J Korean Med Sci.  2005 Apr;20(2):325-328. 10.3346/jkms.2005.20.2.325.

A Case of Multiple Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Colon Identified as Simple Mucosal Discoloration

• Lee YG
• Lee S
• Han SW
• Lee JS

• KMID: 1095213
• DOI: http://doi.org/10.3346/jkms.2005.20.2.325

Abstract

Most colonic multiple mucosa-associated lymphoid tissue (MALT) lymphomas are confirmed with a histologic and immunohistochemical staining of the mucosal biopsy specimen obtained during colonoscopic examinations. Endoscopically, colonic MALT lymphomas frequently appear as protruding and/or ulcerative lesions, and there are not so many reports of colonic MALT lymphoma as compared to the frequent reports of MALT lymphoma of stomach. We report a unique case of colonic MALT lymphoma presenting as a simple reddish discoloration of mucosa; this presentation has never been describe before. Our patient was a 47-yr-old male who suffered from tenesmus and mucoid stool. A colonoscopy was accomplished, followed by a histologic examination and we diagnosed a colonic MALT lymphoma. Staging of the disease was done because this was necessary for choosing the modality of treatments. The patient was then treated with polychemotherapy in conjunction with radiation therapy.

Keyword

Colon; Lymphoma, Mucosa-Associated Lymphoid Tissue; Colonoscopy

MeSH Terms

Colonic Neoplasms/*pathology
Colonoscopy
Color
Humans
Intestinal Mucosa/*pathology
Lymphoma, Mucosa-Associated Lymphoid Tissue/*pathology
Male
Middle Aged

Figure

• 

  Fig. 1 Colonoscopic findings at admission. (A) Colonoscopy showing granular & reddish mucosal thickening in the rectum just above anus. (B) Colonoscopy showing reddish inflammatory mucosal swelling in the appendiceal orifice.

• 

  Fig. 2 Histologic findings of biopsy specimens. (A) Neoplastic lymphoid cells infiltrated colonic gland resembling a lymphoepithelial lesion (H&E, ×200). (B) Immunohistochemical stain for CD 20 showing diffuse reaction in the cell membrane. Lymphoepithelial lesions (arrow heads) are also positive for CD20 (×200).

• 

  Fig. 3 Colonoscopic findings after treatment. (A) Colonoscopy showing no definitive abnormal lesions in the rectum just above anus. (B) Colonoscopy showing normal appendiceal orifice.

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