Korean J Gastroenterol.  2010 Apr;55(4):213-216. 10.4166/kjg.2010.55.4.213.

MALT (Mucosa-Associated Lymphoid Tissue) Lymphoma of the Colon

• Park JH
• Lee JH

• KMID: 1792770
• DOI: http://doi.org/10.4166/kjg.2010.55.4.213

Abstract

No abstract available.

MeSH Terms

Antigens, CD20/metabolism
Colonic Neoplasms/*diagnosis/pathology/surgery
Colonoscopy
Humans
Lymphoma, B-Cell, Marginal Zone/*diagnosis/pathology/surgery
Male
Middle Aged
Proto-Oncogene Proteins c-bcl-2/metabolism

Figure

• 

  Fig. 1. Colonoscopic findings. (A) A single sessile polypoid lesion was noted on the cecum. (B) The lesion was observed more clearly after spraying indigocarmine.

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  Fig. 2. Histological findings. (A) Biopsy specimen showed diffuse infiltration of atypical lymphocytes in the mucosal layer (H&E, ×100). (B) Immunohistochemical stain for CD 20 was diffusely positive (×100), (C) and also stain for bcl-2 was positive (×100), (D) but stain for CD3 was negative (×100).

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  Fig. 3. Miniprobe EUS showed an 1.2 cm sized hypoechoic mass with focally disrupted submucoal and intact proper muscle layer of colon.

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  Fig. 4. Pathologic findings. (A) Gross specimen demonstrated multiple nodular lesions (arrows) on the cecum and terminal ileum. (B) The resection specimen showed diffuse infiltration of atypical lymphocytes in the mucosal and submucosal layer.

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