- Molecular Pathology of Lung Cancer: Current Status and Future Directions
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Roh MS
- KMID: 2320538
- Tuberc Respir Dis.
- 2014 Aug;77(2):49-54.
- doi: 10.4046/trd.2014.77.2.49
The rapid development of targeted therapies has enormously changed the clinical management of lung cancer patients over the past decade; therefore, molecular testing, such as epidermal growth factor receptor (EGFR)... -
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- The Utilization of Cytologic Fine-Needle Aspirates of Lung Cancer for Molecular Diagnostic Testing
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Roh MH
- KMID: 2151139
- J Pathol Transl Med.
- 2015 Jul;49(4):300-309.
- doi: 10.4132/jptm.2015.06.16
In this era of precision medicine, our understanding and knowledge of the molecular landscape associated with lung cancer pathogenesis continues to evolve. This information is being increasingly exploited to treat... -
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- Molecular Biologic Techniques in Cytopathologic Diagnosis
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Hwang TS
- KMID: 1472615
- Korean J Pathol.
- 2009 Oct;43(5):387-392.
- doi: 10.4132/KoreanJPathol.2009.43.5.387
Molecular diagnosis is an application of the knowledge on molecular mechanisms of disease to diagnosis, therapeutic decision-making, and prognostication. Basically any molecular diagnostic technique could be used in molecular diagnostic... -
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- Molecular Diagnostics for Detection of Microorganism
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Jang SJ
- KMID: 1610969
- Korean J Clin Microbiol.
- 2003 Mar;6(1):1-6.
No abstract available. -
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- Molecular Testing of Lymphoproliferative Disorders: Current Status and Perspectives
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Jeon YK, Yoon SO, Paik JH, Kim YA, Shin BK, Kim HJ, Cha HJ, Kim JE, Huh J, Ko YH, The Hematopathology Study Group of the Korean Society of Pathologists, The Molecular Pathology Study Group of Korean Society of Pathologists
- KMID: 2392591
- J Pathol Transl Med.
- 2017 May;51(3):224-241.
- doi: 10.4132/jptm.2017.04.09
Molecular pathologic testing plays an important role for the diagnosis, prognostication and decision of treatment strategy in lymphoproliferative disease. Here, we briefly review the molecular tests currently used for lymphoproliferative... -
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- Advances in Understanding the Molecular Biology of Brain Tumors
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Kuo JS, Rutka JT
- KMID: 2010619
- J Korean Neurosurg Soc.
- 2004 Jan;35(1):1-11.
Many advances have been made in understanding the molecular biology of brain tumors through progress in cell and developmental biology. The molecular characterization of rare genetic disorders and tumors shed... -
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- Recent Update in Pathologic Diagnosis for Pancreatic Cystic Neoplasm
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Jang KT
- KMID: 2464972
- Korean J Pancreas Biliary Tract.
- 2019 Oct;24(4):137-140.
- doi: 10.15279/kpba.2019.24.4.137
Pancreas cystic neoplasm is a relatively common disease. However, its' pathologic diagnosis is not easy. The most frequent problem is low cellularity when compared to another organ cytology or biopsy... -
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- Recent Advancement of the Molecular Diagnosis in Pediatric Brain Tumor
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Bae JM, Won JK, Park SH
- KMID: 2417362
- J Korean Neurosurg Soc.
- 2018 May;61(3):376-385.
- doi: 10.3340/jkns.2018.0057
Recent discoveries of brain tumor-related genes and fast advances in genomic testing technologies have led to the era of molecular diagnosis of brain tumor. Molecular profiling of brain tumor became... -
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- Molecular Testing of Lung Cancers
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Shim HS, Choi YL, Kim L, Chang S, Kim WS, Roh MS, Kim TJ, Ha SY, Chung JH, Jang SJ, Lee GK, The Korean Cardiopulmonary Pathology Study Group, The Korean Molecular Pathology Study Group
- KMID: 2392592
- J Pathol Transl Med.
- 2017 May;51(3):242-254.
- doi: 10.4132/jptm.2017.04.10
Targeted therapies guided by molecular diagnostics have become a standard treatment of lung cancer. Epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements are currently used as... -
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- The usefulness of multiple displacement amplification in the molecular studies in Hansen's disease
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Kim JP
- KMID: 2053864
- Korean Lepr Bull.
- 2010 Dec;43(1):3-13.
Appreciable amounts of high-quality DNA are frequently required for use in molecular diagnostic and epidemiology studies. The limited availability of DNA can be a critical obstacle to meeting research and... -
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- Presentation of Progressive Familial Intrahepatic Cholestasis Type 3 Mimicking Wilson Disease: Molecular Genetic Diagnosis and Response to Treatment
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Boga S, Jain D, Schilsky M
- KMID: 2068799
- Pediatr Gastroenterol Hepatol Nutr.
