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The Effect of 5-Fluorouraci1 on the Activity of the Retinal Pigment Epithelium in Vitro

Ko MK

  • KMID: 2107487
  • J Korean Ophthalmol Soc.
  • 1987 Dec;28(6):1239-1245.
Fluorouracil Was effective in controlling the in vitro cellular proliferation. When given with cultured human retinal pigment epithelial cell, fluoroirracil decreased the cellular activity of the cultured retinal pigment epithelial...
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Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation

Oh YS, Heo K, Kim EK, Jang JH, Bae SS, Park JB, Kim YH, Song M, Kim SR, Ryu SH, Kim IH, Suh PG

NHERF1/EBP50 (Na⁺/H⁺ exchanger regulating factor 1; Ezrin-binding phosphoprotein of 50 kDa) organizes stable protein complexes beneath the apical membrane of polar epithelial cells. By contrast, in cancer cells without any fixed...
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The Changes of Marginal Epithelial Cells in Corneal Wound Healing

Lee TH, Han SJ, Lee JL, Lee HY

  • KMID: 2123470
  • J Korean Ophthalmol Soc.
  • 1996 Jul;37(7):1105-1110.
The changes of marginal epithelial cells in corneal wound healing were observed in a rabbit. The randomly assigned three eyes in the rabbits were extracted at first, third, and eighteenth...
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Development of Sinusoidal Wall in Human Fetal Liver: A Morphological Study on Endothelial Cells, Kupffer Cells and Transmural Migration of Erythropoietic Cells

Lee WG, Kim KY, Lee WB

The 5 cases of human fetal liver aged from 11 to 23 weeks of gestation were investigated for the ultrastructure of sinusoidal wall by electron microscopy. The endothelial cells deficient...
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Adherence of Acanthamoeba Lugdunensis on the Corneal Epithelium in Organ Cultured Human Cornea: A Scanning and Transmission Electron Microscopy Study

Kim SM, Hahn TW

  • KMID: 2147614
  • J Korean Ophthalmol Soc.
  • 1999 May;40(5):1195-1201.
The purpose of this study was to investigate the ability of Acanthamoeba to adhere to the epithelial cells of human cornea. Human corneas, obtained through the eye bank of Catholic...
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Mouse Fyn induces pseudopodium formation in Chinese hamster ovary cells

An L, Liu S, Zhang W, Zhang Y, Huang Y, Hu X, Chen S, Zhao S

Molecular mechanisms underlying the effects of Fyn on cell morphology, pseudopodium movement, and cell migration were investigated. The Fyn gene was subcloned into pEGFP-N1 to produce pEGFP-N1-Fyn. Chinese hamster ovary...
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Activation of small Rho GTPases by blebbistatin in PC12 cells

Kim EG, Shin EY

  • KMID: 1498922
  • J Biomed Res.
  • 2013 Jun;14(2):60-64.
Neuronal differentiation is a complex biological process accompanying cytoskeletal reorganization, including neurite outgrowth and growth cone formation. Therefore, neuronal differentiation is critically regulated by actin-related signaling proteins, such as small...
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Anti-Migration and Anti-Invasion Effects of Curcumin via Suppression of Fascin Expression in Glioblastoma Cells

Park KS, Yoon SY, Park SH, Hwang JH

BACKGROUND: The natural compound curcumin was known to inhibit migration and invasion of glioblastoma (GBM) cells. Fascin, a kind of actin-binding proteins, is correlated with migration and invasion of GBM...
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Regulation of retinal angiogenesis by endothelial nitric oxide synthase signaling pathway

Ha JM, Jin SY, Lee HS, Shin HK, Lee DH, Song SH, Kim CD, Bae SS

Angiogenesis plays an essential role in embryo development, tissue repair, inflammatory diseases, and tumor growth. In the present study, we showed that endothelial nitric oxide synthase (eNOS) regulates retinal angiogenesis....
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Histological and Biochemical Study on the Effect of Cadmium Chloride on the Rat Testis

Kim WS, Myung PK, Yang EJ, Cho KJ

  • KMID: 2092712
  • Korean J Anat.
  • 2000 Feb;33(1):29-40.
Although cadmium is a well known heavy metal which has an influence testis and brings about male infertility, the mechanism of action in the testis is still fully unknown. In...
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Gene expression of MC3T3-E1 osteoblastic cells on titanium and zirconia surface

Gong SH, Lee H, Pae A, Noh K, Shin YM, Lee JH, Woo YH

PURPOSE: This study was performed to define attachment and growth behavior of osteoblast-like cells and evaluate the gene expression on zirconia compared to titanium. MATERIALS AND METHODS: MC3T3-E1 cells were cultured...
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Cell attachment and proliferation of bone marrow-derived osteoblast on zirconia of various surface treatment

Pae A, Lee H, Noh K, Woo YH

PURPOSE: This study was performed to characterize the effects of zirconia coated with calcium phosphate and hydroxyapatite compared to smooth zirconia after bone marrow-derived osteoblast culture. MATERIALS AND METHODS: Bone marrow-derived...
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Astaxanthin induces migration in human skin keratinocytes via Rac1 activation and RhoA inhibition

Ritto D, Tanasawet , Singkhorn , Klaypradit W, Hutamekalin P, Tipmanee V, Sukketsiri W

BACKGROUND/OBJECTIVES: Re-epithelialization has an important role in skin wound healing. Astaxanthin (ASX), a carotenoid found in crustaceans including shrimp, crab, and salmon, has been widely used for skin protection. Therefore,...
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Cellular responses on anodized titanium discs coated with 1 alpha,25-dihydroxyvitamin D3 incorporated Poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles

Cho YJ, Heo SJ, Koak JY, Kim SK, Lee JH

  • KMID: 2321753
  • J Korean Acad Prosthodont.
  • 2008 Dec;46(6):620-627.
STATEMENT OF PROBLEM: A biochemical approach for surface modification has offered an alternative for physicochemical and morphological methods to obtain desirable bone-implant interfaces. PURPOSE: The purpose of the present study was...
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Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway

Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W

BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found...
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Cellular attachment and gene expression of osteoblast-like cells on zirconia ceramic surfaces

Pae A, Lee H, Kim HS, Baik J, Woo YH

  • KMID: 2118753
  • J Korean Acad Prosthodont.
  • 2008 Jun;46(3):227-237.
STATEMENT OF PROBLEM: Zirconium oxide can be a substitute to titanium as implant materials to solve the esthetic problems of dark color in the gingival portion of implant restorations....
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Osteoinduction using by Human BMP-2-physio- functional Bioactive Ceramics

Kim H, Moon SH, Lee JW, Kim HM, Park M, Lee HM

PURPOSE: To assess the properties and the osteogenic potency of the calcium phosphate-recombinant human morphogenetic protein-2 (CaP-rhBMP-2 composite) on glass-ceramics. MATERIALS AND METHODS: Bioactive glass-ceramics,as a scaffold, and a calcium phosphate...
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