- The Role of Oxidative Stress in the Pathogenesis of Asthma
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Cho YS, Moon HB
- KMID: 2133806
- Allergy Asthma Immunol Res.
- 2010 Jul;2(3):183-187.
- doi: 10.4168/aair.2010.2.3.183
Oxidative stress plays a critical role in the pathogenesis of asthma. To effectively control oxidative stress in asthmatics, it is important to investigate the precise intracellular mechanism by which the... -
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- Classification of Peroxiredoxin Subfamilies Using Regular Expressions
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Chon JK, Choi J, Kim SS, Shin W
- KMID: 1572633
- Genomics Inform.
- 2005 Jun;3(2):55-60.
Peroxiredoxins (Prx's) are a superfamily of peroxidases that are ubiquitous in all super-kingdoms. Previous biochemical and structural studies have suggested that Prx's could be divided into five subfamilies (1-Cys, Typical... -
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- The Role of Peroxiredoxin Family in Cancer Signaling
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Kim Y, Jang HH
- KMID: 2454666
- J Cancer Prev.
- 2019 Jun;24(2):65-71.
- doi: 10.15430/JCP.2019.24.2.65
Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress by reducing intracellular accumulation of reactive oxygen species (ROS). In mammalian cells, the six Prx isoforms are ubiquitously expressed... -
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- Characterization of Peroxiredoxins in the Gray matter in the spinal cord after Acute Immobilization Stress
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Paek NH, Kwak SS, Lee DS, Lee YH
- KMID: 2203263
- J Korean Soc Traumatol.
- 2006 Dec;19(2):105-112.
PURPOSE: Many stresses produce reactive oxygen species and bring about mechanism of antioxidant reaction. Cytokine and a neurotransmitter through the cell membrane, as well as signal transduction through the cell membrane, are... -
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- Thyroid and Hydrogen Peroxide
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Park DJ
- KMID: 2168208
- Hanyang Med Rev.
- 2012 Nov;32(4):187-191.
- doi: 10.7599/hmr.2012.32.4.187
The thyroid gland produces high concentrations of hydrogen peroxide (H2O2) which is used for the biosynthesis of the thyroid hormones, triiodothyronine and thyroxine. The most important step in thyroid hormone... -
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- Studies on In Vivo Function of Peroxiredoxins in Knockout Mice
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Yu DY
- KMID: 2168237
- Hanyang Med Rev.
- 2013 May;33(2):97-103.
- doi: 10.7599/hmr.2013.33.2.97
Peroxiredoxins (Prxs) are a family of antioxidant proteins that reduce peroxide levels by using reducing agents such as thioredoxin. These proteins were characterized to have a number of cellular functions,... -
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- Targeting Cellular Antioxidant Enzymes for Treating Atherosclerotic Vascular Disease
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Kang DH, Kang SW
- KMID: 1502509
- Biomol Ther.
- 2013 Mar;21(2):89-96.
Atherosclerotic vascular dysfunction is a chronic inflammatory process that spreads from the fatty streak and foam cells through lesion progression. Therefore, its early diagnosis and prevention is unfeasible. Reactive oxygen... -
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- Analysis of the Expression of Peroxiredoxin I in Human Bladder Cancer
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Kim ET, Sagong H, Kim WJ
- KMID: 2311995
- Korean J Urol.
- 2008 Apr;49(4):300-306.
PURPOSE: Peroxiredoxins(PRDXs) are antioxidant enzymes that play an important role on cell differentiation, proliferation and apoptosis. In this study, we investigated if the expression levels of PRDX I were related... -
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- Expression of peroxiredoxin I regulated by gonadotropins in the rat ovary
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Lee YI, Kang WD, Kim MY, Cho MK, Chun SY
- KMID: 1805484
- Clin Exp Reprod Med.
- 2011 Mar;38(1):18-23.
- doi: 10.5653/cerm.2011.38.1.18
OBJECTIVE: Peroxiredoxins (Prxs) play an important role in regulating cellular differentiation and proliferation in several types of mammalian cells. This report examined the expression of Prx isotype I in the... -
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- Reduced Mitochondrial Properties in Putative Progenitor/Stem Cells of Human Keratinocytes
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Chang SE, Pak YK, Lee HW, Choi JH, Jeong EJ, Choi SH, Chang HW, Chung YS, Kim SY
- KMID: 2156498
- Ann Dermatol.
- 2009 Nov;21(4):364-368.
- doi: 10.5021/ad.2009.21.4.364
BACKGROUND: The characterization of progenitor/keratinocyte stem cells (KSC) remains an unachieved goal. A previous study showed that rapid adhering cells to collagen IV had the characteristics of putative progenitor/KSCs. OBJECTIVE: The... -
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- Selectively Decreased Expression of Peroxiredoxins Induced by Silica in Pulmonary Epithelial Cells
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Lee HL, Kim YS, Park JH, Chung WY, Lee KS, Oh YJ, Sheen SS, Park KJ, Hwang SC
- KMID: 1717945
- Korean J Intern Med.
- 2009 Sep;24(3):220-226.
