- Ectopic Over-expression of Oncogene Pim-2 Induce Malignant Transformation of Nontumorous Human Liver Cell Line L02
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Ren K, Duan W, Shi Y, Li B, Liu Z, Gong J
- KMID: 1792950
- J Korean Med Sci.
- 2010 Jul;25(7):1017-1023.
- doi: 10.3346/jkms.2010.25.7.1017
In order to prove that ectopic over-expression of Pim-2 could induce malignant transformation of human liver cell line L02, three groups of cells were set up including human liver cell... -
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- Very-Late Onset Diffuse Large B-cell Lymphoma with CD3 Coexpression in a Kidney Transplant Patient
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Kim B, Chung S, Kang SH, Cho SG, Park CW, Chang YS
- KMID: 2142015
- Korean J Nephrol.
- 2011 Nov;30(6):689-693.
B-lineage non-Hodgkin lymphoma may aberrantly coexpress T-cell markers. In general population, however, cases of diffuse large B-cell lymphomas with CD3 co-expression are rare because the CD3 marker is the most... -
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- Active Immunization Using Dendritic Cells Mixed With Tumor Cells Inhibits The Growth Of Lymphomas
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Park J, Suh C, Yang J, Park JS, Park KU, Min YJ, Kim HJ, Kim YH, Kim SH
- KMID: 2157653
- J Korean Med Sci.
- 2003 Jun;18(3):372-380.
- doi: 10.3346/jkms.2003.18.3.372
Dendritic cells (DCs) are potent antigen-presenting cells for the induction and activation of cytotoxic T lymphocytes. We tested whether bone marrow derived DCs are capable of inducing protective immunity against... -
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- Relationship between Melanogenicity and Malignancy in Malignant Melanoma Cells
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Kim HI, Youn JK, Park YK
- KMID: 1729569
- Yonsei Med J.
- 1988 Dec;29(4):357-366.
- doi: 10.3349/ymj.1988.29.4.357
Though the malignancy of a tumor is generally postulated to be affected by the degree of differentiation of tumor cells, the relationship between differentiation and malignancy of tumors has... -
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- Glioma Stem Cell-Targeted Dendritic Cells as a Tumor Vaccine Against Malignant Glioma
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Ji B, Chen Q, Liu B, Wu L, Tian D, Guo Z, Yi W
- KMID: 1776923
- Yonsei Med J.
- 2013 Jan;54(1):92-100.
- doi: 10.3349/ymj.2013.54.1.92
PURPOSE: Cancer stem cells have recently been thought to be closely related to tumor development and reoccurrence. It may be a promising way to cure malignant glioma by using glioma... -
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- Dendrotoxin-kappa suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice
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Jang SH, Ryu PD, Lee SY
- KMID: 1067335
- J Vet Sci.
- 2011 Mar;12(1):35-40.
- doi: 10.4142/jvs.2011.12.1.35
Voltage-gated K+ (Kv) channels have been considered to be a regulator of membrane potential and neuronal excitability. Recently, accumulated evidence has indicated that several Kv channel subtypes contribute to the... -
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- Antitumor Activity of TRAIL Recombinant Adenovirus in Human Malignant Glioma Cells
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Kim KU, Seo SY, Heo KY, Yoo YH, Kim HJ, Lee HS, Choi SS, Hwang TH, Lee HJ
- KMID: 2157760
- J Korean Med Sci.
- 2005 Dec;20(6):1046-1052.
- doi: 10.3346/jkms.2005.20.6.1046
Tumor necrosis factor-Related Apoptosis-Inducing Ligand (TRAIL) has been reported to specifically kill malignant cells but to be relatively nontoxic to normal cells. One of disadvantages to previous in vivo protocols... -
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- Behavioral Characteristics of a Mouse Model of Cancer Pain
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Lee BH, Seong J, Kim UJ, Won R, Kim J
- KMID: 1734052
- Yonsei Med J.
- 2005 Apr;46(2):252-259.
- doi: 10.3349/ymj.2005.46.2.252
Pain is a major symptom in cancer patients, and most cancer patients with advanced or terminal cancers suffer from chronic pain related to treatment failure and/or tumor progression. In the... -
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- Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinoma cells
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Cho KH, Lee HS, Ku SK
- KMID: 1102948
- J Vet Sci.
- 2008 Mar;9(1):9-14.
