- Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells
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Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC
- KMID: 927133
- Exp Mol Med.
- 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and... -
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- Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex
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Jeon WJ, Kim SH, Seo MS, Kim Y, Kang UG, Juhnn YS, Kim YS
- KMID: 1094123
- Exp Mol Med.
- 2008 Aug;40(4):435-444.
- doi: 10.3858/emm.2008.40.4.435
Repeated electroconvulsive seizure (ECS), a model for electroconvulsive therapy (ECT), exerts neuroprotective and proliferative effects in the brain. This trophic action of ECS requires inhibition of apoptotic activity, in addition... -
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- MALT (Mucosa-Associated Lymphoid Tissue) Lymphoma of the Colon
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Park JH, Lee JH
- KMID: 1792770
- Korean J Gastroenterol.
- 2010 Apr;55(4):213-216.
- doi: 10.4166/kjg.2010.55.4.213
No abstract available. -
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- Norcantharidin Induces Human Melanoma A375-S2 Cell Apoptosis through Mitochondrial and Caspase Pathways
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An WW, Wang MW, Tashiro SI, Onodera S, Ikejima T
- KMID: 2157686
- J Korean Med Sci.
- 2004 Aug;19(4):560-566.
- doi: 10.3346/jkms.2004.19.4.560
Norcantharidin (NCTD) is the demethylated form of cantharidin, which is the active substance of mylabris. To examine the pathway of NCTD-induced A375-S2 cell death, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-dipheyltetrazolium bromide (MTT) assay,... -
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- Bfl-1 Gene Expression in Breast Cancer: Its Relationship with other Prognostic Factors
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Yoon HS, Hong SH, Kang HJ, Ko BK, Ahn SH, Huh JR
- KMID: 2157626
- J Korean Med Sci.
- 2003 Apr;18(2):225-230.
- doi: 10.3346/jkms.2003.18.2.225
The Bfl-1 gene, which was isolated from human fetal liver and only recently described, is a member of the Bcl-2 gene family. Reverse transcriptase-polymerase chain reaction was performed on RNA... -
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- Induction of Bis, a Bcl-2-binding protein, in reactive astrocytes of the rat hippocampus following kainic acid-induced seizure
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Lee MY, Kim SY, Choi JS, Choi YS, Jeon MH, Lee JH, Kim IK, Lee JH
- KMID: 1081467
- Exp Mol Med.
- 2002 May;34(2):167-171.
The expression of Bis (also called Bag-3), a Bcl-2-binding protein, was investigated in the rat kainic acid (KA) model of temporal lobe epilepsy. Western blot analysis showed a significant increase... -
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- Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Esophagus, Manifesting as a Submucosal Tumor
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Jung JG, Kang HW, Hahn SJ, Choi JS, Kim EJ
- KMID: 1775749
- Korean J Gastroenterol.
- 2013 Aug;62(2):117-121.
- doi: 10.4166/kjg.2013.62.2.117
We report a case of primary mucosa-associated lymphoid tissue (MALT) lymphoma in the esophagus that manifested as a large submucosal tumor (SMT). Primary esophageal lymphoma is very rare, occurring in... -
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- Exposure to Cerium Oxide Nanoparticles Is Associated With Activation of Mitogen-activated Protein Kinases Signaling and Apoptosis in Rat Lungs
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Rice KM, Nalabotu S, Manne ND, Kolli MB, Nandyala G, Arvapalli , Ma JY, Blough ER
- KMID: 2381462
- J Prev Med Public Health.
- 2015 May;48(3):132-141.
- doi: 10.3961/jpmph.15.006
OBJECTIVES: With recent advances in nanoparticle manufacturing and applications, potential exposure to nanoparticles in various settings is becoming increasing likely. No investigation has yet been performed to assess whether respiratory... -
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- The Effects of Family History of Colorectal Cancer on the Development of Colorectal Adenoma
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Choi MY, Kim BG, Kim JW, Lee KL, Jeong JB, Lee JK, Jung YJ, Kim W, Ahn DW, Kim YH, Joo SK, Chang MS, Kwon HJ
- KMID: 1718464
- Korean J Gastroenterol.
- 2012 Jul;60(1):36-41.
- doi: 10.4166/kjg.2012.60.1.36
BACKGROUND/AIMS: Early detection of polyp is important for the prevention of colorectal cancer (CRC). There have been few studies to investigate the relationship between colorectal adenoma and family history of... -
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- Growth Inhibition of Hepatocellular Carcinoma Huh7 Cells by Lactobacillus casei Extract
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Han DJ, Kim JB, Park SY, Yang MG, Kim H
- KMID: 1793166
- Yonsei Med J.
- 2013 Sep;54(5):1186-1193.
