- Pathogenesis and Management of Serrated Polyps: Current Status and Future Directions
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Anderson J
- KMID: 2070073
- Gut Liver.
- 2014 Nov;8(6):582-589.
- doi: 10.5009/gnl14248
Hyperplastic or serrated polyps were once believed to have little to no clinical significance. A subset of these polyps are now considered to be precursors to colorectal cancers (CRC) in... -
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- Molecules and their functions in autophagy
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Pyo JO, Nah J, Jung YK
- KMID: 1120125
- Exp Mol Med.
- 2012 Feb;44(2):73-80.
- doi: 10.3858/emm.2012.44.2.029
Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led to the identification of a number of genes involved... -
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- Cloning and sequencing of p33 in a Korean isolate of Theileria sergenti
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Kang SW, Choi EJ, Kweon CH
- KMID: 1715324
- Korean J Parasitol.
- 1997 Jun;35(2):105-110.
- doi: 10.3347/kjp.1997.35.2.105
The gene encoding the 33 kDa piroplasm surface protein of Theileria sergenti isolated in Korea was cloned and the nucleotide sequence was determined by dideoxy chain termination method. The cloned... -
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- Calcium cycling proteins in heartfailure, cardiomyopathy and arrhythmias
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Minamisawa S, Sato Y, Cho MC
- KMID: 1097100
- Exp Mol Med.
- 2004 Jun;36(3):193-203.
A growing body of evidence, including studies using genetically engineered mouse models, has shown that Ca2+ cycling and Ca2+ -dependent signaling pathways play a pivotal role in cardiac hypertrophy and... -
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- Knockdown of 14-3-3zeta enhances radiosensitivity and radio-induced apoptosis in CD133+ liver cancer stem cells
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Lee YK, Hur W, Lee SW, Hong SW, Kim SW, Choi JE, Yoon SK
- KMID: 2155342
- Exp Mol Med.
- 2014 Feb;46(2):e77.
- doi: 10.1038/emm.2013.151
14-3-3zeta is related to many cancer survival cellular processes. In a previous study, we showed that silencing 14-3-3zeta decreases the resistance of hepatocellular carcinoma (HCC) to chemotherapy. In this study,... -
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- Two Cases of Shwachman-Diamond Syndrome in Adolescents Confirmed by Genetic Analysis
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Cho WK, Jung IA, Kim J, Chae H, Kim M, Chung NG, Suh BK
- KMID: 2363194
- Ann Lab Med.
- 2015 Mar;35(2):269-271.
- doi: 10.3343/alm.2015.35.2.269
No abstract available. -
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- RET Fusion Genes in Korean Non-Small Cell Lung Cancer
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Yoo SS, Jin G, Jung HJ, Hong MJ, Choi JE, Jeon HS, Lee SY, Lim JO, Park JY
- KMID: 1777699
- J Korean Med Sci.
- 2013 Oct;28(10):1555-1558.
- doi: 10.3346/jkms.2013.28.10.1555
Recently, rearranged during transfection (RET) fusions have been identified in approximately 1% of non-small cell lung cancer (NSCLC). To know the prevalence of RET fusion genes in Korean NSCLCs, we... -
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- Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis
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Kim HS, Shen Q, Nam SW
- KMID: 2344168
- J Korean Med Sci.
- 2015 Oct;30(10):1375-1380.
- doi: 10.3346/jkms.2015.30.10.1375
A growing body of evidence suggests that epigenetic modifications are promising potential mechanisms in cancer research. Among the molecules that mediate epigenetic mechanisms, histone deacetylases (HDACs) are critical regulators of... -
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- RING Finger Proteins Are Involved in the Progression of Barrett Esophagus to Esophageal Adenocarcinoma: A Preliminary Study
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Wang XW, Wei W, Wang WQ, Zhao XY, Guo H, Fang DC
- KMID: 2070058
- Gut Liver.
- 2014 Sep;8(5):487-494.
- doi: 10.5009/gnl13133
BACKGROUND/AIMS: To investigate the differential expression of RING finger (RNF) proteins in Barrett esophagus (BE) and esophageal adenocarcinoma (EAC). METHODS: The differential expression of RNFs in normal esophagus (NE), BE, and... -
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- Phylogenetically interrelated ETS genes, ETV1, ERM and E1A-F locate on different chromosomes
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Jeon IS, Shapiro DN
- KMID: 1038161
- J Korean Med Sci.
- 1998 Aug;13(4):355-360.
