- RNAi: A Recent Revolutionary Tool for Understanding of Basic Biology
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Jung DK, Cho YS, Lee WK
- KMID: 2224730
- Korean J Clin Microbiol.
- 2007 Apr;10(1):1-5.
RNA interference (RNAi) is a gene-silencing technology by which small double-stranded RNAs are used to target the degradation of RNA with complementary sequence. RNAi is found in a wide variety... -
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- Dependence of RIG-I Nucleic Acid-Binding and ATP Hydrolysis on Activation of Type I Interferon Response
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Baek YM, Yoon S, Hwang YE, Kim DE
- KMID: 2349886
- Immune Netw.
- 2016 Aug;16(4):249-255.
- doi: 10.4110/in.2016.16.4.249
Exogenous nucleic acids induce an innate immune response in mammalian host cells through activation of the retinoic acid-inducible gene I (RIG-I). We evaluated RIG-I protein for RNA binding and ATPase... -
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- Sequence analysis of segment A gene of a very virulent infectious bursal disease virus recently isolated in Korea
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Oh HS, Lee JH, Kwon HM, Sung HW
- KMID: 1991813
- Korean J Vet Res.
- 2011 Mar;51(1):37-46.
Infectious bursal disease virus (IBDV) is a member of the Avibirnavirus genus of the Birnaviridae family which genome consists of two segments (A and B) of double stranded RNA. Segment... -
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- Small Double-Stranded RNA Mediates the Anti-Cancer Effects of p21(WAF1/ClP1) Transcriptional Activation in a Human Glioma Cell Line
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Dong Z, Dang Y, Chen Y
- KMID: 2386458
- Yonsei Med J.
- 2014 Mar;55(2):324-330.
PURPOSE: This study was conducted to investigate the small double-stranded RNA (dsRNA) mediated anti-tumor effects of p21(WAF1/ClP1) (p21) transcriptional activation in vitro in the human glioma SHG-44 cell line. MATERIALS AND... -
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- Mobile transposon-like element, clone MTi7: Finding its role(s) by RNA interference
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Park CE, Shin MR, Jeon EH, Cho SW, Lee SH, Kim K, Kim NH, Lee KA
- KMID: 2304563
- Korean J Fertil Steril.
- 2003 Dec;30(4):299-307.
OBJECTIVES: The present study was conducted to evaluate the mobile transposon-like element, clone MTi7 (MTi7) expression in the mouse ovary and to determine its role(s) in the mouse oocytes by... -
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- Effect of RNA Interference-Mediated Suppression of p75 on the Viability of Rat Notochordal Cells
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Park JB, Chang DG, Oh SY, Park EY
- KMID: 2362174
- Asian Spine J.
- 2016 Dec;10(6):985-992.
- doi: 10.4184/asj.2016.10.6.985
STUDY DESIGN: In vitro cell culture model. PURPOSE: To investigate the effects of RNA interference (RNAi) on p75 expression and viability of rat notochordal cells treated with serum deprivation. OVERVIEW OF LITERATURE:... -
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- The optimal concentration of siRNA for gene silencing in primary cultured astrocytes and microglial cells of rats
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Ki KH, Park DY, Lee SH, Kim NY, Choi BM, Noh GJ
- KMID: 1766501
- Korean J Anesthesiol.
- 2010 Dec;59(6):403-410.
- doi: 10.4097/kjae.2010.59.6.403
BACKGROUND: Small interfering RNAs (siRNAs) have been used to knockdown specific gene expression in various cells. Astrocytes and microglial cells play a key role in fundamental central nervous system functions... -
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- Double-stranded RNA virus in Korean Isolate IH-2 of Trichomonas vaginalis
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Kim JW, Chung PR, Hwang MK, Choi EY
- KMID: 1720531
- Korean J Parasitol.
- 2007 Jun;45(2):87-94.
- doi: 10.3347/kjp.2007.45.2.87
In this study, we describe Korean isolates of Trichomonas vaginalis infected with double-stranded (ds) RNA virus (TVV). One T. vaginalis isolate infected with TVV IH-2 evidenced weak pathogenicity in the... -
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- Differential Protein Expressions in Virus-Infected and Uninfected Trichomonas vaginalis
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He D, Pengtao G, Ju Y, Jianhua L, He L, Guocai Z, Xichen Z
- KMID: 2379413
- Korean J Parasitol.
- 2017 Apr;55(2):121-128.
- doi: 10.3347/kjp.2017.55.2.121
Protozoan viruses may influence the function and pathogenicity of the protozoa. Trichomonas vaginalis is a parasitic protozoan that could contain a double stranded RNA (dsRNA) virus, T. vaginalis virus (TVV).... -
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- Ribosomal Protein L19 and L22 Modulate TLR3 Signaling
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Yang EJ, Seo JW, Choi IH
- KMID: 2150702
- Immune Netw.
- 2011 Jun;11(3):155-162.
- doi: 10.4110/in.2011.11.3.155
BACKGROUND: Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) and induces inflammation. In this study we attempted to ascertain if there are endogenous host molecules controlling the production of cytokines... -
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- Past, Present, and Future of Allergy in Korea
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Kim YY
- KMID: 2133802
- Allergy Asthma Immunol Res.
