- Experimental Gastric Non-Balloon Devices
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Choi YI, Kim KO
- KMID: 2427714
- Clin Endosc.
- 2018 Sep;51(5):420-424.
- doi: 10.5946/ce.2018.150
Endoscopic bariatric therapies (EBTs) are promising alternatives to the conventional surgeries used to treat obesity and related metabolic conditions, targeting gastrointestinal anatomical and physiological processes. Many EBTs are at various... -
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- Regulation and function of AMPK in physiology and diseases
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Jeon SM
- KMID: 2361532
- Exp Mol Med.
- 2016 Jul;48(7):e245.
- doi: 10.1038/emm.2016.81
5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an evolutionarily conserved serine/threonine kinase that was originally identified as the key player in maintaining cellular energy homeostasis. Intensive research over the last... -
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- Vitamin D and Immune Responses
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Kang SW
- KMID: 2201988
- J Korean Rheum Assoc.
- 2010 Mar;17(1):16-22.
- doi: 10.4078/jkra.2010.17.1.16
Vitamins and their metabolites are essential for many physiological processes including immune response. In addition to regulating calcium homeostasis, vitamin D exerts various effects on cells of the immune system,... -
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- The molecular mechanism for nuclear transport and its application
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Kim YH, Han ME, Oh SO
- KMID: 2451231
- Anat Cell Biol.
- 2017 Jun;50(2):77-85.
- doi: 10.5115/acb.2017.50.2.77
Transportation between the cytoplasm and the nucleoplasm is critical for many physiological and pathophysiological processes including gene expression, signal transduction, and oncogenesis. So, the molecular mechanism for the transportation needs... -
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- The Migraine-Stroke Connection
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Lee MJ, Lee C, Chung CS
- KMID: 2285608
- J Stroke.
- 2016 May;18(2):146-156.
- doi: 10.5853/jos.2015.01683
Migraine and stroke are common neurovascular disorders which share underlying physiological processes. Increased risks of ischemic stroke, hemorrhagic stroke, and subclinical ischemic lesions have been consistently found in migraineurs. Three... -
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- Metabolic Syndrome and Male Infertility
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Park HJ
- KMID: 2298762
- Korean J Androl.
- 2008 Apr;26(1):1-7.
In recent years, the metabolic syndrome has garnished much attention in Korean population. This condition is multi-faceted and potentially leading to significant disturbance of numerous physiological processes including male reproductive... -
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- Carpal Spasm in a Patient with Hypophosphatemia
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Lee SH, Shim YJ, Choi JH, Kim HS
- KMID: 2093087
- Keimyung Med J.
- 2015 Jun;34(1):39-42.
- doi: 10.0000/kmj.2015.34.1.39
Phosphate is an essential ion and plays a vital role in many physiological processes. Carpopedal spasm is known as a symptom of hypocalcemia, or rarely, hypomagnesemia. We present an unusual... -
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- Neutral Sphingomyelinase and Breast Cancer Research
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Hwang SY, Kim TH, Lee HH
- KMID: 2201018
- J Menopausal Med.
- 2015 Apr;21(1):24-27.
- doi: 10.6118/jmm.2015.21.1.24
Our understanding of the functions of neutral sphingomyelinase (N-SMase) signaling has advanced over the past decade. In this review, we focus on the roles and regulation of N-SMase 1, N-SMase... -
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- Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis
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Purandhar , Jena PK, Prajapati , Rajput P, Seshadri S
- KMID: 2320775
- World J Mens Health.
- 2014 Dec;32(3):123-132.
- doi: 10.5534/wjmh.2014.32.3.123
Heat shock proteins (HSPs) play a role in the homeostasis, apoptosis regulation and the maintenance of the various other physiological processes. Aging is accompanied by a decrease in the resistance... -
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- Neuropeptidomics: Mass Spectrometry-Based Identification and Quantitation of Neuropeptides
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Lee JE
- KMID: 2166535
- Genomics Inform.
- 2016 Mar;14(1):12-19.
- doi: 10.5808/GI.2016.14.1.12
Neuropeptides produced from prohormones by selective action of endopeptidases are vital signaling molecules, playing a critical role in a variety of physiological processes, such as addiction, depression, pain, and circadian... -
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- The Role of Peroxiredoxin Family in Cancer Signaling
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Kim Y, Jang HH
- KMID: 2454666
- J Cancer Prev.
