- Responsive site on the thrombospondin-1 promotor to down-regulation by phorbol 12-myristate 13-acetate in porcine aortic endothelial cells
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Kim SA, Hong KJ
- KMID: 755077
- Exp Mol Med.
- 2000 Sep;32(3):135-140.
Thrombospondin-1 (TSP-1), a multifunctional extracellular matrix protein, inhibits neovascularization and is implicated in the regression of tumor growth and metastasis. We found that the synthesis of TSP-1 in... -
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- Analysis of the precore and core promoter DNA sequence in liver tissues from tients with hepatocellular carcinoma
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Cho SW, Shin YJ, Hahm KB, Jin JH, Kim YS, Kim JH, Kim HJ
- KMID: 1731317
- J Korean Med Sci.
- 1999 Aug;14(4):424-430.
- doi: 10.3346/jkms.1999.14.4.424
To investigate the role of mutant hepatitis B virus (HBV) in the development of hepatocellular carcinoma (HCC), 20 patients with HCC were studied for precore and core promoter mutations in... -
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- Characterization of regulatory elements on the promoter region of human ATP-citrate lyase
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Moon YA, Kim KS, Cho UH, Yoon DJ, Park SW
- KMID: 1029940
- Exp Mol Med.
- 1999 Jun;31(2):108-114.
ATP-citrate lyase (ACL), an enzyme catalyzing the first step in biosynthesis of fatty acids, is induced during the lipogenesis and cholesterologenesis. We demonstrate that the region -213 to -128 of human ACL... -
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- Different protein-binding patterns in the P3 promoter region of the human insulin-like growth factor II gene in the human liver cirrhosis and hepatocellular carcinoma tissues
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Seo JH, Kim KW, Park BC
- KMID: 1064965
- J Korean Med Sci.
- 1998 Apr;13(2):171-178.
- doi: 10.3346/jkms.1998.13.2.171
The P3 promoter of the human insulin-like growth factor II (IGF-II) is the major IGF-II promoter in fetal liver (FL) and hepatocellular carcinoma (HCC). However, little information is available... -
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- A mechanism of differential expression of GLUT2 in hepatocyte and pancreatic beta-cell line
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Kim JW, Kim YK, Ahn YH
- KMID: 754982
- Exp Mol Med.
- 1998 Mar;30(1):15-20.
DNase I footprinting assay using liver nuclear extracts revealed six protected regions between nucleotide -600 and +110 and hence named Box I-VI. Upstream promoter element (UPE), a DNA element playing crucial role... -
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- Identification of glucocorticoid response element of the rat TRH gene
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Lee GC, Yang IM, Kim BJ, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK
- KMID: 1051555
- Korean J Intern Med.
- 1996 Jun;11(2):138-144.
OBJECTIVES: It was suggested that glucocorticoid exerts cell-specific effects on thyrotropin-releasing hormone (TRH) gene expression at the transcriptional level. Although there is no typical palindromic glucocorticoid response element (GRE) on... -
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