J Stroke.  2016 May;18(2):146-156. 10.5853/jos.2015.01683.

The Migraine-Stroke Connection

Affiliations
  • 1Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. cspaul@naver.com
  • 2Stroke Center, Heart Vascular Stroke Institute, Samsung Medical Center, Seoul, Korea.

Abstract

Migraine and stroke are common neurovascular disorders which share underlying physiological processes. Increased risks of ischemic stroke, hemorrhagic stroke, and subclinical ischemic lesions have been consistently found in migraineurs. Three possible associations are suggested. One is that underlying pathophysiology of migraine can lead to ischemic stroke. Second, common comorbidities between migraine and stroke can be present. Lastly, some syndromes can manifest with both migraine-like headache and cerebrovascular disease. Future studies should be targeted on bidirectional influence of migraine on different stroke mechanisms and optimal prevention of stroke in migraine patients.

Keyword

Migraine; Ischemic stroke; Hemorrhagic stroke; White matter hyperintensities

MeSH Terms

Cerebrovascular Disorders
Comorbidity
Headache
Humans
Migraine Disorders
Physiological Processes
Stroke
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