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Cerebral Palsy due to Intracranial Hemorrhage Caused by Consumptive Coagulopathy in Protein C Deficiency: A Case Report

Cho Y, Lee YM, Park ES, Choi JY, Park C, Rha DW

Protein C (PROC) is a potent anticoagulant inactivating coagulation factors Va and VIIIa. PROC deficiency is very rare condition inherited as an autosomal dominant or recessive trait, and associated with...
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Diagnosis of Severe Protein C Deficiency Confirmed by Presence of Rare PROC Gene Mutation

Lim MS, Shin JE, Lee SM, Eun HS, Park MS, Park KI, Namgung R, Lee KA, Lee JS

Protein C (PROC) deficiency is caused by mutations in the PROC gene on chromosome 2q14.3. Patients with PROC deficiency typically present distinguished purpura, intracerebral and intravascular coagulopathy, and ophthalmologic complications....
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Acute Stroke Associated With Combined Protein C and S Deficiency During Pregnancy

Kim MJ, Jung S, Kim BH, Lee CY, Oh HJ, Eum SW, Lee EJ, Kwon SB, Cho SJ, Hwang SH

  • KMID: 2343526
  • J Korean Neurol Assoc.
  • 2014 Aug;32(3):171-174.
Pregnancy related stroke is rare and poorly understood. A 28-year-old pregnant woman at 20 weeks of gestation presented with sudden headache and left homonymous hemianopsia. MRI revealed acute right posterior...
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Stroke Associated With Protein C and S deficiency in Neonate: Report of two Cases

Kim E, Cha EY, Kim SY, Lee W, Sung IK, Chun CS

  • KMID: 2144524
  • J Korean Soc Neonatol.
  • 2007 May;14(1):71-77.
Recently, cases of stroke with inherited disorders of blood coagulation have been reported in children. Deficiency of protein C or S predisposing to a hypercoagulable state has been associated with...
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SMV Thrombosis on Taking Oral Contraceptive with Protein C and Protein S Deficiency

Yeo MS, Kwon YS, Choi SH, Kim KH, Byun CG, Koh YT, Suh DY, Lee HJ

  • KMID: 2096373
  • J Korean Surg Soc.
  • 2006 Sep;71(3):222-225.
Mesenteric venous thrombosis (MVT) is uncommon, but it is often aggravated to a lethal form of intestinal ischemia. Multiple risk factors are associated with mesenteric venous thrombosis, including hypercoagulable or...
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A Case of Venous Thrombosis developed in a woman taking Oral Contraceptives with Antithrombin III, Protein C and Protein S deficiencies

Bae SJ, Kim JS, Kim JH, Yun YJ, Lee SA

  • KMID: 2077632
  • Korean J Obstet Gynecol.
  • 2006 Jun;49(6):1383-1388.
Oal contraceptives are one of the most frequently used methods of hormonal contraception. In general, oral contraceptives have proven to be safe for most women. However, the risk of deep...
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A Case of Renal Infarction associated with Protein C and S Deficiency

Yeo CD, Hwang HJ, Park SM, Son SW, Shin SJ, Song HC, Choi EJ, Chang YS

  • KMID: 2079635
  • Korean J Nephrol.
  • 2006 May;25(3):457-460.
Renal infarction usually occurs in patients with atrial fibrillation, valvular heart disease, trauma, renal artery stenosis, atherosclerosis, vasculitis, and hypercoagulable state. Protein C or S deficiency is an uncommon condition...
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Protein C and Protein S as a Risk Factor for Retinal Vein Occlusion

Lee KS, Chung JK, Lee SJ

  • KMID: 2337216
  • J Korean Ophthalmol Soc.
  • 2005 Nov;46(11):1796-1801.
PURPOSE: The authors evaluated the possibility of protein C and protein S as risk factors for retinal vein occlusion (RVO). METHODS: We evaluated the medical histories and performed laboratory tests,...
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Neonatal Purpura Fulminans Due to Homozygous Protein C Deficiency

Kim YG, Na BM, Lee GC, Kim MJ, Park HJ, Kim CY, Yoon TY

No abstract available.
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Protein C as a Differential Marker for Bacterial Infection among Pediatric Patients with Fever

Mo EH, Nam IH, Park KD

  • KMID: 1875806
  • Korean J Pediatr.
  • 2004 Aug;47(8):839-843.
PURPOSE: This study was performed to find the clinical significance in protein C as a differential marker in the beginning stage of infection and prognosis factor in severe infection among...
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Effect of Dexamethasone on Gene Expression of Surfactant Protein B and Surfactant Protein C

