J Korean Soc Traumatol.
2006 Dec;19(2):105-112.
Characterization of Peroxiredoxins in the Gray matter in the spinal cord after Acute Immobilization Stress
- Affiliations
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- 1Department of Surgery, SUN General Hospital, Korea.
- 2College of animal resource science sciences, Kangwon National University, Chunchon, Korea. dslee@kangwon.ac.kr
- 3Department of anatomy, College of Medicine, Chungnam National University, Daejeon, Korea.
Abstract
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PURPOSE: Many stresses produce reactive oxygen species and bring about mechanism of antioxidant reaction.
Cytokine and a neurotransmitter through the cell membrane, as well as signal transduction through the cell membrane,
are used for various pathological condition of the brain, such as neurodegenerative disease. There are several
antioxidant enzymes in cells (superoxcide dismutase, glutathion peroxidasae, peroxiredoxin catalase, etc.)
METHODS
This study used single- or double-label immunohistochemical techniques to analyze mouse spinal neuron cells expressing Prx I and Prx III after acute mobilization stress.
RESULTS
Prx I was observed in dendritic cell of the gray matter of the spinal cord, and Prx III was observed in the cytoplasm of the GM of the spinal cord.
CONCLUSION
The results of this study will help to explain differences of expression in the distributions of the peroxiredoxin enzymes of the spinal cord.
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