Korean J Clin Microbiol.
2007 Apr;10(1):1-5.
RNAi: A Recent Revolutionary Tool for Understanding of Basic Biology
- Affiliations
-
- 1Department of Laboratory Medicine, Hongseong Medical Center, Korea.
- 2Samkwang Medical Laboratory, Samkwang Medical Science Institute, Seoul, Korea.
- 3Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea. leewk@knu.ac.kr
Abstract
- RNA interference (RNAi) is a gene-silencing technology by which small double-stranded RNAs are used to target the degradation of RNA with complementary sequence. RNAi is found in a wide variety of organisms (Caenorhabditis elegans, insects, plants, microorganisms and animals). With RNAi, we have harnessed the gene function to be explored, revolutionized our ability to perform large-scale genetic screens, and even therapeutic potential.