- 2019 Jun;24(2):65-71.
- doi: 10.15430/JCP.2019.24.2.65
Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress by reducing intracellular accumulation of reactive oxygen species (ROS). In mammalian cells, the six Prx isoforms are ubiquitously expressed... -
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- Alcohol and Aging:Neurobiological Effects
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Cheon JS
- KMID: 2333771
- J Korean Geriatr Psychiatry.
- 2000 Jun;4(1):39-49.
The alcohol problems in geriatric population have been strikingly increasing. The age differences of alcohol effect on the brain have been reported by several animal studies. Furthermore, cognitive disorders including... -
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- Clinical Applications of Antioxidants
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Park JH, Kweon GR
- KMID: 2168247
- Hanyang Med Rev.
- 2013 May;33(2):130-136.
- doi: 10.7599/hmr.2013.33.2.130
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are natural by-products of cellular physiological processes involving metabolism of compounds containing oxygen and nitrogen, respectively. Physiological defense mechanisms against ROS/RNS... -
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- Regulation of Iron and Its Significance in Obesity and Complications
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Chan YK, Sung HK, Sweeney G
- KMID: 2271135
- Korean J Obes.
- 2014 Dec;23(4):222-230.
- doi: 10.7570/kjo.2014.23.4.222
Iron is an essential micronutrient with important roles in many critical physiological processes, especially as a structural component of hemoglobin responsible for oxygen transport. Iron homeostasis is tightly regulated, yet... -
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- Circadian Rhythms in Urinary Functions: Possible Roles of Circadian Clocks?
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Noh JY, Han DH, Yoon JA, Kim MH, Kim SE, Ko IG, Kim KH, Kim CJ, Cho S
- KMID: 2232796
- Int Neurourol J.
- 2011 Jun;15(2):64-73.
Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and... -
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- Insights into Hypoxia: Non-invasive Assessment through Imaging Modalities and Its Application in Breast Cancer
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Daimiel I
- KMID: 2450112
- J Breast Cancer.
- 2019 Jun;22(2):155-171.
- doi: 10.4048/jbc.2019.22.e26
Oxygen is crucial to maintain the homeostasis in aerobic cells. Hypoxia is a condition in which cells are deprived of the oxygen supply necessary for their optimum performance. Whereas oxygen... -
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- Distribution and Function of the Bestrophin-1 (Best1) Channel in the Brain
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Oh SJ, Lee CJ
- KMID: 2383780
- Exp Neurobiol.
- 2017 Jun;26(3):113-121.
- doi: 10.5607/en.2017.26.3.113
Bestrophin-1 (Best1) is a calcium-activated anion channel identified from retinal pigment epithelium where human mutations are associated with Best's macular degeneration. Best1 is known to be expressed in a variety... -
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- Evaluation of Saccule Function in Patients with Vitamin D Deficiency
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Talebi H, Moallemi M, Ghorbani M
- KMID: 2438182
- J Audiol Otol.
- 2019 Jan;23(1):49-52.
- doi: 10.7874/jao.2018.00304
BACKGROUND AND OBJECTIVES: Considering important role of vitamin D in many physiological processes including vestibular system in the ear, aim of present study is to evaluate saccule function via cervical... -
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- Novel Concept of a Heart-Gut Axis in the Pathophysiology of Heart Failure
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Kamo T, Akazawa H, Suzuki JI, Komuro I
- KMID: 2389597
- Korean Circ J.
- 2017 Sep;47(5):663-669.
- doi: 10.4070/kcj.2017.0028
Patients with heart failure (HF) have structural and functional changes of the gut as a result of microcirculatory disturbances. A disrupted gut epithelial barrier may lead to translocation of microbial... -
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- Matrix Metallopeptidase 3 Polymorphisms: Emerging genetic Markers in Human Breast Cancer Metastasis
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Suhaimi SA, Chan SC, Rosli R
- KMID: 2470877
- J Breast Cancer.
- 2020 Feb;23(1):1-9.
- doi: 10.4048/jbc.2020.23.e17
Matrix metallopeptidase 3 or MMP3, is a zinc-dependent proteolytic enzyme that is involved in various physiological processes via modification of the extracellular matrix. In particular, its over-expression has been associated... -
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