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Role of Reactive Oxygen Species in Hypothalamic Regulation of Energy Metabolism

Diano S

To understand the etiology of metabolic disorders, including obesity and type II diabetes, it is essential to gain better insight into how stored and available energy sources are monitored by...
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Two Cases of Cushing's Disease Due to Large Pituitary ACTH Secreting Tumor

Kim HS, Chung CH, Cho MY, Shin YG, Kim IH, Yang SW, Kim JY

  • KMID: 1853229
  • J Korean Soc Endocrinol.
  • 1998 Mar;13(1):83-93.
Cushing's syndrome that is caused by an adenoma of the corticotrape cells of the anterior pituitay or, rarely, by couticotrope hyperplasia is refered to as Cushing's disease. Cushings disease is...
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A Case of Secondary Trigeminal Neuralgia Caused by Infected Postoperative Maxillary Cyst

Lee SM, Sung HK, Kang JC, Kim HJ

Postoperative maxillary cyst (POMC) is relatively common complication among patients who underwent Caldwell-Luc surgery. Patients with POMC usually have no symptoms, although cyst extension can result in bone destruction or...
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Effect of Geranium Essential Oil on Food Intake via Olfactory Stimulus

Choi SJ, Ye SB, Na HG, Kim GO, Bae CH, Song SY, Kim YW, Park SY, Kim YD

BACKGROUND AND OBJECTIVES: Recently, obesity has become one of the major health problems in our society. To overcome this problem, keeping a balance between food intake and energy expenditure is...
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Effects of Chronic Restraint Stress on Body Weight, Food Intake, and Hypothalamic Gene Expressions in Mice

Jeong JY, Lee DH, Kang SS

BACKGROUND: Stress affects body weight and food intake, but the underlying mechanisms are not well understood. METHODS: We evaluated the changes in body weight and food intake of ICR male mice...
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Intracerebroventricular Injection of Metformin Induces Anorexia in Rats

Lee CK, Choi YJ, Park SY, Kim JY, Won KC, Kim YW

BACKGROUND: Metformin, an oral biguanide insulin-sensitizing agent, is well known to decrease appetite. Although there is evidence that metformin could affect the brain directly, the exact mechanism is not yet...
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Clinical Characteristics of Postoperative Maxillary Cyst

Sharma A, Kim DH, Choi SY, Kim JW, Kwon TG, Paeng JY

PURPOSE: The purpose of this study is to analyze the clinical features of postoperative maxillary cyst (POMC) according to the patient's medical history of previous sinus operation and symptoms with...
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4-hydroxy-3-methoxycinnamic acid regulates orexigenic peptides and hepatic glucose homeostasis through phosphorylation of FoxO1

Kinyua AW, Ko CM, Doan KV, Yang DJ, Huynh MK, Moh SH, Choi YH, Kim KW

4-hydroxy-3-methoxycinnamic acid (ferulic acid, FA) is known to have numerous beneficial health effects, including anti-obesity and anti-hyperglycemic properties. However, the molecular networks that modulate the beneficial FA-induced metabolic effects have...
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Surgical Treatment and Clinical Study of Postoperative Maxillary Cyst

Kwon SH, Yang YS, Min YG

  • KMID: 2274338
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Aug;40(8):1115-1121.
BACKGROUND: Postoperative maxillary cyst(POMC) occurs as a delayed complication following Caldwell-Luc(C-L) operation. Revisional C-L operation has been preferred by most surgeons. Recently, marsupialization with intranasal endoscope has been increased in...
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The effect of radiographic imaging modalities and the observer's experience on postoperative maxillary cyst assessment

Gang TI, Huh KH, Yi WJ, Lee SS, Heo MS, Choi SC

PURPOSE: The purpose of this study was to compare the accuracy of postoperative maxillary cyst (POMC) diagnosis by panoramic radiographs versus computed tomography (CT) and by oral and maxillofacial radiologists...
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The Expression of the alpha-Melanocyte Stimulating Hormone (alpha-MSH) and Melanocortin-1 Receptor (MC1R) in the Epidermis of the Vitiligo

