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Circulation remodeling after flow diversion of an anterior communicating artery aneurysm: A case report

Withers J, Regenhardt RW, Dmytriw AA, Vranic JE, Marciano R, Rabinov JD

Anterior communicating artery aneurysms are the most common intracranial aneurysm and have a high risk of rupture which can lead to morbidity and mortality. Traditionally, intracranial aneurysms were treated by...
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Symptomatic perianeursymal cyst development 20 years after endovascular treatment of a ruptured giant aneurysm: Case report and updated review

Wang AJ, Vranic JE, Regenhardt RW, Dmytriw AA, Lee CK, Sadegh C, Rabinov JD, Stapleton CJ

Perianeurysmal cysts are a rare and poorly understood finding in patients both with treated and untreated aneurysms. While the prior literature suggests that a minority of perianeurysmal cysts develop 1-4...
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Deconstructive repair of a traumatic vertebrovertebral arteriovenous fistula via a contralateral endovascular approach

Nageshwaran SK, Deng F, Regenhardt RW, Das AS, Alotaibi NM, Patel AB, Stapleton CJ

Vertebrovertebral arteriovenous fistulas (VVAVFs) are rare entities that lack consensus guidelines for their management. Our case describes the successful treatment of a traumatic VVAVF via a contralateral deconstructive endovascular approach....
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Replacing Alteplase with Tenecteplase: Is the Time Ripe?

Singh N, Menon BK, Dmytriw AA, Regenhardt RW, Hirsch JA, Ganesh A

Thrombolysis for acute ischemic stroke has predominantly been with alteplase for over a quarter of a century. In recent years, with trials showing evidence of higher rates of successful reperfusion,...
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Asymptomatic Cerebral Small Vessel Disease: Insights from Population-Based Studies

Das AS, Regenhardt RW, Vernooij M, Blacker D, Charidimou A, Viswanathan A

Cerebral small vessel disease (CSVD) is a common group of neurological conditions that confer a significant burden of morbidity and mortality worldwide. In most cases, CSVD is only recognized in...
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Management of Adult Unruptured Brain Arteriovenous Malformations: An Updated Network Meta-Analysis

Dmytriw AA, Ku J, Ghozy S, Grewal S, Cancelliere NM, Azzam AY, Regenhardt RW, Rabinov JD, Stapleton CJ, Patel K, Patel AB, Pereira VM, Tymianski M

The management of unruptured brain arteriovenous malformations (ubAVMs) is a complex challenge to neurovascular practitioners. This meta-analysis aimed to identify the optimal management of ubAVMs comparing conservative management, embolization, radiosurgery,...
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Intracranial stenting compared to medical treatment alone for intracranial atherosclerosis patients: An updated meta-analysis

Dmytriw AA, Ku J, Azzam AY, Elamin O, Cancelliere N, Kapadia A, Rabinov JD, Stapleton CJ, Regenhardt RW, Pereira VM, Patel AB, Yang VX

Objective: Stroke is the second-leading cause of death globally. Intracranial atherosclerotic stenosis (ICAS) represents 10-15% of ischemic strokes in Western countries and up to 47% in Asian countries. Patients with...
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Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study

Salim HA, Yedavalli V, Musmar B, Adeeb N, Essibayi MA, Naamani KE, Henninger N, Sundararajan SH, Kühn AL, Khalife J, Ghozy S, Scarcia L, Tan BY, Pulli B, Heit JJ, Regenhardt RW, Cancelliere NM, Bernstock JD, Rouchaud A, Fiehler J, Sheth S, Puri AS, Dyzmann C, Colasurdo M, Barreau X, Renieri L, Filipe JP, Harker P, Radu RA, Marotta TR, Spears J, Ota T, Mowla A, Jabbour P, Biswas A, Clarençon F, Siegler JE, Nguyen TN, Varela R, Baker A, Altschul D, Gonzalez NR, Möhlenbruch MA, Costalat V, Gory B, Stracke CP, Aziz-Sultan MA, Hecker C, Shaikh H, Liebeskind DS, Pedicelli A, Alexandre AM, Tancredi I, Faizy TD, Kalsoum E, Lubicz B, Patel AB, Pereira VM, Guenego A, Dmytriw AA, the MAD MT Investigators

Background and Purpose The management of acute ischemic stroke (AIS) due to distal medium vessel occlusion (DMVO) remains uncertain, particularly in comparing the effectiveness of intravenous thrombolysis (IVT) plus mechanical...
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