- Prevalence of Foxp3 Positive T Regulatory Cells is Increased during Progression of Cutaneous Squamous Tumors
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Jang TJ
- KMID: 1782942
- Yonsei Med J.
- 2008 Dec;49(6):942-948.
- doi: 10.3349/ymj.2008.49.6.942
PURPOSE: Forkhead box p3 (Foxp3) positive T regulatory cells (Tregs) have a functionally immunosuppressive property that prevents effector cells from acting against self in autoimmune diseases or a tumor. It... -
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- Efficacy of Dendritic Cells Matured Early with OK-432 (Picibanil(R)), Prostaglandin E2, and Interferon-alpha as a Vaccine for a Hormone Refractory Prostate Cancer Cell Line
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Yoo C, Do HA, Jeong IG, Park H, Hwang JJ, Hong JH, Cho JS, Choo MS, Ahn H, Kim CS
- KMID: 1785906
- J Korean Med Sci.
- 2010 Sep;25(9):1284-1290.
- doi: 10.3346/jkms.2010.25.9.1284
Dendritic cells (DCs) are potent antigen-presenting cells. OK432 (Picibanil(R)) was introduced as a potent stimulator of DC maturation in combination with prostaglandin-E2 and interferon-alpha. We compared the efficacy of a... -
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- Anti-tumor immunostimulatory effect of heat-killed tumor cells
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Yoon TJ, Kim JY, Kim H, Hong C, Lee H, Lee CK, Lee KH, Hong S, Park SH
- KMID: 1103596
- Exp Mol Med.
- 2008 Feb;40(1):130-144.
- doi: 10.3858/emm.2008.40.1.130
As a part of our ongoing search for a safe and efficient anti-tumor vaccine, we attempted to determine whether the molecular nature of certain tumor antigens would influence immune responses... -
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- A monoclonal antibody to common acute lymphoblastic leukemia antigen (CALLA) and its expression on several human tumor cell lines
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Park WS, Hwang TS, Kim TJ, Park CS, Bae YM, Park SH, Lee SK
- KMID: 1421905
- J Korean Med Sci.
- 1992 Jun;7(2):147-153.
- doi: 10.3346/jkms.1992.7.2.147
We describe a newly-made murine monoclonal antibody to the common acute lymphoblastic leukemia antigen (CALLA), named SHB-10. The antigen detected by SHB-10 has a molecular weight of about 105... -
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- Prognostic significance of proliferating cell nuclear antigen-positive growth fraction in gastric adenomas
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Kim WH, Choi GY, Kim YI
- KMID: 1421915
- J Korean Med Sci.
- 1992 Sep;7(3):199-203.
- doi: 10.3346/jkms.1992.7.3.199
The proliferative activity of gastric adenomas from 18 patients (42 endoscopic procedures) was compared with follow-up results. These cases were gastric adenomas proven by follow-up with repeated endoscopic procedures... -
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- Antitumor immunity induced by tumor cells engineered to express a membrane-bound form of IL-2
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Chang MR, Lee WH, Choi JW, Park SO, Paik SG, Kim YS
- KMID: 1056237
- Exp Mol Med.
- 2005 Jun;37(3):240-249.
Transduction of cytokine gene into tumor cells is a promising method of tumor therapy, but the value is limited by accompanying side effects. To focus antitumor immune response to tumor... -
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- Tumor-Specific Immunity Induced by Cryoablation in a Murine Renal Cell Carcinoma Model
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Kim HK, Pyun JH, Cho S, Kang SG, Lee JG, Kim JJ, Cheon J, Park HS, Kang SH
- KMID: 2070099
- Korean J Urol.
- 2014 Dec;55(12):834-840.
- doi: 10.4111/kju.2014.55.12.834
PURPOSE: To evaluate tumor-specific immunity and define the mechanisms involved in the cryoimmunologic response, we compared the tumor control efficacy and immunologic responses of cryoablation with those of surgical excision... -
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- Immunoreactivity of CD99 in Stomach Cancer
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Jung KC, Park WS, Bae YM, Hahn JH, Hahn K, Lee H, Lee HW, Koo HJ, Shin HJ, Shin HS, Park YE, Park SH
- KMID: 1109756
- J Korean Med Sci.
- 2002 Aug;17(4):483-489.
