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Brown Adipose Tissue as a Therapeutic Target for Obesity: From Mice to Humans

Saito M

Brown adipose tissue (BAT) is a site of sympathetically activated non-shivering thermognenesis during cold exposure and after spontaneous hyperphagia, thereby involving in the autonomic regulation of energy balance and body...
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Antiplatelet Therapy May Be Insufficient to Prevent Stroke Recurrence Before Percutaneous Patent Foramen Ovale Closure

Kawano H, Honda Y, Johno T, Maruoka H, Nakanishi K, Saito M, Ogata K, Yamamichi A, Kawatake A, Hirano T

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Brown Adipose Tissue as a Regulator of Energy Expenditure and Body Fat in Humans

Saito M

Brown adipose tissue (BAT) is recognized as the major site of sympathetically activated nonshivering thermogenesis during cold exposure and after spontaneous hyperphagia, thereby controling whole-body energy expenditure and body fat....
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School-aged asthma children with high fractional exhaled nitric oxide levels and lung dysfunction are at high risk of prolonged lung dysfunction

Saito M, Kikuchi Y, Lefor AK

BACKGROUND: Long-term management of bronchial asthma based on the fractional exhaled nitric oxide (FeNO) value alone is not conclusive yet. Therefore, we combined FeNO testing and spirometry, a commonly used...
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Computerized EEG and Neuropsychopharmacology

Saito M

  • KMID: 2286994
  • Korean J Psychopharmacol.
  • 1997 Apr;8(1):55-59.
In parallel to rapid popularization of personal computers, EEG studies in psychiatric field have become one of important and indispensable methods particularly because of appearance of topographical imaging of scalp...
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Brown Fat as a Regulator of Systemic Metabolism beyond Thermogenesis

Yuko OO, Saito M

Brown adipose tissue (BAT) is a specialized tissue for nonshivering thermogenesis to dissipate energy as heat. Although BAT research has long been limited mostly in small rodents, the rediscovery of...
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Thermogenic Brown Fat in Humans: Implications in Energy Homeostasis, Obesity and Metabolic Disorders

Saito M, Okamatsu-Ogura Y

In mammals including humans, there are two types of adipose tissue, white and brown adipose tissues (BATs). White adipose tissue is the primary site of energy storage, while BAT is...
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Nucleotide sequence analysis of HTLV-I isolate from a Korean patient with HAM/TSP

Saito M, Moritoyo T, Park JH, Lee BI, Kim JS, Fujisawa J, Osame M, Yoshida M

Limited nucleotide sequences of human T-cell lymphotropic virus type I (HTLV-1) provirus isolated from the first case of a Korean patient with HTLV-I associated myelopathy and tropical spastic paraparesis (HAM/TSP)...
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Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer

Yamashita , Suzuki R, Kubo T, Onodera K, Iida T, Saito M, Arimura Y, Endo T, Nojima M, Nakase H

BACKGROUND/AIMS: Fundic gland polyps (FGPs), hyperplastic polyps (HPs), and xanthomas (XTs) are common benign gastric lesions that can be diagnosed by endoscopic appearance alone in most cases. The aim of...
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Differential diagnosis between intraductal papillary mucinous neoplasm with an associated invasive carcinoma and pancreatic ductal adenocarcinoma on ultrasonography: the utility of echo intensity and contrast enhancement

Saito M, Hirokawa N, Usami Y, Someya M, Sakata KI

PURPOSE: The aim of this study was to investigate the utility of echo intensity and contrast enhancement in the differential diagnosis between intraductal papillary mucinous neoplasm with an associated invasive...
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Efficacy of edoxaban for the treatment of gynecological cancer-associated venous thromboembolism: analysis of Japanese real-world data

Odajima S, Seki T, Kato S, Tomita K, Shoburu Y, Suzuki E, Takenaka M, Saito M, Takano H, Yamada K, Okamoto A

Objective Direct oral anticoagulants (DOACs) are increasingly being used for the treatment of cancer-associated venous thromboembolism (CAT). However, there is limited evidence of the efficacy of DOACs for the treatment of...
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Tumor volume and lymphovascular space invasion as a prognostic factor in early invasive adenocarcinoma of the cervix

Murakami I, Fujii T, Kameyama K, Iwata T, Saito M, Kubushiro , Aoki D

OBJECTIVE: The aim of this study was to investigate the risk and recurrence of early invasive adenocarcinoma of the cervix, and to determine whether non-radical methods of management could be...
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p16INK4a immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: comparison study with HPV genotyping

Nishio S, Fujii T, Nishio H, Kameyama K, Saito M, Iwata T, Kubushiro , Aoki D

OBJECTIVE: In cervical intraepithelial neoplasia (CIN), p16INK4a immunohistochemistry has been reported to be a useful diagnostic biomarker. However, limited information is available about the association between the p16INK4a immunohistochemistry and...
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