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Pharmacological treatment options for acne

Park KY

Acne vulgaris is a very common condition affecting up of about 80% to 90% of adolescents. The patients with acne have been shown to be adversely impacted by the effect...
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Comparison of the Efficacy of Systemic Antibiotics and Systemic Retinoids in Hidradenitis Suppurativa

Seol JE, Park SH, Jung SY, Hwang SH, Wang HY, Kim H, Seo JK, Park IH

  • KMID: 2401251
  • Korean J Dermatol.
  • 2017 Dec;55(10):651-656.
BACKGROUND: Hidradenitis suppurativa is a chronic inflammatory skin disease showing recurrent painful nodules and abscesses. Many treatment modalities, such as topical antibiotics, systemic antibiotics, retinoids, immunomodulators, biologics, and surgical treatment...
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Lung Regeneration Therapy for Chronic Obstructive Pulmonary Disease

Oh DK, Kim YS, Oh YM

Chronic obstructive pulmonary disease (COPD) is a critical condition with high morbidity and mortality. Although several medications are available, there are no definite treatments. However, recent advances in the understanding...
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Genetic Risk Factors for Psoriasis in Turkish Population: -1540 C/A, -1512 Ins18, and +405 C/G Polymorphisms within the Vascular Endothelial Growth Factor Gene

Bozduman T, Ersoy Evans S, Karahan S, Hayran Y, Akbiyik F, Lay I

BACKGROUND: Evidence regarding the vascular endothelial growth factor A (VEGFA) as a potent mediator of angiogenesis and inflammation in psoriasis has revealed variations in this gene as surrogate markers of...
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The Effect of Metformin Treatment on CRBP-I Level and Cancer Development in the Liver of HBx Transgenic Mice

Kim JH, Alam MM, Park DB, Cho M, Lee SH, Jeon YJ, Yu DY, Kim TD, Kim HY, Cho CG, Lee DH

Retinoids regulate not only various cell functions including proliferation and differentiation but also glucose and lipid metabolism. After we observed a marked up-regulation of cellular retinol-binding protein-I (CRBP-I) in the...
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Retinoid Metabolism and Diabetes Mellitus

Rhee EJ, Plutzky J

Retinoid acid is a metabolite of vitamin A and functions as an important factor in cell survival, differentiation and death. Most previous studies on retinoid metabolism have focused on its...
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Pityriasis Rubra Pilaris Treated with Infliximab

Choi JS, Kim JH, Yun JH, Kang HK, Baek JO, Lee JR, Roh JY

  • KMID: 2302402
  • Korean J Dermatol.
  • 2012 Nov;50(11):982-986.
Pityriasis rubra pilaris (PRP) is a chronic papulosquamous disorder of unknown etiology, which may pose therapeutic challenges. There is currently no universally effective treatment for PRP, and some cases are...
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Radical Surgical Excision and Use of Lateral Thoracic Flap for Intractable Axillary Hidradenitis Suppurativa

Teo WL, Ong YS, Tan BK

Current treatments for hidradenitis suppurativa (HS) include prolonged courses of antibiotics, retinoids, immunosuppressants, and biologics. Severe cases that are resistant to prolonged medical treatment pose a therapeutic challenge. We propose...
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Pityriasis Rotunda Treated with Combination of Topical and Oral Retinoid

Kim HW, Park HC, Roh HS, Kim JE, Ko JY, Ro YS

  • KMID: 2088505
  • Korean J Dermatol.
  • 2012 Oct;50(10):917-920.
Pityriasis rotunda (PR) is a rare disease characterized by persistent, sharply defined, oval, scaly patches of dry skin, localized mainly on the trunk and extremities. Its etiology remains unknown. However,...
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A Case of Acrodermatitis Continua of Hallopeau Treated with Etanercept

Park J, Lee Y, Noh S, Cho S, Park CO, Lee KH

  • KMID: 2247517
  • Korean J Dermatol.
  • 2012 Jan;50(1):92-94.
Acrodermatitis continua of Hallopeau (ACH) is a rare form of acropustular eruption characterized by a presence of aseptic pustules on inflammatory periungual or subungual regions. Frequently accompanied by paronychia, atrophic...
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A Case of Interstitial Pneumonitis Induced by Acitretin