- doi: 10.3346/jkms.2002.17.4.483
CD99 is characteristically expressed in Ewing's sarcoma/primitive neuroectodermal tumor. Recently its immunoreactivity has also been reported in other tumors. However, the significance of CD99 isoforms expressed in these tumors has... -
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- Alterations of HLA class I and class II antigen expressions in borderline, invasive and metastatic ovarian cancers
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Lee YS, Kim TE, Kim BK, Park YG, Kim GM, Jee SB, Ryu KS, Kim IK, Kim JW
- KMID: 1093593
- Exp Mol Med.
- 2002 Mar;34(1):18-26.
In an effort to understand whether HLA class I and II plays any role in the process of tumorigenesis and metastasis, we have immunohistochemically examined expression of HLA class I... -
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- Presence of autocrine hepatocyte growth factor-Met signaling and its role in proliferation and migration of SNU-484 gastric cancer cell line
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Park M, Park H, Kim WH, Cho H, Lee JH
- KMID: 1056234
- Exp Mol Med.
- 2005 Jun;37(3):213-219.
Autocrine stimulation via coexpression of hepatocyte growth factor (HGF) and its receptor (Met) has been reported in many human sarcomas, but few in carcinomas. In this report, we found that... -
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- The Comparison of Cytotoxic T-Lymphocyte Effects of Dendritic Cells Stimulated by the Folate Binding Protein Peptide Cultured with IL-15 and IL-2 in Solid Tumor
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Kim DK, Kim JH, Kim YT, Kim JW, Ioannides
- KMID: 1093943
- Yonsei Med J.
- 2002 Dec;43(6):691-700.
- doi: 10.3349/ymj.2002.43.6.691
The current modalities for treating cancer employ not only single but multiple approaches involving surgery, radiotherapy and chemotherapy. Unfortunately, the survival outcome is not promising even with these approaches. Alternative... -
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- Alterations of HLA class I and II antigen expression in preinvasive, invasive and metastatic cervical cancers
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Ryu KS, Lee YS, Kim BK, Park YG, Kim YW, Hur SY, Kim TE, Kim IK, Kim JW
- KMID: 938877
- Exp Mol Med.
- 2001 Sep;33(3):136-144.
HLA expression is altered in a large variety of human cancers. We performed immunohistochemical staining on tissues from normal, preinvasive, invasive and metastatic cervical cancer tissues using anti-HLA class I... -
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- Natural killer activity and antibody-dependent cellular cytotoxicity in patients with primary lung cancer
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Kim SK, Cho CH, Ahn CM, Jang SH, Lee YH, Kim SK, Chang J, Lee BK, Kim SJ, Youn JK
- KMID: 1117763
- Yonsei Med J.
- 1992 Mar;33(1):41-47.
- doi: 10.3349/ymj.1992.33.1.41
The NK activity and ADCC of peripheral blood mononuclear cell were examined to evaluate the contribution of ADCC and NK activity to host immune response against lung cancer. The NK... -
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- Cell-mediated immunity in patients with invasive carcinoma of the cervix
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Park TK, Kim SN
- KMID: 693177
- Yonsei Med J.
- 1989 Jun;30(2):164-172.
- doi: 10.3349/ymj.1989.30.2.164
Multiple in vitro immune parameters were investigated in thirty-four untreated patients with invasive carcinoma of the cervix and in twenty-five controls. The parameters measured were percentages and absolute counts of... -
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- Identification of Pancreatic Cancer-Associated Tumor Antigen from HSP-Enriched Tumor Lysate-Pulsed Human Dendritic Cells
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Kim HS, Kang D, Moon MH, Kim HJ
- KMID: 2130828
- Yonsei Med J.
- 2014 Jul;55(4):1014-1027.
- doi: 10.3349/ymj.2014.55.4.1014
PURPOSE: Vaccine strategies utilizing dendritic cells (DCs) to elicit anti-tumor immunity are the subject of intense research. Although we have shown that DCs pulsed with heat-treated tumor lysate (HTL) induced... -
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- Carcinoma ex Pleomorphic Adenoma of the Salivary Glands: Distinct Clinicopathologic Features and Immunoprofiles Between Subgroups According to Cellular Differentiation
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Kim JW, Kwon GY, Roh JL, Choi SH, Nam SY, Kim SY, Cho KJ
- KMID: 1785983
- J Korean Med Sci.
- 2011 Oct;26(10):1277-1285.
- doi: 10.3346/jkms.2011.26.10.1277
In carcinoma ex pleomorphic adenoma (CXPA), pleomorphic adenoma (PA) and diverse carcinoma components showing luminal (ductal) or non-luminal (myoepithelial) differentiation coexist. To elucidate the clinicopathological implications of cellular differentiation in... -
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