- doi: 10.3346/jkms.1998.13.4.355
ETV1, ERM and E1A-F are members of the multigene ETS domain containing a class of transcription factors, first identified in the genome of the avian retrovirus E26. Based upon... -
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- Codon optimization of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells
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Gao J, Meng C, Chen Z, Li C, Liu G
- KMID: 1712311
- J Vet Sci.
- 2013 Dec;14(4):441-447.
- doi: 10.4142/jvs.2013.14.4.441
Rabbit hemorrhagic disease (RHD) is contagious and highly lethal. Commercial vaccines against RHD are produced from the livers of experimentally infected rabbits. Although several groups have reported that recombinant subunit... -
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- Identification of Antigenic Proteins in Trichomonas vaginalis
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Lee HY, Hyung S, Lee JW, Kim J, Shin MH, Ryu JS, Park SJ
- KMID: 1715638
- Korean J Parasitol.
- 2011 Mar;49(1):79-83.
- doi: 10.3347/kjp.2011.49.1.79
Trichomoniasis is a sexually transmitted disease due to infection with Trichomonas vaginalis, and it can cause serious consequences for women's health. To study the virulence factors of this pathogen, T.... -
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- Short-Cut Pathway to Synthesize Cellulose of Encysting Acanthamoeba
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Moon EK, Kong HH
- KMID: 1792132
- Korean J Parasitol.
- 2012 Dec;50(4):361-364.
The mature cyst of Acanthamoeba is highly resistant to various antibiotics and therapeutic agents. Cyst wall of Acanthamoeba are composed of cellulose, acid-resistant proteins, lipids, and unidentified materials. Because cellulose... -
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- Expressed sequence tags (ESTs) analysis of Acanthamoeba healyi
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Kong HH, Hwang MY, Kim HK, Chung DI
- KMID: 1039037
- Korean J Parasitol.
- 2001 Jun;39(2):151-160.
- doi: 10.3347/kjp.2001.39.2.151
Randomly selected 435 clones from Acanthamoeba healyi cDNA library were sequenced and a total of 387 expressed sequence tags (ESTs) had been generated. Based on the results of BLAST search,... -
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- Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled
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Jung H, Kim HJ, Lee SK, Kim R, Kopachik W, Han JK, Jho EH
- KMID: 1009391
- Exp Mol Med.
- 2009 Oct;41(10):695-706.
- doi: 10.3858/emm.2009.41.10.076
Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and... -
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- Properties of GST-CALM expressed in E. coli
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Kim JA, Kim SR, Jung YK, Woo SY, Seoh JY, Hong YS, Kim HL
- KMID: 1109309
- Exp Mol Med.
- 2000 Jun;32(2):93-99.
Clathrin-coated vesicles (CCVs) are involved in protein and lipid trafficking between intracellular compartments in eukaryotic cells. CCVs are composed of clathrin and assembly proteins. The clathrin assembly protein lymphoid... -
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- Brain site-specific proteome changes in aging-related dementia
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Manavalan , Mishra M, Feng L, Sze SK, Akatsu H, Heese K
- KMID: 2154258
- Exp Mol Med.
- 2013 Sep;45(9):e39.
This study is aimed at gaining insights into the brain site-specific proteomic senescence signature while comparing physiologically aged brains with aging-related dementia brains (for example, Alzheimer's disease (AD)). Our study... -
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- Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins
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Shah BH
- KMID: 1029937
- Exp Mol Med.
- 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells... -
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- Novel Pathogenic Variant (c.3178G>A) in the SMC1A Gene in a Family With Cornelia de Lange Syndrome Identified by Exome Sequencing
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Jang MA, Lee CW, Kim JK, Ki CS
- KMID: 2363269
- Ann Lab Med.
- 2015 Nov;35(6):639-642.
- doi: 10.3343/alm.2015.35.6.639
Cornelia de Lange syndrome (CdLS) is a clinically and genetically heterogeneous congenital anomaly. Mutations in the NIPBL gene account for a half of the affected individuals. We describe a family... -
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- Immunogenicity of baculovirus expressed recombinant proteins of Japanese encephalitis virus in mice
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Yang DK, Kweon CH, Kim BH, Lim SI, Kwon JH, Kim SH, Song JY, Han HR
- KMID: 1114853
- J Vet Sci.
- 2005 Jun;6(2):125-133.
Genes encoding for the premembrane and envelope (prME), envelope (E) and nonstructural protein (NS1) of Japanese encephalitis virus (JEV) were cloned. Each protein was expressed in baculovirus expression system. Of... -
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