kinesin Superfamily KIF5 Proteins Bind to betaIII Spectrin

Paik JE, Kim N, Yea SS, Jang WH, Chung JY, Lee SK, Park YH, Han J, Seog DH

  • KMID: 2285302
  • Korean J Physiol Pharmacol.
  • 2004 Jun;8(3):167-172.
The kinesin proteins (KIFs) make up a large superfamily of molecular motors that transport cargo such as vesicles, protein complexes, and organelles. KIF5 is a heterotetrameric motor that conveys vesicles...
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Neuronal activation increases the density of eukaryotic translation initiation factor 4E mRNA clusters in dendrites of cultured hippocampal neurons

Moon IS, Cho SJ, Seog DH, Walikonis

Activity-dependent dendritic translation in CNS neurons is important for the synapse-specific provision of proteins that may be necessary for strengthening of synaptic connections. A major rate-limiting factor during protein synthesis...
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N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points

Islam MA, Sharif SR, Lee H, Seog DH, Moon IS

N-acetylglucosamine kinase (GlcNAc kinase or NAGK) is a ubiquitously expressed enzyme in mammalian cells. Recent studies have shown that NAGK has an essential structural, non-enzymatic role in the upregulation of...
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Definition of the peptide mimotope of cellular receptor for hepatitis C virus E2 protein using random peptide library

Lee IH, Paik JE, Seol SY, Seog DH, Park SG, choi IH

BACKGROUND: Hepatitis C virus(HCV), a family of Flaviviridae, has a host cell-derived envelope containing a positive-stranded RNA genome, and has been known as the maj or etiological agent for chronic...
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