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How to Do Random Allocation (Randomization)

Kim J, Shin W

PURPOSE: To explain the concept and procedure of random allocation as used in a randomized controlled study. METHODS: We explain the general concept of random allocation and demonstrate how to perform...
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Random allocation and dynamic allocation randomization

Kang H

Random allocation is commonly used in medical researches, and has become an essential part of designing clinical trials. It produces comparable groups with regard to known or unknown prognostic factors,...
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Randomization in clinical studies

Lim CY, In J

Randomized controlled trial is widely accepted as the best design for evaluating the efficacy of a new treatment because of the advantages of randomization (random allocation). Randomization eliminates accidental bias,...
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The Quality of Reporting of Randomized Controlled Trials in Korean Medical Journals Indexed in KoreaMed: Survey of Items of the Revised CONSORT Statement

Hwang YW, Lee KW, Hwang IH, Kim SY

  • KMID: 2294451
  • J Korean Acad Fam Med.
  • 2008 Apr;29(4):276-282.
BACKGROUND: The revised Consolidated Standards for Reporting of Trials (CONSORT) were developed to improve the reporting of Randomized Controlled Trials. We studied to survey the extent to which RCTs report...
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Quality Assessment of Randomized Controlled Trials Published in the Korean Journal of Urology Over the Past 20 Years

Lee JY, Chung JH, Kang DH, Lee JW, Moon HS, Yoo TK, Choi HY, Lee SW

  • KMID: 2315430
  • Korean J Urol.
  • 2011 Sep;52(9):642-646.
PURPOSE: Because low-quality trials may lead to erroneous conclusions, quality assessments are necessary. Thus, in this study, we scrutinized randomized controlled trials (RCTs) published in the Korean Journal of Urology...
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Randomization, What is the Proper Method?

Hong JH, Yoo JC

  • KMID: 2049400
  • Clin Should Elbow.
  • 2013 Jun;16(1):58-62.
PURPOSE: Among the numerous clinical researches and following articles, there are few cases that apply proper methodology, which guarantees high reliability. By understanding the right concept and randomization of proper...
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A Quality Analysis of Randomized Controlled Trials about Erectile Dysfunction

Chung JH, Lee JW, Jo JK, Kim KS, Lee SW

  • KMID: 2320844
  • World J Mens Health.
  • 2013 Aug;31(2):157-162.
PURPOSE: A low quality clinical trial could produce errors, and these errors could, in turn, distort the results of the clinical trial. To avoid applying distorted results of trials clinically,...
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Onset and Duration of Succinylcholine and Vecuronium Neuromuscular Blockade at Laryngeal Adductor and Adductor Pollicis Muscles

Hwang SO, Kim SK, Park NH

Adequate relaxation of the laryngeal adductor muscle is required to obtain good tracheal intubating condition. But we couldnt check rountinely laryngeal adductor muscle response, so we quantify the effects of...
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Effect of supplemental intravenous anesthesia in plastic surgery under local anesthesia

Lee TS, Bang SI, Kang H

  • KMID: 2119353
  • J Korean Soc Plast Reconstr Surg.
  • 1998 Jan;25(1):54-59.
When operations in the field of plastic surgery are performed under local anesthesia, the degree of pain suffering the patients becomes different depending on the kind, dosage effective duration of...
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Day 3 Trasfer Program in In Vitro Fertilization and Embryo Transfer

Moon SY, Choi YM, Kim SH, Oh SK, Suh CS, Lee JY, Jung BJ, Kim HS, Ryu BY, Kim JG, Jee BC, Oh SY

  • KMID: 2261349
  • Korean J Obstet Gynecol.
  • 1999 Mar;42(3):457-463.
OBJECTIVE: To investigate the positive or negative effect of delaying embryo transfer(ET) one day in IVF-ET. METHODS: From May to July, 1997, a total of 64 patients was emolled in...
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Introduction of a pilot study

In J

A pilot study asks whether something can be done, should the researchers proceed with it, and if so, how. However, a pilot study also has a specific design feature; it...
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An introduction to propensity score matching methods

