- Artificial intelligence for endoscopy in inflammatory bowel disease
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Takenaka K, Kawamoto A, Okamoto R, Watanabe M, Ohtsuka K
- KMID: 2529562
- Intest Res.
- 2022 Apr;20(2):165-170.
- doi: 10.5217/ir.2021.00079
Inflammatory bowel disease (IBD), with its 2 subtypes, Crohn’s disease and ulcerative colitis, is a complex chronic condition. A precise definition of disease activity and appropriate drug management greatly improve... -
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- Stem cell-based therapy for inflammatory bowel disease
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Shimizu H, Suzuki K, Watanabe M, Okamoto R
- KMID: 2454739
- Intest Res.
- 2019 Jul;17(3):311-316.
- doi: 10.5217/ir.2019.00043
Inflammatory bowel disease (IBD) is an idiopathic, multi-etiological disease characterized by inflammation and mucosal destruction of the gastrointestinal tract. Despite the remarkable advance in immunomodulating therapies, there still remains a... -
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- In Vitro Activities of Panipenem against Clinical Isolates of Aerobic and Anaerobic Bacteria
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Lee K, Lee WH, Yong D, Yum JH, Chong Y, Okamoto R, Inoue M
- KMID: 2285145
- Infect Chemother.
- 2003 Dec;35(6):423-433.
BACKGROUND: Panipenem is a carbapenem antimicrobial agent which has been shown to have broad-spectrum activities against various aerobic and anaerobic bacteria. In this study, in vitro activities of panipenem against... -
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- Why do antimicrobial agents become ineffectual?
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Inoue M, Kuga A, Shimauchi , Yano H, Okamoto R
- KMID: 711591
- Yonsei Med J.
- 1998 Dec;39(6):502-513.
- doi: 10.3349/ymj.1998.39.6.502
Antibiotic resistance has evolved over the past 50 years from a merely microbiological curiosity to a serious medical problem in hospitals all over the world. Resistance has been reported in... -
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- Long-term efficacy and safety of tofacitinib in patients with ulcerative colitis: 3-year results from a real-world study
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Shimizu H, Aonuma Y, Hibiya S, Kawamoto A, Takenaka K, Fujii T, Saito E, Nagahori M, Ohtsuka K, Okamoto R
- KMID: 2558196
- Intest Res.
- 2024 Jul;22(3):369-377.
- doi: 10.5217/ir.2023.00194
Background/Aims: The efficacy and safety of tofacitinib for the treatment of refractory ulcerative colitis (UC) has been demonstrated in clinical trials. Although, a series of reports with real-world evidence of... -
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- Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn’s disease activity confirmed by balloon-assisted enteroscopy
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Kawamoto A, Takenaka K, Hibiya S, Kitazume Y, Shimizu H, Fujii T, Saito E, Ohtsuka K, Okamoto R
- KMID: 2551279
- Intest Res.
- 2024 Jan;22(1):65-74.
- doi: 10.5217/ir.2023.00092
Background/Aims: Endoscopic activity confirmed by enteroscopy is associated with poor clinical outcome in Crohn’s disease (CD). We investigated which of the existing biomarkers best reflects endoscopic activity in CD patients... -
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- Characteristics of Extended-spectrum Beta-lactam Hydrolyzing Activity of Klebsiella pneumoniae and Escherichia coli Strains Isolated from Clinical Specimens
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Chong Y, Lee K, Okamoto R, Inoue M
- KMID: 1548825
- Korean J Infect Dis.
- 1997 Nov;29(6):477-486.
BACKGROUND: Increase in Escherichia coli and Klebsiella pneumoniae isolates with extended- spectrum beta-lactamase (ESBL) have been noted recently in Korea. Current NCCLS disk diffusion test is not sensitive to detect... -
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- Evaluation of bone substitutes for treatment of peri-implant bone defects: biomechanical, histological, and immunohistochemical analyses in the rabbit tibia
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dos Santos PL, de Molon R, Queiroz TP, Okamoto R, de Souza Faloni AP, Gulinelli , Luvizuto E, Garcia IR
- KMID: 2382982
- J Periodontal Implant Sci.
- 2016 Jun;46(3):176-196.
- doi: 10.5051/jpis.2016.46.3.176
PURPOSE: We sought to evaluate the effectiveness of bone substitutes in circumferential peri-implant defects created in the rabbit tibia. METHODS: Thirty rabbits received 45 implants in their left and right tibia.... -
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