- Protective effects of D-005, a lipid extract from Acrocomia crispa fruits, against ischemia/reperfusion-induced acute kidney injury in rats
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Oyarzábal-Yera A, RodrÃguez-Salgueiro S, Merino-GarcÃa N, Ocaña-Nápoles L, González-Núñez L, Mena-Valdés L, Zamora-RodrÃguez Z, Medina-PÃrez JA, Jiménez-Despaigne S, Molina-Cuevas V
- KMID: 2469376
- Kidney Res Clin Pract.
- 2019 Dec;38(4):462-471.
- doi: 10.23876/j.krcp.19.053
BACKGROUND: Acute kidney injury (AKI) induced by renal ischemia/reperfusion (IR) is associated with enhanced production of reactive oxygen species in renal tissues. D-005, a lipid extract obtained from Acrocomia crispa... -
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- Antioxidant and antiobesity activities of oral treatment with ethanol extract from sprout of evening primrose (Oenothera laciniata) in high fat diet-induced obese mice
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Kwak CS, Kim MJ, Kim SG, Park S, Kim IG, Kang HS
- KMID: 2466667
- J Nutr Health.
- 2019 Dec;52(6):529-539.
- doi: 10.4163/jnh.2019.52.6.529
PURPOSE: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL... -
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- Alteration of mitochondrial DNA content modulates antioxidant enzyme expressions and oxidative stress in myoblasts
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Min KH, Lee W
- KMID: 2461045
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):519-528.
- doi: 10.4196/kjpp.2019.23.6.519
Mitochondrial dysfunction is closely associated with reactive oxygen species (ROS) generation and oxidative stress in cells. On the other hand, modulation of the cellular antioxidant defense system by changes in... -
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- Gamma-tocopherol ameliorates hyperglycemia-induced hepatic inflammation associated with NLRP3 inflammasome in alloxan-induced diabetic mice
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Lee H, Lim Y
- KMID: 2464116
- Nutr Res Pract.
- 2019 Oct;13(5):377-383.
- doi: 10.4162/nrp.2019.13.5.377
BACKGROUND/OBJECTIVES: Hyperglycemia-induced hepatic damage has been recognized as one of the major cause of complications in diabetes. Hepatic complications are associated with inflammation and oxidative stress in diabetes. In this... -
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- Antioxidant action of hypoxic conditioned media from adipose-derived stem cells in the hepatic injury of expressing higher reactive oxygen species
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Hong HE, Kim OH, Kwak BJ, Choi HJ, im KH, Ahn J, Kim SJ
- KMID: 2459313
- Ann Surg Treat Res.
- 2019 Oct;97(4):159-167.
- doi: 10.4174/astr.2019.97.4.159
PURPOSE: Almost all liver diseases are known to be accompanied by increased levels of reactive oxygen species (ROS), regardless of the cause of the liver disorder. However, little is known... -
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- Heterologous Expression of Rhizopus Oryzae CYP509C12 Gene in Rhizopus Nigricans Enhances Reactive Oxygen Species Production and 11α-Hydroxylation Rate of 16α, 17-Epoxyprogesterone
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Shen C, Gao X, Li T, Zhang J, Gao Y, Qiu L, Zhang G
- KMID: 2470141
- Mycobiology.
- 2019 Sep;47(3):301-307.
- doi: 10.1080/12298093.2019.1630201
The 11α-hydroxylation of 16α, 17-epoxyprogesterone (EP) catalyzed by Rhizopus nigricans is crucial for the steroid industry. However, lower conversion rate of the biohydroxylation restricts its potential industrial application. The 11α-steroid... -
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- Anti-oxidative Effect of Piperine from Piper nigrum L. in Caenorhabditis elegans
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Park HM, Kim JH, Kim DK
- KMID: 2459969
- Nat Prod Sci.
- 2019 Sep;25(3):255-260.
- doi: 10.20307/nps.2019.25.3.255
Piper nigrum L. (Piperaceae), which is a well-known food seasoning, has been used as a traditional medicine for the treatment of vomiting, abdominal pain, diarrhea and anorexia in Korea, China... -
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- Cyclosporin A aggravates hydrogen peroxide-induced cell death in kidney proximal tubule epithelial cells
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Moon D, Kim J
- KMID: 2459547
- Anat Cell Biol.
- 2019 Sep;52(3):312-323.
- doi: 10.5115/acb.18.192
Cyclosporin A (CsA) does not only exert a toxic effect on kidney parenchymal cells, but also protects them against necrotic cell death by inhibiting opening of mitochondrial permeability transition pore.... -
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- Improvement in histology, enzymatic activity, and redox state of the liver following administration of Cinnamomum zeylanicum bark oil in rats with established hepatotoxicity
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Niknezhad , Sayad-Fathi S, Karimzadeh A, Ghorbani-Anarkooli M, Yousefbeyk F, Nasiri E
- KMID: 2459546
- Anat Cell Biol.
- 2019 Sep;52(3):302-311.
- doi: 10.5115/acb.18.180
Formaldehyde (FA) is an environmentally-available pollutant. Since the liver acts as a detoxifier in the human body, it is the first and most affected organ in individuals exposed to higher-than-normal... -
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- The impact of two doses of coenzyme Q10 on semen parameters and antioxidant status in men with idiopathic oligoasthenoteratozoospermia
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Alahmar AT
- KMID: 2458498
- Clin Exp Reprod Med.
- 2019 Sep;46(3):112-118.