Cha YC, Lee HJ, Lee SJ, Na GY, Chung SL

  • KMID: 2302963
  • Korean J Dermatol.
  • 2003 Jun;41(6):690-695.
BACKGROUND: Vitiligo is a skin disease that is characterized by the loss of cutaneous pigmentation. alpha-Melanocyte stimulating hormone (alpha-MSH) is a neuroimmunomodulating peptide derived from proopiomelanocortin, and melanocortin-1 receptor (MC1R)...
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Udenafil, a Phosphodiesterase 5 Inhibitor, Reduces Body Weight in High-Fat-Fed Mice

Ryu SY, Choi YJ, Park SY, Kim JY, Kim YD, Kim YW

PURPOSE: High-fat (HF) feeding induces hypothalamic leptin resistance via the activation of toll-like receptor 4 (TLR4). TLR4 deficiency confers resistance to diet-induced obesity. Udenafil, an anti-impotence drug, inhibits TLR4 in...
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Improvement of Leptin Resistance

Kim YW

  • KMID: 2320037
  • Yeungnam Univ J Med.
  • 2013 Jun;30(1):4-9.
Leptin, a 16-kDa cytokine, is secreted by adipose tissue in response to the surplus of fat store. Thereby, the brain is informed about the body's energy status. In the hypothalamus,...
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Understanding the Mechanism of Action and Clinical Implications of Anti-Obesity Drugs Recently Approved in Korea

Kim KK

The Korean Ministry of Food and Drug Safety has approved three anti-obesity drugs for long-term management in the past decade. In addition, since 2019, bariatric surgery has been financially supported...
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Usefullness of Ultrasonography in the Evaluation of Postoperative Maxillary Cyst

Jung DH, Cho WH, Hur G, Kim JS, Kim YH, Lee KY

  • KMID: 1614771
  • J Korean Soc Med Ultrasound.
  • 2001 Dec;20(4):321-327.
PURPOSE: The postoperative maxillary cyst (POMC) usually has an anterior wall defect of the maxillary sinus, and this make the evaluation of POMC by ultrasonogrphy. This study was to evaluate...
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Effects of Oxytocin on Cell Proliferation in a Corticotroph Adenoma Cell Line

Lim JS, Eom YW, Lee ES, Kwon HJ, Kwon JY, Choi J, Chung CH, Jo YS, Lee EJ

BACKGROUND: Oxytocin (OXT) has been reported to act as a growth regulator in various tumor cells. However, there is a paucity of data on the influence of OXT on cell...
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Pathophysiology and clinical characteristics of hypothalamic obesity in children and adolescents

Kim JH, Choi JH

The hypothalamus plays a key role in the regulation of body weight by balancing the intake of food, energy expenditure, and body fat stores, as evidenced by the fact that...
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Naloxone Increases the Anorexic Effect of MTII in OLETF Rats

Bae JH, Park YH, Kim SH, Park SY, Kim JY, Son JY, Huh JY, Won KC, Kim YW

BACKGROUND: Leptin, an adipocyte-derived hormone, inhibits obesity in lean subjects, but is not widely used because of leptin resistance. Thus, circumventing the arcuate nucleus of the hypothalamus, the site responsible...
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Acute Effects of Capsaicin on Proopioimelanocortin mRNA Levels in the Arcuate Nucleus of Sprague-Dawley Rats

Lee JS, Kim SG, Kim HK, Baek SY, Kim CM

  • KMID: 2316181
  • Psychiatry Investig.
  • 2012 Jun;9(2):187-190.
OBJECTIVE: Capsaicin, a noxious stimulant and main component of the hot flavor of red peppers, has an analgesic effect when administered to humans. We investigated the expression of proopioimelanocortin (POMC)...
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Antidepressant-like Effect of Kaempferol and Quercitirin, Isolated from Opuntia ficus-indica var. saboten

Park SH, Sim YB, Han PL, Lee JK, Suh HW

Opuntia ficus-indica var. saboten. is widely cultivated in Jeju Island (South Korea) for use in manufacture of health foods. This study described antidepressant effect of two flavonoids (kaempferol and quercitrin)...
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