Lee DK

Propensity score matching method (PSM) is widely used in observational study to reduce selection bias. Observational study lacks randomization, hence, statistical inferences without bias adjustments usually include observed or unobserved...
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A Planned Prospective, Randomized, Placebo-Controlled Multicenter Trial Assessing the Effect of Helicobacter pylori Eradication on the Healing of Iatrogenic Ulcer after Endoscopic Resection of Gastric Neoplasm

Kim SG, Song HJ, Choi IJ, Cho JY, Jung HY, Keum B, Cheon JH, Lee YC, Kim JG, Park SK, Park BJ, Jung HC

  • KMID: 2167259
  • Gut Liver.
  • 2010 Dec;4(4):514-517.
BACKGROUND/AIMS: Helicobacter pylori eradication may facilitate the healing of iatrogenic ulcer after endoscopic resection of gastric neoplasm. This study involved designing a randomized, double-blinded, placebo-controlled, multicenter trial, performed by the...
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The Effect of Itopride, a New Prokinetic, on Acid Reflux Symptoms and Variables in Patients with GERD

Choi SC, Kim TH, Kim HS, Im CJ, Yoo KS, Sohn YW, Yeom JJ, Kim YS, Kim SW, Seo GS, Nah YH

  • KMID: 2304953
  • Korean J Gastrointest Motil.
  • 2003 Jun;9(1):6-11.
BACKGROUND/AIMS: Itopride is a newly developed prokinetic agent enhancing gastric motility through both antidopaminergic and anti-acetylcholinesterase actions. The importance of esophageal motor dysfunction in the pathogenesis of gastro-esophageal reflux disease...
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Recent trend of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) management

Lee SW

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition. However, many of the traditional therapies like monotherapy used in clinical practice fail to show efficacy. There is no one...
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Serum interferon-gamma and interleukins-6 and -8 during infection with Fasciola gigantica in cattle and buffaloes

Molina EC

  • KMID: 1114854
  • J Vet Sci.
  • 2005 Jun;6(2):135-139.
This study investigated the presence of cytokines interferon (IFN)-gamma, interleukins (IL) -6 and -8 in serum of cattle and buffaloes infected with Fasciola gigantica from one to 16 weeks post-infection...
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Postnatal exposure to a progestin does not prevent uterine adenogenesis in domestic dogs

Ponchon T, Lopez Merlo M, Faya M, Priotto M, Barbeito C, Gobello C

To assess the effects of a single supraphysiological postnatal administration of a progestogen on uterine glands in dogs, 10 females were randomly assigned to a medroxyprogesterone acetate 35 mg (MPA;...
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Lung adenoma development and NK activity in mice treated with multiple carcinogens

Lee YS, Seo JS, Chung HT, Cho KJ, Jang JJ

A wide-spectrum initiation model was investigated in mice. Sequential treatments with diethylnitrosamine, urethane and N-methylnitrosourea, with or without a promoter, phenobarbital, resulted in tumor formation in the lungs in...
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Effect of a Selective 5-HT4 Receptor Partial Agonist Tegaserod on Sensory Function and Compliance of Small Intestine in Humans

Jeong JJ, Choi MG, Cho YK, Jun EJ, Cho YS, Chung WC, Lee IS, Kim SW, Choi SW, Chung IS

  • KMID: 2255868
  • Korean J Neurogastroenterol Motil.
  • 2004 Jun;10(1):35-42.
BACKGROUND/AIMS: Disturbances in visceral perception contribute to postprandial symptoms in patients with functional dyspepsia. However, the mechanism of perceiving sensation has not been clearly defined. Our aim in this study...
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Mechanical Thrombectomy in Strokes with Large-Vessel Occlusion Beyond 6 Hours: A Pooled Analysis of Randomized Trials

Vidale S, Longoni M, Valvassori L, Agostoni E

BACKGROUND AND PURPOSE: Mechanical thrombectomy with or without intravenous thrombolysis is indicated in the acute treatment of ischemic strokes caused by an emergent large-vessel occlusion (ELVO) within 6 hours from...
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