Kim SD, Kim YJ, Ko SC, Lee HJ, Choi JP, Lee H, Kim S

  • KMID: 2258885
  • Korean J Med.
  • 2011 Jun;80(Suppl 2):S183-S187.
Retinoids are effective systemic agents in the treatment of psoriasis. Acitretin, a synthetic aromatic derivative of retinoic acid, has replaced etretinate in retinoid therapy of psoriasis because of its more...
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Lymphohematopoietic Cancer Mortality and Morbidity of Workers in a Refinery/Petrochemical Complex in Korea

Koh DH, Kim TW, Yoon YH, Shin KS, Yoo SW

  • KMID: 2316997
  • Saf Health Work.
  • 2011 Mar;2(1):26-33.
OBJECTIVES: The purpose of this retrospective cohort study was to investigate the relationship between exposure of Korean workers to petrochemicals in the refinery/petrochemical industry and lymphohematopoietic cancers. METHODS: The cohort consisted...
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Retinoid Induces the Degradation of Corneodesmosomes and Downregulation of Corneodesmosomal Cadherins: Implications on the Mechanism of Retinoid-induced Desquamation

Kim MY, Lee SE, Chang JY, Kim SC

  • KMID: 2383243
  • Ann Dermatol.
  • 2011 Nov;23(4):439-447.
BACKGROUND: Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE: The aim of this study...
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A Case of Recalcitrant Hidradenitis Suppurativa Treated with Secondary Healing and a Split Thickness Skin Graft after Exteriorization

Suh KS, Baek JW, Kang DY, Kang JS, Kim TK, Jeon YS, Park JH, Kim ST

  • KMID: 2088085
  • Korean J Dermatol.
  • 2010 Sep;48(9):799-803.
Hidradenitis Suppurativa (HS) is a chronic relapsing disease that involves the apocrine gland-bearing skin. It results in sinus tract formation, fibrosis and scarring. Many different treatments for HS have been...
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Pharmacologic Treatment of Acne

Suh DH

Acne is one of the most common skin diseases. It usually occurs during adolescence, but can persist into middle age. The most deleterious form can result in permanent scarring on...
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Successful Treatment of Steatocystoma Multiplex with OK-432 Sclerotherapy

Park SY, Nam HM, Park K, Park SD

  • KMID: 2247700
  • Korean J Dermatol.
  • 2010 Jun;48(6):529-532.
Steatocystoma multiplex is a hamartomatous malformation of the pilosebaceous junction and this manifests as multiple, asymptomatic, yellowish or skin-colored cystic papules and nodules located most commonly on the upper anterior...
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A Case of Impetigo Herpetiformis Treated with Cyclosporine

Cho EB, Choi WJ, Seung NR, Park EJ, Cho HJ, Kim KH, Kim KJ

  • KMID: 1454998
  • Korean J Dermatol.
  • 2010 May;48(5):420-423.
Impetigo herpetiformis is a rare, severe dermatologic disorder that is similar to a type of pustular psoriasis that predominantly occurs during the 3rd trimester of pregnancy. This condition usually resolves...
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Effects of all-trans retinoic acid on expression of Toll-like receptor 5 on immune cells

Kim KH, Park SJ

  • KMID: 2328585
  • J Korean Assoc Oral Maxillofac Surg.
  • 2010 Dec;36(6):481-489.
INTRODUCTION: TLR-5, a member of the toll-like receptor (TLR) family, is a element of the type I transmembrane receptors, which are characterized by an intracellular signaling domain homolog to the...
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Two Cases of Papillon-Lefevre Syndrome

Cho HH, Kim SH, Seo SH, Jung DS, Ko HC, Kim MB, Kwon KS

  • KMID: 2247930
  • Korean J Dermatol.
  • 2009 Apr;47(4):472-478.
Papillon-Lefevre syndrome is an extremely rare genodermatosis characterized by palmoplantar keratoderma and premature loss of teeth. It is inherited as an autosomal recessive trait, and is known to be caused...
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Stellate ganglion block for the treatment of acne vulgaris in adult : Case reports

Ko HC, Ko DH, Shinn HK, Song JH, Lee HS, Cha YD

  • KMID: 2263362
  • Anesth Pain Med.
  • 2009 Jan;4(1):71-74.
Therapeutic agents such as antibiotics, hormonal drugs and retinoids are usually applied for the treatment of acne vulgaris. Adult patients with acne vulgaris may suffer from various side effects of...
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