- 2010 Jul;2(3):155-164.
- doi: 10.4168/aair.2010.2.3.155
Korean allergology has made great progress in keeping pace with global scientific advances in spite of a short history. Outstanding academic and scientific researches have been performed in a variety... -
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- Isolation and Characterization of Reovirus in Korea
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Song KJ, Kang BC, Lee YE, Baek LJ, Lee YJ, Song JW
- KMID: 2096741
- J Korean Soc Virol.
- 1999 Jun;29(2):65-74.
Reovirus was found to inhabit both the respiratory and the enteric tract of human find animals. The genome of reovirus comprises 10 segments of double-stranded RNA, total size 24 kbp.... -
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- Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes
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Kim Y, Kim EY, Seo YM, Yoon TK, Lee WS, Lee KA
- KMID: 1743692
- Clin Exp Reprod Med.
- 2012 Jun;39(2):58-67.
- doi: 10.5653/cerm.2012.39.2.58
OBJECTIVE: Previously, we identified that transketolase (Tkt), an important enzyme in the pentose phosphate pathway, is highly expressed at 2 hours of spontaneous maturation in oocytes. Therefore, this study was... -
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- Viral Effects of a dsRNA Mycovirus (PoV-ASI2792) on the Vegetative Growth of the Edible Mushroom Pleurotus ostreatus
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Song HY, Choi HJ, Jeong H, Choi D, Kim DH, Kim JM
- KMID: 2366453
- Mycobiology.
- 2016 Dec;44(4):283-290.
- doi: 10.5941/MYCO.2016.44.4.283
A double-stranded RNA (dsRNA) mycovirus was detected in malformed fruiting bodies of Pleurotus ostreatus strain ASI2792, one of bottle cultivated commercial strains of the edible oyster mushroom. The partial RNA-dependent... -
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- Effect of Polyinosinic-Polycytidylic Acid on MUC5B Expression in Human Airway Epithelial Cells
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Choi YH, Bae CH, Kim HG, Seo BH, Choi YS, Song SY, Kim YD
- KMID: 2063270
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2015 Sep;58(9):615-621.
- doi: 10.3342/kjorl-hns.2015.58.9.615
BACKGROUND AND OBJECTIVES: Polyinosinic-polycytidylic acid (Poly I:C) is structurally similar to double-stranded RNA, and is known to induce various inflammatory mediators and to cause inflammatory reactions in airway epithelial cells.... -
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- Role of Toll-like Receptor 3 Variants in Aspirin-Exacerbated Respiratory Disease
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Palikhe NS, Kim SH, Kim JH, Losol P, Ye YM, Park HS
- KMID: 2130364
- Allergy Asthma Immunol Res.
- 2011 Apr;3(2):123-127.
- doi: 10.4168/aair.2011.3.2.123
PURPOSE: Although the mechanism of virus-induced, aspirin-exacerbated respiratory disease (AERD) is not known fully, direct activation of viral components through Toll-like receptor 3 (TLR3) has been suggested. TLR3 recognizes double-stranded... -
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- Association of TLR3 gene polymorphism with IgG subclass deficiency and the severity in patients with aspirin-intolerant asthma
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Kim SH, Yang EM, Jung HM, Pham DL, Choi HN, Ban GY, Park HS
- KMID: 2346755
- Allergy Asthma Respir Dis.
- 2016 Jul;4(4):264-270.
- doi: 10.4168/aard.2016.4.4.264
PURPOSE: Toll-like receptor 3 (TLR3) recognizes to viral double-stranded RNA and is involved in antiviral defenses. A probable role of TLR3 gene variants in the pathogenesis of aspirin-intolerant asthma (AIA)... -
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- Double-stranded RNA Induces Inflammatory Gene Expression in Schwann Cells: Implication in the Wallerian Degeneration
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Lee H, Park C, Choi SY, Oh SB, Park K, Kim JS, Lee SJ
- KMID: 1611428
- Korean J Physiol Pharmacol.
- 2004 Oct;8(5):253-257.
Schwann cells play an important role in peripheral nerve regeneration. Upon neuronal injury, activated Schwann cells clean up the myelin debris by phagocytosis, and promote neuronal survival and axon outgrowth... -
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- Studying the Effect of Downregulating Autophagy-Related Gene LC3 on TLR3 Apoptotic Pathway Mediated by dsRNA in Hepatocellular Carcinoma Cells
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Wang G, Zhang M, Li Y, Zhou J, Chen L
- KMID: 2367521
- Cancer Res Treat.
- 2017 Jan;49(1):230-245.
- doi: 10.4143/crt.2015.506
PURPOSE: The purpose of this study is to examine the role of the double-stranded RNA (dsRNA) activated Toll–interleukin-1 receptor domain-containing adaptor inducing interferon β (TRIF) signal pathway in triggering apoptosis... -
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- Jennerian reassortment rotavirus vaccines
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Kim KH
- KMID: 2440541
- Korean J Pediatr Infect Dis.
- 1996 May;3(1):23-28.
- doi: 10.14776/kjpid.1996.3.1.23
RQtavirus(Rv) is the most common cause of severe dehydratine diarrhea in infants and young children worldwide, infecting nearly every child in the first few years of life, and thus justif}-ing... -
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