- Antiproliferative effect of basic fibroblast growth factor-saporin mitotoxin on keratocytes in culture
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Wee WR, Parandoosh Z, Sakamoto T, Caton M, Nova M, McDonnell
- KMID: 1735150
- Korean J Ophthalmol.
- 1996 Jun;10(1):1-7.
- doi: 10.3341/kjo.1996.10.1.1
We evaluated the effect of the conjugate of basic fibroblast growth factor (FGF2) and saporin (FGF2-SAP) on proliferation of cultured keratocytes. Cultured rabbit and human keratocytes were incubated in medium... -
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- Wnt5a stimulates chemotactic migration and chemokine production in human neutrophils
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Jung YS, Lee HY, Kim SD, Park JS, Kim JK, Suh PG, Bae YS
- KMID: 2154246
- Exp Mol Med.
- 2013 Jun;45(6):e27.
Wnt5a is a ligand that activates the noncanonical Wnt signaling pathways (beta-catenin-independent pathways). Human neutrophils expressed several Wnt5a receptors, such as Frizzled 2, 5 and 8. Stimulation of human neutrophils... -
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- Effect of Basic Fibroblast Growth Factor-Saporin (bFGF-SAP) Conjugate on Bovine Choriocapillary Endothelial Cells
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Kim YH, Kim HS, Yoo JS
- KMID: 754377
- Korean J Ophthalmol.
- 2004 Dec;18(2):121-131.
- doi: 10.3341/kjo.2004.18.2.121
We evaluated the effect of a basic fibroblast growth factor (bFGF) and saporin conjugate (bFGF-SAP) on proliferation, migration and tubule formation in bovine choriocapillary endothelial cells (BCECs). Cell proliferation and... -
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- Interaction of TGF-beta1 and rhBMP-2 on Human Bone Marrow Stromal Cells Cultured in Collagen Gel Matrix
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Kim MK, Niyibizi C
- KMID: 720631
- Yonsei Med J.
- 2001 Jun;42(3):338-344.
- doi: 10.3349/ymj.2001.42.3.338
Transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-2 (BMP-2) are abundant proteins in the bone matrix. However, their interaction in controlling osteoblast differentiation is not clearly understood. In this study,... -
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- Effect of porcine bone morphogenetic protein on healing of bone defect in the rabbit radius
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Kim NH, Yang KH, Lee HM, Oh SH
- KMID: 1117765
- Yonsei Med J.
- 1992 Mar;33(1):54-63.
- doi: 10.3349/ymj.1992.33.1.54
Segmental long bone defects due to infection or trauma is a difficult problem to manage in patients. We studied the effect of porcine bone morphogenetic protein (pBMP) on healing of... -
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- Effects of Polycaprolactone-Tricalcium Phosphate, Recombinant Human Bone Morphogenetic Protein-2 and Dog Mesenchymal Stem Cells on Bone Formation: Pilot Study in Dogs
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Kim SJ, Kim MR, Oh JS, Han I, Shin SW
- KMID: 1777098
- Yonsei Med J.
- 2009 Dec;50(6):825-831.
- doi: 10.3349/ymj.2009.50.6.825
PURPOSE: The aim of this study was to evaluate the survival, proliferation, and bone formation of dog mesenchymal stem cells (dMSCs) in the graft material by using Polycaprolactone-tricalcium phosphate (PCL-TCP),... -
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- The Effects of Recombinant Human BMP-7, Prepared from a COS-7 Expression System, on the Proliferation and Differentiation of Rat Newborn Calvarial Osteoblasts
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Lee DH, Suh H, Han DW, Park BJ, Lee JW, Park JC
- KMID: 720897
- Yonsei Med J.
- 2003 Aug;44(4):593-601.
- doi: 10.3349/ymj.2003.44.4.593
A family of proteins, the bone morphogenetic proteins (BMPs), which promote osteoblast differentiation and bone mineralization, have recently been identified. One, BMP-7, has shown the ability to induce cartilage and... -
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- The potential molecular effects of bursal septpeptide II on immune induction and antitumor activity
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Zhou GF, Liu QT, Zhou B, Qiu YF, Liu XD, Ma ZY, Feng XL, Cao RB, Chen PY
- KMID: 2344305
- J Vet Sci.
- 2015 Sep;16(3):325-331.
- doi: 10.4142/jvs.2015.16.3.325
The bursa of Fabricius (BF) is the acknowledged central humoral immune organ in birds. Bursal septpeptide II (BSP-II) is an immunomodulatory bioactive peptide isolated from BF. To understand the effects... -
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- Effects of Protein Source and Energy Substrates on the In Vitro Development of Bovine Embryos in a Two-step Culture System
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Lim KT, Lee BC, Kang SK, Hwang WS
- KMID: 1099824
- J Vet Sci.
- 2003 Apr;4(1):73-78.
In this study, we examined the effects of a two-step culture system, which involves the use of different culture media for early cleavage and later stage embryos, on the in... -
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- Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells
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Soliman MM, El-Senosi , Salem MM, Hamid OM, Kazuhiro K
- KMID: 1726918
- J Vet Sci.
- 2009 Sep;10(3):197-201.
- doi: 10.4142/jvs.2009.10.3.197
Treatment of AIDS (HIV) and hepatitis C virus needs protease inhibitors (PI) to prevent viral replication. Uses of PI in therapy are usually associated with a decrease in body weight... -
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- Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells
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Park H, Park OJ, Shin J, Choi Y
- KMID: 1116197
- Exp Mol Med.