- doi: 10.3904/kjim.2009.24.3.220
BACKGROUND/AIMS: Peroxiredoxin (Prx) belongs to a ubiquitous family of antioxidant enzymes that regulates many cellular processes through intracellular oxidative signal transduction pathways. Silica-induced lung damage involves reactive oxygen species (ROS)... -
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- Peroxiredoxin I regulates the component expression of gamma-secretase complex causing the Alzheimer's disease
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Lee YJ, Goo JS, Kim JE, Nam SH, Hwang IS, Choi SI, Lee HR, Lee EP, Choi HW, Kim HS, Lee JH, Jung YJ, Kim HJ, Hwang DY
- KMID: 1444961
- Lab Anim Res.
- 2011 Dec;27(4):293-299.
- doi: 10.5625/lar.2011.27.4.293
Peroxiredoxin I (Prx I) is a member of the peroxiredoxins (Prxs) family, which are antioxidant enzymes that regulate various cellular process via intracellular oxidative signal pathways. In order to investigate... -
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- Investigation of Oxidative Stress and Development of Lower Urinary Tract Symptoms in the Urinary Bladder following Partial Bladder Outlet Obstruction by Proteomic Approach
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Shim JH, Kim HJ
- KMID: 2293813
- Korean J Urol.
- 2005 Dec;46(12):1337-1343.
PURPOSE: This study investigated the pathophysiological mechanism using the proteomic approach to detect the marker proteins for the development of lower urinary tract symptoms following a partial bladder outlet obstruction... -
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- Oxidative Inactivation of Peroxiredoxin Isoforms by H2O2 in Pulmonary Epithelial, Macrophage, and other Cell Lines with their Subsequent Regeneration
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Oh YJ, Kim YS, Choi YI, Shin SS, Park JH, Choi YH, Park KJ, Park RW, Hwang SC
- KMID: 2132197
- Tuberc Respir Dis.
- 2005 Jan;58(1):31-42.
- doi: 10.4046/trd.2005.58.1.31
BACKGROUND: Peroxiredoxins (Prxs) are a relatively newly recognized, novel family of peroxidases that reduce H2O2 and alkylhydroperoxide into water and alcohol, respectively. There are 6 known isoforms of Prxs present... -
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- Protective Effects of Peroxiredoxin on Hydrogen Peroxide Induced Oxidative Stress and Apoptosis in Cardiomyocytes
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Park KJ, Kim YJ, Kim J, Kim SM, Lee SY, Bae JW, Hwang KK, Kim DW, Cho MC
- KMID: 2297904
- Korean Circ J.
- 2012 Jan;42(1):23-32.
- doi: 10.4070/kcj.2012.42.1.23
BACKGROUND AND OBJECTIVES: The redox system is an important anti-oxidative system composed of thioredoxin, thioredoxin reductase, and peroxiredoxin (PRx). The fine details of PRx expression and its protective effects in... -
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- Analysis of the Cell Lysate Proteome of a Korean Mycobacterium tuberculosis Isolate K01 with H37Rv and H37Ra Strains
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Ryu SW, Park SC, Bang MN, Han SS, Park YK, Park SN, Shim YS, Kang S, Bai GH
- KMID: 2055002
- J Bacteriol Virol.
- 2004 Jun;34(2):107-112.
Despite recent economic prosperity, Korea still has high prevalence of tuberculosis. Molecular biologic characterization of Korean Mycobacterium tuberculosis strains might provide a deeper understanding of the forces contributing to the... -
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- Preliminary Report of Short-Term Proteomic Changes following Bilateral Oophorectomy in the Female Rat Bladder Tissue
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Kim HJ, Jeong H, Ryu YG
- KMID: 2330534
- J Korean Continence Soc.
- 2006 Dec;10(2):121-125.
PURPOSE: The pathophysiological mechanisms of the bladder dysfunction in postmenopausal state are not well understood especially in moleclular level. Therefore we investigated the changes of bladder in female rat following... -
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- Oxidative stress and the antioxidant enzyme system in the developing brain
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Shim SY, Kim HS
- KMID: 2284280
- Korean J Pediatr.
- 2013 Mar;56(3):107-111.
- doi: 10.3345/kjp.2013.56.3.107
Preterm infants are vulnerable to the oxidative stress due to the production of large amounts of free radicals, antioxidant system insufficiency, and immature oligodendroglial cells. Reactive oxygen species (ROS) play... -
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- Expression of Peroxiredoxin and Thioredoxin in Human Lung Cancer and Paired Normal Lung
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Kim YS, Park JH, Lee HL, Shim JY, Choi YI, Oh YJ, Shin SS, Choi YH, Park KJ, Park RW, Hwang SC
- KMID: 2318648
- Tuberc Respir Dis.
- 2005 Aug;59(2):142-150.
BACKGROUND: Continuous growth stimulation by various factors, as well as chronic oxidative stress, may co-exist in many solid tumors, such as lung cancer. A new family of antioxidant proteins, the... -
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- The Effects of Peroxiredoxin III on Human HeLa Cell Proliferation
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Choi S, Kang S
- KMID: 2054231
- Immune Netw.
- 2003 Dec;3(4):276-280.
- doi: 10.4110/in.2003.3.4.276
BACKGROUND: Peroxidases (Prx) of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol respectively. Hydrogen peroxide is implicated as an intracellular messenger in various cellular responses... -
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