- Effects of Oxytocin on Cell Proliferation in a Corticotroph Adenoma Cell Line
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Lim JS, Eom YW, Lee ES, Kwon HJ, Kwon JY, Choi J, Chung CH, Jo YS, Lee EJ
- KMID: 2458633
- Endocrinol Metab.
- 2019 Sep;34(3):302-313.
- doi: 10.3803/EnM.2019.34.3.302
BACKGROUND: Oxytocin (OXT) has been reported to act as a growth regulator in various tumor cells. However, there is a paucity of data on the influence of OXT on cell... -
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- Understanding the Mechanism of Action and Clinical Implications of Anti-Obesity Drugs Recently Approved in Korea
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Kim KK
- KMID: 2447082
- Korean J Fam Med.
- 2019 Mar;40(2):63-71.
- doi: 10.4082/kjfm.19.0013
The Korean Ministry of Food and Drug Safety has approved three anti-obesity drugs for long-term management in the past decade. In addition, since 2019, bariatric surgery has been financially supported... -
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- A Case of Secondary Trigeminal Neuralgia Caused by Infected Postoperative Maxillary Cyst
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Lee SM, Sung HK, Kang JC, Kim HJ
- KMID: 2431226
- J Rhinol.
- 2018 Nov;25(2):114-117.
- doi: 10.18787/jr.2018.25.2.114
Postoperative maxillary cyst (POMC) is relatively common complication among patients who underwent Caldwell-Luc surgery. Patients with POMC usually have no symptoms, although cyst extension can result in bone destruction or... -
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- 4-hydroxy-3-methoxycinnamic acid regulates orexigenic peptides and hepatic glucose homeostasis through phosphorylation of FoxO1
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Kinyua AW, Ko CM, Doan KV, Yang DJ, Huynh MK, Moh SH, Choi YH, Kim KW
- KMID: 2440019
- Exp Mol Med.
- 2018 Feb;50(2):e437.
- doi: 10.1038/emm.2017.253
4-hydroxy-3-methoxycinnamic acid (ferulic acid, FA) is known to have numerous beneficial health effects, including anti-obesity and anti-hyperglycemic properties. However, the molecular networks that modulate the beneficial FA-induced metabolic effects have... -
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- Udenafil, a Phosphodiesterase 5 Inhibitor, Reduces Body Weight in High-Fat-Fed Mice
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Ryu SY, Choi YJ, Park SY, Kim JY, Kim YD, Kim YW
- KMID: 2399170
- World J Mens Health.
- 2018 Jan;36(1):41-49.
- doi: 10.5534/wjmh.17028
PURPOSE: High-fat (HF) feeding induces hypothalamic leptin resistance via the activation of toll-like receptor 4 (TLR4). TLR4 deficiency confers resistance to diet-induced obesity. Udenafil, an anti-impotence drug, inhibits TLR4 in... -
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- Clinical Characteristics of Postoperative Maxillary Cyst
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Sharma A, Kim DH, Choi SY, Kim JW, Kwon TG, Paeng JY
- KMID: 2405563
- J Korean Dent Sci.
- 2017 Dec;10(2):60-65.
- doi: 10.5856/JKDS.2017.10.2.60
PURPOSE: The purpose of this study is to analyze the clinical features of postoperative maxillary cyst (POMC) according to the patient's medical history of previous sinus operation and symptoms with... -
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- New Drugs for Obesity Treatment
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Kim WJ, Lee CB
- KMID: 2268868
- Korean J Med.
- 2016 Feb;90(2):121-126.
- doi: 10.3904/kjm.2016.90.2.121
There have recently been many advances in obesity treatment, including lifestyle modifications and pharmacological and surgical treatments. Specifically, pharmacological strategies have improved significantly. However, the history of the development of... -
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- The effect of radiographic imaging modalities and the observer's experience on postoperative maxillary cyst assessment
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Gang TI, Huh KH, Yi WJ, Lee SS, Heo MS, Choi SC
- KMID: 1974499
- Imaging Sci Dent.
- 2014 Dec;44(4):301-305.
- doi: 10.5624/isd.2014.44.4.301
PURPOSE: The purpose of this study was to compare the accuracy of postoperative maxillary cyst (POMC) diagnosis by panoramic radiographs versus computed tomography (CT) and by oral and maxillofacial radiologists... -
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- Pathophysiology and clinical characteristics of hypothalamic obesity in children and adolescents
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Kim JH, Choi JH
- KMID: 2266349
- Ann Pediatr Endocrinol Metab.
- 2013 Dec;18(4):161-167.
- doi: 10.6065/apem.2013.18.4.161
The hypothalamus plays a key role in the regulation of body weight by balancing the intake of food, energy expenditure, and body fat stores, as evidenced by the fact that... -
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- Effects of Chronic Restraint Stress on Body Weight, Food Intake, and Hypothalamic Gene Expressions in Mice
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Jeong JY, Lee DH, Kang SS
- KMID: 2169307
- Endocrinol Metab.
- 2013 Dec;28(4):288-296.
- doi: 10.3803/EnM.2013.28.4.288
BACKGROUND: Stress affects body weight and food intake, but the underlying mechanisms are not well understood. METHODS: We evaluated the changes in body weight and food intake of ICR male mice... -
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- Improvement of Leptin Resistance
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Kim YW
- KMID: 2320037
- Yeungnam Univ J Med.
