Clin Psychopharmacol Neurosci.
2022 May;20(2):228-239. 10.9758/cpn.2022.20.2.228.
Neuromolecular Etiology of Bipolar Disorder: Possible Therapeutic Targets of Mood Stabilizers
- Affiliations
-
- 1Department of Psychiatry, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
- 2Paik Institute for Clinical Research, Inje University, Busan, Korea.
- 3Department of Health Science and Technology, Graduate School, Inje University, Busan, Korea.
- 4Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- 5Department of Convergence Biomedical Science, Inje University College of Medicine, Busan, Korea.
- 6Department of Biochemistry, Inje University College of Medicine, Busan, Korea.
- 7Dementia and Neurodegenerative Disease Research Center, Inje University College of Medicine, Busan, Korea.
- KMID: 2530452
- DOI: http://doi.org/10.9758/cpn.2022.20.2.228
Abstract
- Bipolar disorder is a mental illness that causes extreme mood swings and has a chronic course. However, the mechanism by which mood episodes with completely opposite characteristics appear repeatedly, or a mixture of symptoms appears, in patients with bipolar disorder remains unknown. Therefore, mood stabilizers are indicated only for single mood episodes, such as manic episodes and depressive episodes, and no true mood-stabilizing drugs effective for treating both manic and depressive episodes currently exist. Therefore, in this review, therapeutic targets that facilitate the development of mood stabilizers were examined by reviewing the current understanding of the neuromolecular etiology of bipolar disorder.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Trends in Pharmacotherapy of the Hospitalized Patients with Bipolar Disorder: A Twele-year Naturalistic Study
- Drug-Drug Interactions: Mood Stabilizers and Anti-Anxiety Drugs
- Pharmacological Treatment Strategies for Acute Bipolar Depression
- A Trend of Drug Use in Inpatients with Bipolar Disorder: A 4-Year Naturalistic Study in One Hospital
- The Use of Atypical Antipsychotics in Bipolar Disorder
