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Genetic Structure in the Region Near the Sialidase Gens in Bacteroides fragilis

Kuwahara T, Nakayama H, Iwasa T, Okamoto S, Tsuchihashi Y, Ohnishi Y

  • KMID: 2099356
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):364-364.
No Abstract Available.
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Significance of Peanut Agglutinin in the Differentiation between Nevocellular Nevus and Malignant Melanoma

Chung JY, Moon DC, Kwon KS, Chung TA

  • KMID: 2231256
  • Korean J Dermatol.
  • 1990 Jun;28(3):315-320.
Using peanut agglutinin(PNA), neurarninidase, and avidin-biotin peroxidase com plex(ABC) technique, normal skin specimens, nevocellular nevi, and malignant melanomas were studied, and different PNA binding patterns between nevocellular nevi and malignant...
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Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius

Kim JY, Kim DW, Hwang BS, Woo EE, Lee YJ, Jeong KW, Lee IK, Yun BS

During our ongoing investigation of neuraminidase inhibitors from medicinal fungi, we found that the fruiting bodies of Phellinus igniarius exhibited significant inhibitory activity against neuraminidase from recombinant H3N2 influenza viruses....
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Neuraminidase Inhibitors from the Culture Broth of Phellinus linteus

Yeom JH, Lee IK, Ki DW, Lee MS, Seok SJ, Yun BS

During the search for neuraminidase inhibitors from medicinal fungi, we found that the culture broth of Phellinus linteus exhibited potent inhibitory activity. Solvent partition, Sephadex LH-20 column chromatography, and high-performance...
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Clinical Use of Tamiflu (Oseltamivir)

Chang MS, Woo JH

Oseltamivir (Tamiflu, the trade name) is a neuraminidase inhibitor used for the treatment and prevention of influenza virus infection as well as those of avian influenza infection. The mechanism of...
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Neuraminidase Inhibitors from the Fermentation Broth of Phellinus linteus

Hwang BS, Lee MS, Lee SW, Lee IK, Seo GS, Choi HJ, Yun BS

  • KMID: 2312744
  • Mycobiology.
  • 2014 Jun;42(2):189-192.
During a search for neuraminidase inhibitors derived from medicinal fungi, we found that the fermentation broth of Phellinus linteus exhibited potent neuraminidase inhibitory activity. Through bioassay-guided fractionation, two active compounds...
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Prevention and Treatment of Influenza

Choi YH

Influenza is a disease known to continue to afflict a large number f people and cause many deaths throughout the world. Influenza A and B are the two types of...
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Assessment of hemagglutination activity of porcine deltacoronavirus

Zhang Y, Han L, Xia L, Yuan Y, Hu H

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of...
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Neuraminidase Inhibitors from the Fruiting Body of Glaziella splendens

Kim JY, Woo EE, Ha LS, Ki DW, Lee IK, Yun BS

Neuraminidase (NA) cleaves the glycosidic bond linkages of sialic acids to release the mature virions from infected cells and has been an attractive therapeutic target for anti-influenza agents. In our...
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Acute Hemorrhagic Colitis Associated with the Use of Oseltamivir

Chung DW, Son HS, Park JH, Jung MK, Jeon SW, Cho CM, Kim SK

  • KMID: 2258866
  • Korean J Med.
  • 2011 Jun;80(Suppl 2):S87-S90.
Oseltamivir is a potent selective neuraminidase enzyme inhibitor and effective against nearly all strains of influenza A and B. The importance of treating influenza has been recognized, and oseltamivir has...
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Antiviral Agents Against Influenza Viruses

Park S, Kim JI, Park MS

In annual epidemics and occasional pandemics, influenza viruses cause acute respiratory illnesses in infected humans. Vaccines and antiviral drugs are two main arsenals available for a fight against influenza viruses....
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Effects of beta-toxin of Staphylococcus aureus and Neuraminidase of Streptococcus pneumoniae on Ciliary Activity of Nasal Ciliated Epithelial Cells

Min YG, Kim CS, Rhee CS, Jung IH, Park SW, Kwon TY

  • KMID: 2131743
  • J Rhinol.
  • 1999 Nov;6(2):118-125.
BACKGROUND AND OBJECTIVES: The in vitro effects of pneumococcal neuraminidase and staphylococcal beta-toxin on ciliary activity were investigated at different concentrations and lengths of exposure. MATERIALS AND METHODS: The ciliated...
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Characterization of Hemagglutinin and Neuraminidase Genes and Oseltamivir Resistance of Influenza Viruses Isolated in Korea

Kim YY, Lee JY, Hwang JH, Kim KA, Jang SW, Park MS, Kim WJ, Cho HW, Lee HH, Kang C

  • KMID: 1574119
  • J Bacteriol Virol.
  • 2005 Jun;35(2):149-156.
To investigate the pattern of drug-resistance of human influenza virus (A/H1N1) isolated in Korea during 2001~2002, the sequence analysis of hemagglutinin (HA) and neuraminidase (NA) genes and cell-based assay against...
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Treatment and prophylaxis of influenza

Lee JS

Influenza is an acute respiratory disease caused by the influenza virus. Each year, it causes a significant disease burden, especially in older adults. Furthermore, influenza pandemics occasionally occur because of...
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Immunohistochemical Study of the T-Antigen on the Transitional Cell Carcinoma of the Urinary Bladder

Kim WJ, Kim CW, Kim YK

  • KMID: 2289823
  • Korean J Urol.
  • 1988 Dec;29(6):893-902.
The T-antigen(Thomsen-Friedenreich antigen, T-Ag) has been found in malignant cells but in most normal cells, in which the T-Ag is cryptic but can be unmasked with neuraminidase. The significance of...
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A Case of Polyagglutination due to T Activation

Kim HO, Kim JJ, Choi SS

  • KMID: 2253863
  • Korean J Blood Transfus.
  • 1996 Dec;7(2):263-268.
Red blood cells that agglutinate with most normal adult sera but never with own sera are termed polyagglutinable and can be separated by patterns of lectin reactivity into various types....
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The Diagnosis and Treatment of Influenza

Lee CS

Influenza viruses cause annual epidemics and occasional pandemics that have claimed the millions of lives. On December 4th 2009, more than 207 countries and overseas territories have reported laboratory confirmed...
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Progressive Myoclonus Epilepsy Associated with Macular Cherry-Red Spots

Kang KS, Yun CH, Lee SK

  • KMID: 2343046
  • J Korean Neurol Assoc.
  • 2003 Apr;21(2):204-206.
Myoclonus, generalized epilepsy, and progressive neurological decline characterize progressive myoclonus epilepsy. A 25-year-old woman was admitted for the evaluation of seizure, progressive myoclonus and ataxic gait. Her symptoms had developed...
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The Battle Between Influenza and the Innate Immune Response in the Human Respiratory Tract

Nicholls J

  • KMID: 2391836
  • Infect Chemother.
  • 2013 Mar;45(1):11-21.
Influenza is a viral infection of the respiratory tract. Infection is normally confined to the upper respiratory tract but certain viral strains have evolved the ability to infect the lower...
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Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking

Sahoo M, Jena L, Rath SN, Kumar S

The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for...
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