- 2013 Jun;30(1):4-9.
Leptin, a 16-kDa cytokine, is secreted by adipose tissue in response to the surplus of fat store. Thereby, the brain is informed about the body's energy status. In the hypothalamus,... -
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- Role of Reactive Oxygen Species in Hypothalamic Regulation of Energy Metabolism
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Diano S
- KMID: 1805937
- Endocrinol Metab.
- 2013 Mar;28(1):3-5.
- doi: 10.3803/EnM.2013.28.1.3
To understand the etiology of metabolic disorders, including obesity and type II diabetes, it is essential to gain better insight into how stored and available energy sources are monitored by... -
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- Intracerebroventricular Injection of Metformin Induces Anorexia in Rats
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Lee CK, Choi YJ, Park SY, Kim JY, Won KC, Kim YW
- KMID: 2174427
- Diabetes Metab J.
- 2012 Aug;36(4):293-299.
- doi: 10.4093/dmj.2012.36.4.293
BACKGROUND: Metformin, an oral biguanide insulin-sensitizing agent, is well known to decrease appetite. Although there is evidence that metformin could affect the brain directly, the exact mechanism is not yet... -
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- Acute Effects of Capsaicin on Proopioimelanocortin mRNA Levels in the Arcuate Nucleus of Sprague-Dawley Rats
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Lee JS, Kim SG, Kim HK, Baek SY, Kim CM
- KMID: 2316181
- Psychiatry Investig.
- 2012 Jun;9(2):187-190.
OBJECTIVE: Capsaicin, a noxious stimulant and main component of the hot flavor of red peppers, has an analgesic effect when administered to humans. We investigated the expression of proopioimelanocortin (POMC)... -
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- Effect of Geranium Essential Oil on Food Intake via Olfactory Stimulus
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Choi SJ, Ye SB, Na HG, Kim GO, Bae CH, Song SY, Kim YW, Park SY, Kim YD
- KMID: 2277271
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2011 Nov;54(11):766-770.
- doi: 10.3342/kjorl-hns.2011.54.11.766
BACKGROUND AND OBJECTIVES: Recently, obesity has become one of the major health problems in our society. To overcome this problem, keeping a balance between food intake and energy expenditure is... -
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- Antidepressant-like Effect of Kaempferol and Quercitirin, Isolated from Opuntia ficus-indica var. saboten
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Park SH, Sim YB, Han PL, Lee JK, Suh HW
- KMID: 2165317
- Exp Neurobiol.
- 2010 Jun;19(1):30-38.
- doi: 10.5607/en.2010.19.1.30
Opuntia ficus-indica var. saboten. is widely cultivated in Jeju Island (South Korea) for use in manufacture of health foods. This study described antidepressant effect of two flavonoids (kaempferol and quercitrin)... -
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- The Role of Hypothalamic FoxO1 on Hyperphagia in Streptozotocin-Induced Diabetic Mice
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Nam-Goong , Kim JG, Kim SJ, Hur SJ, Lee JW, Kim ES, Yun CH, Lee BJ, Kim YI
- KMID: 2231144
- Korean Diabetes J.
- 2009 Oct;33(5):375-381.
- doi: 10.4093/kdj.2009.33.5.375
BACKGROUND: Streptozotocin-induced diabetic animals are characterized by hyperphagia due to deficiencies of insulin and leptin. Forkhead box-containing protein of the O subfamily-1 (FoxO1) regulates energy homeostasis by regulating energy expenditure... -
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- Naloxone Increases the Anorexic Effect of MTII in OLETF Rats
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Bae JH, Park YH, Kim SH, Park SY, Kim JY, Son JY, Huh JY, Won KC, Kim YW
- KMID: 2063546
- J Korean Endocr Soc.
- 2008 Feb;23(1):18-26.
- doi: 10.3803/jkes.2008.23.1.18
BACKGROUND: Leptin, an adipocyte-derived hormone, inhibits obesity in lean subjects, but is not widely used because of leptin resistance. Thus, circumventing the arcuate nucleus of the hypothalamus, the site responsible... -
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- Effect of Metformin on the Expression of Nitric Oxide Synthase in High Fat Fed Obese Rats
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Yoon CJ, Jeon WS, Kim YW, Moon KH
- KMID: 2299446
- Korean J Androl.
- 2006 Apr;24(1):44-50.
PURPOSE: Obesity is a well known risk factorfor erectile dysfunction, and metformin normalizes androgen levels in patients with polycystic ovary syndrome and decreases body fat and leptin concentration in normal... -
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- Effects of Intracerebroventricular Infusion of MTII in Monosodium Glutamate(MSG)-obese Rats
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Kwon OJ, Choi DW, Huh JY, Bae JJ, Kim JH, Park YK, Kim JY, Kim YW
- KMID: 2323282
- J Korean Soc Study Obes.
- 2004 Jun;13(2):101-109.
BACKGROUND: Leptin, secreted by adipose tissue, is an afferent signal molecule that contributes to body fat homeostasis through regulation of both food intake and energy expenditure. These effects are mediated... -
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