Park IS, Sohn JW, Yoon HJ, Shin DH, Park SS

  • KMID: 2318416
  • Tuberc Respir Dis.
  • 2003 Apr;54(4):439-448.
BACKGROUND: Surfactant protein B(SP-B) and surfactant protein C(SP-C) are important in accelerating surface spreading of surfactant phospholipid. The glucocorticoids accelerate the morphologic differentiation of epithelial cells into type II cells...
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A Case of Pulmonary Thromboem-bolism associated with Protein C Deficiency

Cho JH, Park CW, Cho BR, Choi DH, Cho SJ, Lee SH, Hwang SO, Ahn HC, Ahn M, Seo JY, You KC

  • KMID: 2100698
  • J Korean Soc Emerg Med.
  • 2003 Mar;14(1):125-128.
A pulmonary thromboembolism usually results from a serious complication of deep venous thrombosis (DVT). However, several prothrombotic genetic risk factors are known to predispose a patient to thrombotic events, with...
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Acute Arterial Occlusion Associated with Protein C and S Deficiencies

Jung EY, Cho YP, Jang HJ, Kim JS, Kim YH, Han MS

  • KMID: 2004584
  • J Korean Surg Soc.
  • 2003 Mar;64(3):269-274.
Sudden acute arterial occlusion can result from a multitude of pathological processes. Although the appearance and the secondary effects of an acute arterial occlusion are similar regardless of the underlying...
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Deep Venous Thrombosis of the Lower Extremity Associated with Protein C and/or S Deficiencies

Kim HK, Cho YP, Lee DH, Ahn JH, Jang HJ, Kim JS, Kim YH, Han MS

  • KMID: 1941136
  • J Korean Soc Vasc Surg.
  • 2002 Nov;18(2):237-242.
PURPOSE: Protein C and S deficiencies are frequently described as causes of the hypercoagulable states. The aim of this study was to evaluate the clinical features and prognosis of deep...
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A case of combined deficiency of antithrombin III and protein C complicated by recurrent venous thrombosis

Eum MS, Park YH, Seol JI, Chae SY, You MB, Kang KH, Lee BS, Ha CE, Park JS, Jung YH, Ahn SH, Lee HJ

  • KMID: 1866921
  • Korean J Med.
  • 2002 May;62(5):570-574.
Primary venous thrombosis caused by deficiency or qualitative abnormality of antithrombin III, protein C and protein S is usually inherited as an autosomal dominant trait. Usually, deep vein thrombosis or...
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Vascular Diseases Associated with Protein C and/or S Deficiencies

Cho YP, Lee DH, Jung SM, Jang HJ, Kim JS, Han MS

  • KMID: 1940663
  • J Korean Surg Soc.
  • 2002 Feb;62(2):181-186.
PURPOSE: There are a number of conditions that can lead to a hypercoagulable state, however, protein C and S deficiencies are frequently described as causes of the hypercoagulable states. The...
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A Case of Neonatal Purpura Fulminans Due to a Homozygous Protein C Deficiency

Jo JH, Oh CK, Kim MB, Jang HS, Kwon KS

  • KMID: 2146438
  • Korean J Dermatol.
  • 2002 Jan;40(1):38-43.
Homozygous protein C deficiency is a rare hereditary coagulation disorder that occurs most often in childhood and is characterized by widespread thrombosis of capillaries and venules, abrupt onset of ecchymoses...
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Comparative Quantitative Study of Surfactant Protein C mRNA by Filter Hybridization and Solution Hybridization in Rats

Kim JH, Sohn JW, Yang SC, Yoon HJ, Shin DH, Park SS

BACKGROUND: Surfactant protein C(SP-C) is a hydrophobic 5,000 dalton molecule. SP-C has the primary roles in accelerating surface spreading of a surfactant phospholipid. The filter hypbridization and solution hybridization assays...
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Anesthesia for Living Related Liver Transplantation in Homozygous Protein C Deficiency

Cheong MA, Hwang KS, Choi KT, Choi Y, Lee EJ, Chung EJ

Protein C exerts anticoagulant effects by inactivating factor Va and VIIIa and stimulating fibrinolysis. The homozygous protein C deficiency is extremely rare and often results in life threatening thrombosis and...
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A Case of Antiphospholipid Syndrome Associated with Protein C Deficiency

Nam YS, Han SY, Choi DH, Yoon TK, Cha KY

  • KMID: 2085126
  • Korean J Fertil Steril.
  • 1999 Apr;26(1):123-126.
A successful outcome of pregnancy requires an efficient uteroplacental vascular system. Since this system may be compromised by disorders of haemostasis associated with a prothrombotic state, maternal thrombophilia might be...
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