- doi: 10.5653/cerm.2019.00136
OBJECTIVE: Oxidative stress contributes to male infertility, and antioxidants have been recommended for treating idiopathic oligoasthenoteratozoospermia (OAT). There is, however, a lack of agreement on the type, dosing, and use... -
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- Effect of Yeonsan Ogye bioactive peptides on anti-oxidant indexes in rats' liver
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Kim HW, Shim JH, Kim KN
- KMID: 2455855
- J Nutr Health.
- 2019 Aug;52(4):408-411.
- doi: 10.4163/jnh.2019.52.4.408
PURPOSE: This study investigated the effect of bioactive Yeonsan Ogye peptides (YOPs) intake on changes in the hepatic anti-oxidant indexes in male rats. METHODS: Sprague-Dawley male rats were divided into 3... -
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- 7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
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Ko YH, Kim SK, Kwon SH, Seo JY, Lee BR, Kim YJ, Hur KH, Kim SY, Lee SY, Jang CG
- KMID: 2455091
- Biomol Ther.
- 2019 Jul;27(4):363-372.
- doi: 10.4062/biomolther.2018.211
Daidzein isolated from soybean (Glycine max) has been widely studied for its antioxidant and anti-inflammatory activities. However, the protective effects of 7,8,4′-trihydroxyisoflavone (THIF), a major metabolite of daidzein, on 6-hydroxydopamine... -
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- Hepatoprotective effect of sodium hydrosulfide on hepatic encephalopathy in rats
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Kwon KW, Nam Y, Choi WS, Kim TW, Kim GM, Sohn UD
- KMID: 2450493
- Korean J Physiol Pharmacol.
- 2019 Jul;23(4):263-270.
- doi: 10.4196/kjpp.2019.23.4.263
Hydrogen sulfide is well-known to exhibit anti-inflammatory and cytoprotective activities, and also has protective effects in the liver. This study aimed to examine the protective effect of hydrogen sulfide in... -
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- Effect of glycyrrhizin on nicotine-induced behavioral disturbance of planarian, Dugesia japonica
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Kim YJ, So J, Yi YJ, Lee SM
- KMID: 2452873
- J Biomed Transl Res.
- 2019 Jun;20(2):21-29.
- doi: 10.12729/jbtr.2019.20.2.021
Nicotine is a component of tobacco products and is one of the most commonly abused substances that leads to addiction. Therefore, the present study was performed to investigate the behavioral... -
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- Facklamia hominis Isolated from a Wound: A Case Report and Review of the Literature
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Kim TY, Jo J, Kim N, Park H, Roh EY, Yoon JH, Shin S
- KMID: 2450003
- Ann Clin Microbiol.
- 2019 Jun;22(2):50-54.
- doi: 10.5145/ACM.2019.22.2.50
Facklamia hominis is a facultative anaerobic Gram-positive coccus generally displaying weak alpha-hemolysis and negativity for catalase and oxidase. Facklamia species are part of the normal flora of the female genitourinary... -
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- Antioxidant activity of ethanol extract of Lycium barbarum's leaf with removal of chlorophyll
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Kim JE, Bae SM, Nam YR, Bae EY, Ly SY
- KMID: 2466680
- J Nutr Health.
- 2019 Feb;52(1):26-35.
- doi: 10.4163/jnh.2019.52.1.26
PURPOSE: The aim of this study was to estimate the antioxidant activities of 50%, 70%, and 100% ethanol extracts of Lycium barbarum leaf and chlorophyll removal extract. METHODS: The antioxidant activities... -
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- Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice
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Na J, Choi SA, Khan A, Huh JY, Piao L, Hwang I, Ha H, Park YH
- KMID: 2442004
- Biomol Ther.
- 2019 Feb;27(2):134-144.
- doi: 10.4062/biomolther.2018.175
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with the incidence of obesity; however, the underlying mechanisms are unknown. In this study, high-resolution metabolomics (HRM) along with transcriptomics... -
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- A 1:1 exercise-to-rest period ratio needed by animals to restore energy sources and replenish anti-oxidative status after exercise
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Yeom MY, Cho YO
- KMID: 2434072
- Nutr Res Pract.
- 2019 Feb;13(1):17-22.
- doi: 10.4162/nrp.2019.13.1.17
BACKGROUND/OBJECTIVES: Successful recovery of an animal from exercise is essential, especially prior to the next exercise session. This study was conducted to find an effective exercise-to-rest period ratio for the... -
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- Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells
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Jin Y, Baek N, Back S, Myung CS, Heo KS
- KMID: 2452068
- J Bacteriol Virol.
- 2018 Dec;48(4):156-165.
- doi: 10.4167/jbv.2018.48.4.156
Minor ginsenosides Rh1 and Rg2 were isolated from Korean red ginseng and reported to have various biological effects on anti-inflammatory and anti-stress activities. However, the effects of Rh1 and Rg2... -
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- Scratching Stimuli of Mycelia Influence Fruiting Body Production and ROS-Scavenging Gene Expression of Cordyceps militaris
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Liu GQ, Qiu XH, Cao L, Han RC
- KMID: 2434566
- Mycobiology.
- 2018 Dec;46(4):382-387.
- doi: 10.1080/12298093.2018.1544769
The entomopathogenic fungus Cordyceps militaris is a valuable medicinal ascomycete, which degenerates frequently during subsequent culture. To avoid economic losses during industrialized production, scratching stimuli of mycelia was introduced to... -
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