- 2005 Dec;37(6):524-532.
Receptor activator of NFkappaB ligand (RANKL) is known as a key regulator of osteoclastogenesis. However, the fact that fibroblasts and periodontal ligament cells express RANKL in response to bacterial substances,... -
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- Effect of Recombinant Human Epidermal Growth Factor Against Cutaneous Scar Formation in Murine Full-thickness Wound Healing
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Kim YS, Lew DH, Tark KC, Rah DK, Hong JP
- KMID: 1792930
- J Korean Med Sci.
- 2010 Apr;25(4):589-596.
- doi: 10.3346/jkms.2010.25.4.589
A visible cutaneous scar develops from the excess formation of immature collagen in response to an inflammatory reaction. This study examined the role of epidermal growth factor (EGF) in the... -
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- Improvement in Ovarian Tissue Quality with Supplementation of Antifreeze Protein during Warming of Vitrified Mouse Ovarian Tissue
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Kong HS, Kim EJ, Youm HW, Kim SK, Lee JR, Suh CS, Kim SH
- KMID: 2418799
- Yonsei Med J.
- 2018 Mar;59(2):331-336.
- doi: 10.3349/ymj.2018.59.2.331
Ice easily recrystallizes during warming after vitrification, and antifreeze protein (AFP) can inhibit the re-crystallization. However, no study has evaluated the effect of AFP treatment only thereon during warming. This... -
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- Effect of Antifreeze Protein on Mouse Ovarian Tissue Cryopreservation and Transplantation
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Lee JR, Youm HW, Lee HJ, Jee BC, Suh CS, Kim SH
- KMID: 2450353
- Yonsei Med J.
- 2015 May;56(3):778-784.
- doi: 10.3349/ymj.2015.56.3.778
PURPOSE: To investigate the effect of antifreeze protein (AFP) supplementation on ovarian vitrification and transplantation. MATERIALS AND METHODS: In this experimental study, we researched a total of 182 ovaries from 4-week-old... -
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- Inhibitory effects of osteoprotegerin on osteoclast formation and function under serum-free conditions
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Fu YX, Gu JH, Zhang YR, Tong XS, Zhao HY, Yuan Y, Liu XZ, Bian JC, Liu ZP
- KMID: 1712306
- J Vet Sci.
- 2013 Dec;14(4):405-412.
- doi: 10.4142/jvs.2013.14.4.405
The purpose of this study was to determine whether osteoprotegerin (OPG) could affect osteoclat differentiation and activation under serum-free conditions. Both duck embryo bone marrow cells and RAW264.7 cells were... -
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- Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages
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Shim HK, Kim JY, Kim MJ, Sim HS, Park DW, Sohn JW, Kim MJ
- KMID: 1009390
- Exp Mol Med.
- 2009 Oct;41(10):687-694.
- doi: 10.3858/emm.2009.41.10.075
Legionella bacterium, an intracellular pathogen of mononuclear phagocytes, causes acute fatal pneumonia, especially in patients with impaired cellular immune responses. Until recently, however, the toll-like receptor (TLR) engagement of bacterial... -
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- Effect of Fasciola gigantica excretory secretory antigen on rat hematological indices
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Ganga G, Varshney J, Sharma RL
- KMID: 1059196
- J Vet Sci.
- 2006 Jun;7(2):123-125.
- doi: 10.4142/jvs.2006.7.2.123
The present study was undertaken to investigate the effect of Fasciola gigantica excretory secretory antigen (Fg-ESA) on rat hematological indices. Fg-ESA was prepared by keeping thoroughly washed 40 F. gigantica flukes in 100 ml... -
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- Individual Variation in Growth Factor Concentrations in Platelet-rich Plasma and Its Influence on Human Mesenchymal Stem Cells
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Cho HS, Song IH, Park SY, Sung MC, Ahn MW, Song KE
- KMID: 1735857
- Korean J Lab Med.
- 2011 Jul;31(3):212-218.
- doi: 10.3343/kjlm.2011.31.3.212
BACKGROUND: The objective of this study was to explore whether individual variations in the concentration of growth factors (GFs) influence the biologic effects of platelet-rich plasma (PRP) on human mesenchymal... -
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- Netrin Inhibits Regenerative Axon Growth of Adult Dorsal Root Ganglion Neurons in Vitro
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Park JI, Seo IA, Lee HK, Park HT, Shin SW, Park YM, Ahn KJ
- KMID: 1127079
- J Korean Med Sci.
- 2007 Aug;22(4):641-645.
- doi: 10.3346/jkms.2007.22.4.641
Netrin is a neuronal guidance molecule implicated in the development of spinal commissural neurons and cortical neurons. The attractive function of netrin requires the receptor, Deleted in Colorectal Cancer (DCC),... -
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- Transdifferentiation of Cultured Bovine Lens Epithelial Cells into Myofibroblast-like Cells by Serum Modulation
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Kim JT, Lee EH, Chung KH, Kang IC, Lee DH, Joo CK
- KMID: 1734118
- Yonsei Med J.
- 2004 Jun;45(3):380-391.
- doi: 10.3349/ymj.2004.45.3.380
An after-cataract is caused by the proliferation of residual cells over the equator of the lens. These cells subsequently migrate to the posterior lens capsule, where they undergo aberrant differentiation... -
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