- doi: 10.3349/ymj.2013.54.5.1186
PURPOSE: Lactobacillus casei (L. casei) is known to exert anti-proliferation effects on many types of cancer cells. However, the effect of L. casei on liver cancer has not been reported.... -
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- Correlations of bcl-2 expression with clinicopathological features in breast cancer
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Lee HD, Koo JY, Jung WH
- KMID: 699952
- Yonsei Med J.
- 1997 Aug;38(4):206-211.
- doi: 10.3349/ymj.1997.38.4.206
To evaluate the prognostic significance of bcl-2, we investigated the correlation of bcl-2 expression with the established indicators of prognosis and tumor behavior in breast cancer. This study included a... -
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- Cell proliferation index and the expression of p53 and Bcl-2 in tumorous and non-tumorous lesions of hepatocellular carcinoma and metastatic liver cancer
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Yoon DS, Cheong JH, Park YN, Kwon SW, Chi HS, Kim BR
- KMID: 711579
- Yonsei Med J.
- 1998 Oct;39(5):424-429.
- doi: 10.3349/ymj.1998.39.5.424
In the development of a cancer, unlimited cell proliferation has been believed to play an important role. In addition, a programmed cell death called apoptosis, which is regulated by several... -
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- Activated Protein C Protects Myocardium Via Activation of Anti-apoptotic Pathways of Survival in Ischemia-reperfused Rat Heart
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Ding JW, Tong XH, Yang J, Liu ZQ, Zhang Y, Yang J, Li S, Li L
- KMID: 1779231
- J Korean Med Sci.
- 2010 Nov;25(11):1609-1615.
- doi: 10.3346/jkms.2010.25.11.1609
Activated protein C (APC) is known to be beneficial on ischemia reperfusion injury in myocardium. However, the protection mechanism of APC is not fully understood. The purpose of this study... -
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- Prologation of c-Jun N-Terminal Kinase is Associated with Cell Death Induced by Tumor Necrosis Factor Alpha in Human Chondrocytes
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Yoon HS, Kim HA
- KMID: 2157687
- J Korean Med Sci.
- 2004 Aug;19(4):567-573.
- doi: 10.3346/jkms.2004.19.4.567
The aim of this study was to elucidate the role of JNK signaling pathway involved in tumor necrosis factor-alpha (TNF-alpha)-induced death of chondrocytes. Primary chondrocyte cultures were obtained from human... -
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- Cilostazol Protects Endothelial Cells Against Lipopolysaccharide-Induced Apoptosis Through ERK1/2- and P38 MAPK-Dependent Pathways
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Lim JH, Woo JS, Shin YW
- KMID: 1717961
- Korean J Intern Med.
- 2009 Jun;24(2):113-122.
- doi: 10.3904/kjim.2009.24.2.113
BACKGROUND/AIMS: We examined the effects of cilostazol on mitogen-activated protein kinase (MAPK) activity and its relationship with cilostazol-mediated protection against apoptosis in lipopolysaccharide (LPS)-treated endothelial cells. METHODS: Human umbilical vein... -
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- Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells
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Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH
- KMID: 1093633
- J Vet Sci.
- 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,... -
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- Telomerase and Apoptosis in the Placental Trophoblasts of Growth Discordant Twins
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Kim SY, Lee SP, Lee JS, Yoon SJ, Jun G, Hwang YJ
- KMID: 1381251
- Yonsei Med J.
- 2006 Oct;47(5):698-705.
- doi: 10.3349/ymj.2006.47.5.698
In an effort to investigate the molecular basis of growth discordance in embryos that experience the same uterine environment, we compared telomerase activity and apoptosis in placental trophoblasts obtained from... -
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- Protective Effect of Ultra Low Molecular Weight Heparin on Glutamate-Induced Apoptosis in Cortical Cells
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Yu TG, Zhang QZ, Zhang ZG, Wang WW, Ji SL, Du GH
- KMID: 724266
- Yonsei Med J.
- 2008 Jun;49(3):486-495.
- doi: 10.3349/ymj.2008.49.3.486
PURPOSE: To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS: Cell... -
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- Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells
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Gong X, Wang M, Wu Z, Tashiro SI, Onodera S, Ikejima T
- KMID: 1103322
- Exp Mol Med.
- 2004 Dec;36(6):551-556.
Pseudolaric acid B was isolated from Pseudolarix kaempferi Gordon (Pinaceae) and was evaluated for the anti-cancer effect in HeLa cells. We observed that pseudolaric acid B inhibited cell proliferation and... -
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- Malignant Solitary Fibrous Tumor of Retroperitoneum Mimicking Gastric Submucosal Tumor
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Bae JM, Kim SW, Kim SW, Song SK
- KMID: 991469
- Korean J Gastroenterol.
- 2011 Jan;57(1):47-50.
- doi: 10.4166/kjg.2011.57.1.47
Solitary fibrous tumors (SFTs) are an uncommon neoplasm characterized by the proliferation of spindle cells. The diagnostic criteria of malignant solitary fibrous tumors (MSFTs) include high cellularity, high mitotic activity... -
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