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Molecular Surveillance of Pfkelch13 and Pfmdr1 Mutations in Plasmodium falciparum Isolates from Southern Thailand

Khammanee , Sawangjaroen N, Buncherd H, Tun AW, Thanapongpichat S

Artemisinin-based combination therapy (ACT) resistance is widespread throughout the Greater Mekong Subregion. This raises concern over the antimalarial treatment in Thailand since it shares borders with Cambodia, Laos, and Myanmar...
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Current Status of Parasite Infections in Indonesia: A Literature Review

Lee J, Ryu JS

Indonesia and South Korea have become inseparable in various respects since the 2 countries established diplomatic relation in 1973. Indonesia is a tropical region that stretches across the equator, comprised...
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Malaria Prevalence in a Low Transmission Area, Jazan District of Southwestern Saudi Arabia

Hawash Y, Ismail K, Alsharif K, Alsanie W

Detailed description of malaria in low transmission areas is crucial for elimination. The current study aimed to provide a comprehensive description for malaria transmission in Jazan, a low transmission district,...
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Mixed Infection with Plasmodium falciparum and Plasmodium ovale in a Returned Traveller: the First Case in Korea

Kim G, Hong HL, Kim SY, Lee HR, Kim DG, Park S, Shin HS, Chin BS, Kim Y

Mixed-species malaria infections are often unrecognized or underestimated. We hereby report the first described case of mixed infection with Plasmodium falciparum and Plasmodium ovale malaria in a returned traveller in...
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Unraveling Haplotype Diversity of the Apical Membrane Antigen-1 Gene in Plasmodium falciparum Populations in Thailand

Lumkul L, Sawaswong , Simpalipan P, Kaewthamasorn M, Harnyuttanakorn P, Pattaradilokrat S

Development of an effective vaccine is critically needed for the prevention of malaria. One of the key antigens for malaria vaccines is the apical membrane antigen 1 (AMA-1) of the...
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An Alternative Method for Extracting Plasmodium DNA from EDTA Whole Blood for Malaria Diagnosis

Seesui K, Imtawil K, Chanetmahun P, Laummaunwai P, Boonmars T

Molecular techniques have been introduced for malaria diagnosis because they offer greater sensitivity and specificity than microscopic examinations. Therefore, DNA isolation methods have been developed for easy preparation and cost...
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Domestic and international trend of vector-borne disease

Bahk HJ, Lee DH

The incidence of vector-borne diseases has increased with climate change and developments of transportation. Malaria was eliminated in the early 1980s in Korea, but one domestic case was reported in...
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Delayed Diagnosis of Falciparum Malaria with Acute Kidney Injury

Choi IH, Hwang PH, Choi SI, Lee DY, Kim MS

Prompt malaria diagnosis is crucial so antimalarial drugs and supportive care can then be rapidly initiated. A 15-year-old boy who had traveled to Africa (South Africa, Kenya, and Nigeria between...
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Antiplasmodial and Cytotoxic Activities of Toad Venoms from Southern Amazon, Brazil

Banfi FF, Guedes KD, Andrighetti CR, Aguiar AC, Debiasi BW, Noronha JD, Rodrigues , Júnior GM, Sanchez BA

The drug-resistance of malaria parasites is the main problem in the disease control. The huge Brazilian biodiversity promotes the search for new compounds, where the animal kingdom is proving to...
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Characteristics of Imported Malaria and Species of Plasmodium Involved in Shandong Province, China (2012-2014)

Xu C, Wei QK, Li J, Xiao T, Yin K, Zhao CL, Wang YB, Kong XL, Zhao GH, Sun H, Liu X, Huang BC

Malaria remains a serious public health problem in Shandong Province, China; therefore, it is important to explore the characteristics of the current malaria prevalence situation in the province. In this...
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Impact of Irrigation Extension on Malaria Transmission in Simret, Tigray, Ethiopia

Chung B

Poor subsistence farmers who live in a semi-arid area of northern Ethiopia build irrigation systems to overcome water shortages. However, there is a high risk of malaria transmission when increased...
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Hemozoin Pigment: An Important Tool for Low Parasitemic Malarial Diagnosis

Mohapatra , Ghosh A, Singh R, Singh DP, Sharma B, Samantaray JC, Deb M, Gaind R

Low parasitemic condition in malaria remains a diagnostic challenge; as the available diagnostic methods failed to detect. Currently, hemozoin (Hz) pigment is gaining attention in the diagnosis of malaria. The...
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Characterization of Pv92, a Novel Merozoite Surface Protein of Plasmodium vivax

Lee SK, Wang B, Han JH, Nyunt MH, Muh F, Chootong P, Ha KS, Park WS, Hong SH, Park JH, Han ET

The discovery and understanding of antigenic proteins are essential for development of a vaccine against malaria. In Plasmodium falciparum, Pf92 have been characterized as a merozoite surface protein, and this...
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Imported Malaria over Fifteen Years in an Inner City Teaching Hospital of Washington DC

Yeruva SL, Sinha A, Sarraf-Yazdy M, Gajjala J

As endemic malaria is not commonly seen in the United States, most of the cases diagnosed and reported are associated with travel to and from the endemic places of malaria....
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Effective High-Throughput Blood Pooling Strategy before DNA Extraction for Detection of Malaria in Low-Transmission Settings

Nyunt MH, Kyaw MP, Thant KZ, Shein T, Han SS, Zaw NN, Han JH, Lee SK, Muh F, Kim JY, Cho SH, Lee SE, Yang EJ, Chang CL, Han ET

In the era of (pre) elimination setting, the prevalence of malaria has been decreasing in most of the previously endemic areas. Therefore, effective cost- and time-saving validated pooling strategy is...
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Anesthetic management of urgent cesarean delivery in a parturient with acute malaria infection: a case report

Zanfini BA, Dell'Anna , Catarci S, Frassanito L, Vagnoni S, Draisci G

Malaria is associated with high rates of morbidity and mortality worldwide, particularly in Africa, Southeast Asia and South America. Nonetheless, several cases of malaria have been reported in Western countries...
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Potential Interaction of Plasmodium falciparum Hsp60 and Calpain

Yeo SJ, Liu DX, Park H

After invasion of red blood cells, malaria matures within the cell by degrading hemoglobin avidly. For enormous protein breakdown in trophozoite stage, many efficient and ordered proteolysis networks have been...
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High Malaria Prevalence among Schoolchildren on Kome Island, Tanzania

Kim MJ, Jung BK, Chai JY, Eom KS, Yong TS, Min DY, Siza JE, Kaatano GM, Kuboza J, Mnyeshi P, Changalucha JM, Ko Y, Chang SY, Rim HJ

In order to determine the status of malaria among schoolchildren on Kome Island (Lake Victoria), near Mwanza, Tanzania, a total of 244 schoolchildren in 10 primary schools were subjected to...
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Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum

Ha YR, Hwang BG, Hong Y, Yang HW, Lee SJ

The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the...
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Allelic Diversity of MSP1 Gene in Plasmodium falciparum from Rural and Urban Areas of Gabon

Mawili-Mboumba DP, Mbondoukwe N, Adande E, Bouyou-Akotet MK

The present study determined and compared the genetic diversity of Plasmodium falciparum strains infecting children living in 2 areas from Gabon with different malaria endemicity. Blood samples were collected from...
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