- 2015 Sep;18(3):202-208.
- doi: 10.5223/pghn.2015.18.3.202
Progressive familial intrahepatic cholestasis type 3 (PFIC3) is an autosomal recessive disorder of cholestasis of hepatocellular origin, typically seen in infancy or childhood caused by a defect in the ABCB4... -
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- Recent Advance in Rheumatoid Arthritis
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Ko HJ, Kim HY
- KMID: 2188026
- J Korean Med Assoc.
- 2009 Jul;52(7):657-664.
- doi: 10.5124/jkma.2009.52.7.657
ARheumatoid arthritis is a systemic, inflammatory, autoimmune disorder of unknown origins. Enhanced understanding of molecular pathogenesis has enabled the development of new biologic treatment that focuses on selective parts of... -
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- Syndromic Approach to Parkinson's Disease: Role of Functional Imaging
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Lee CS, Chung SJ, Kim JS
- KMID: 1700740
- J Clin Neurol.
- 2006 Jun;2(2):83-91.
- doi: 10.3988/jcn.2006.2.2.83
Current evidence from monogenic Parkinson's disease (PD) supports the view that PD is a clinical syndrome, rather than a single disease entity, and that the heterogeneity of PD indeed reflects... -
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- PET Imaging-Based Phenotyping as a Predictive Biomarker of Response to Tyrosine Kinase Inhibitor Therapy in Non-small Cell Lung Cancer: Are We There Yet?
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Gerbaudo V, Kim CK
- KMID: 2373450
- Nucl Med Mol Imaging.
- 2017 Mar;51(1):3-10.
- doi: 10.1007/s13139-016-0453-6
The increased understanding of the molecular pathology of different malignancies, especially lung cancer, has directed investigational efforts to center on the identification of different molecular targets and on the development... -
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- Clinical Application of Genetics in Management of Colorectal Cancer
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Kim ER, Kim YH
- KMID: 2174377
- Intest Res.
- 2014 Jul;12(3):184-193.
- doi: 10.5217/ir.2014.12.3.184
The extensive study of genetic alterations in colorectal cancer (CRC) has led to molecular diagnostics playing an increasingly important role in CRC diagnosis and treatment. Currently, it is believed that... -
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- Good Laboratory Standards for Clinical Next-Generation Sequencing Cancer Panel Tests
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Kim J, Park WY, Kim NK, Jang SJ, Chun SM, Sung CO, Choi J, Ko YH, Choi YL, Shim HS, Won JK, The Molecular Pathology Study Group of Korean Society of Pathologists
- KMID: 2392589
- J Pathol Transl Med.
- 2017 May;51(3):191-204.
- doi: 10.4132/jptm.2017.03.14
Next-generation sequencing (NGS) has recently emerged as an essential component of personalized cancer medicine due to its high throughput and low per-base cost. However, no sufficient guidelines for implementing NGS... -
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- Molecular classification of hepatocellular adenoma: A single-center experience
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Shen XY, Hu XG, Kim YB, Kim MN, Hong SY, Kim BW, Wang HJ
- KMID: 2448762
- Ann Hepatobiliary Pancreat Surg.
- 2019 May;23(2):109-114.
- doi: 10.14701/ahbps.2019.23.2.109
BACKGROUNDS/AIMS: Hepatocellular adenoma (HCA) is a rare benign tumor that has a risk of malignant transformation into hepatocellular carcinoma (HCC) and bleeding. The aim of this study was to analyze... -
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- The role of pathologists in multidisciplinary cancer care
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Lee KS, Choe G
- KMID: 2153715
- J Korean Med Assoc.
- 2016 Feb;59(2):108-113.
- doi: 10.5124/jkma.2016.59.2.108
In recent years there has been significant growth in multidisciplinary cancer treatment. In cancer patient management, multidisciplinary cancer treatment is essential for evaluation of treatment response and proper decision making.... -
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- Epidemiology of astrovirus infection in children
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Jeong HS, Jeong A, Cheon DS
- KMID: 2284312
- Korean J Pediatr.
- 2012 Mar;55(3):77-82.
- doi: 10.3345/kjp.2012.55.3.77
Human astrovirus (HAstV) is a major cause of acute diarrhea among children, resulting in outbreaks of diarrhea and occasionally hospitalization. Improved surveillance and application of sensitive molecular diagnostics have further... -
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- Molecular Diagnosis for Personalized Target Therapy in Gastric Cancer
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Cho JY
- KMID: 2372461
- J Gastric Cancer.
- 2013 Sep;13(3):129-135.
Gastric cancer is the second leading cause of cancer-related deaths worldwide. In advanced and metastatic gastric cancer, the conventional chemotherapy with limited efficacy shows an overall survival period of about... -
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