- doi: 10.4142/jvs.2008.9.1.9
The density of intestinal endocrine cells, in Balb/c mice with colon 26 (CT-26) carcinoma cells, were examined immunohistochemically at 28 days after implantation. After CT-26 cell administration there was a... -
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- Tumor-Specific Immunity Induced by Cryoablation in a Murine Renal Cell Carcinoma Model
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Kim HK, Pyun JH, Cho S, Kang SG, Lee JG, Kim JJ, Cheon J, Park HS, Kang SH
- KMID: 2070099
- Korean J Urol.
- 2014 Dec;55(12):834-840.
- doi: 10.4111/kju.2014.55.12.834
PURPOSE: To evaluate tumor-specific immunity and define the mechanisms involved in the cryoimmunologic response, we compared the tumor control efficacy and immunologic responses of cryoablation with those of surgical excision... -
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- Increased uptake of 99mTc-HMPAO in necrotic brain tumors
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Lee SH, Choi CW, Kim JH, Rhee CH, Lim SM
- KMID: 645214
- J Korean Med Sci.
- 1998 Oct;13(5):529-532.
- doi: 10.3346/jkms.1998.13.5.529
99mTc complex of hexamethylpropylene amine oxime (99mTc-HMPAO), which has been used as a tracer for regional cerebral blood flow (rCBF), has been shown to localize in primary brain tumors... -
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- Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity
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Hu J, Chen LJ, Liu L, Chen X, Chen PL, Yang G, Hou WL, Tang MH, Zhang F, Wang XH, Zhao X, Wei YQ
- KMID: 1072942
- Exp Mol Med.
- 2008 Dec;40(6):617-628.
- doi: 10.3858/emm.2008.40.6.617
Honokiol is an active compound purified from magnolia that has been shown to induce cell differentiation, apoptosis, and anti-angiogenesis effects, as well as an enhancement in tumor growth delay in... -
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- Suppression of Tumor Formation and Induction of Natural Killer Cell Activity in BALB/c Nude Mice by Human B7-1 (CD80) Gene Transfer Subcutaneously Injected with Human Hepatocellular Carcinoma Cells (Huh-7)
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Yoon SK, Kim TG, Cho HI, Lee BS, Cho SH, Han NI, Lee YS, Jang JW, Chung KW, Sun HS, Kim BS
- KMID: 863146
- Korean J Hepatol.
- 2003 Jun;9(2):124-134.
BACKGROUND/AIMS: Immunogene therapy is extensively studied for a therapeutic modality of various cancers. This study was conducted to investigate the efficacy of immunogene therapy using the T-cell costimulatory molecule... -
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- Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer
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Sung HY, Yang SD, Park AK, Ju W, Ahn JH
- KMID: 2374185
- Yonsei Med J.
- 2017 Jan;58(1):27-34.
- doi: 10.3349/ymj.2017.58.1.27
PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12... -
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- Adenovirus-mediated p53 tumor suppressor gene therapy against subcutaneous HuH7 hepatoma cell line nodule of nude mice
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Choi JY, Park YM, Byun BH, Kim BS, Hong EG, Shin DY, Seong YR, Im DS
- KMID: 646305
- J Korean Med Sci.
- 1999 Jun;14(3):271-276.
- doi: 10.3346/jkms.1999.14.3.271
Mutations of the tumor-suppressor gene p53 have been found in 30-50% cases of hepatocellular carcinoma (HCC). In this study, E1-negative adenoviral vector encoding wild-type p53 under the control of the... -
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- Bystander-Mediated Regression of Murine Neuroblastoma via Retroviral Transfer of the HSV-TK Gene
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Cho HS, Lee HR, Kim MK
- KMID: 1785703
- J Korean Med Sci.
- 2004 Feb;19(1):107-112.
- doi: 10.3346/jkms.2004.19.1.107
Selective introduction of genes conferring chemosensitivity into proliferating tumor cells may be used to treat cancer. We investigated the bystander effect of retrovirusmediated gene transfer of herpes simplex virus thymidine... -
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- Folate Receptor Targeted Imaging Using Poly (ethylene glycol)-folate: In Vitro and In Vivo Studies
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Kim SL, Jeong HJ, Kim EM, Lee CM, Kwon TH, Sohn MH
- KMID: 1778345
- J Korean Med Sci.
- 2007 Jun;22(3):405-411.
- doi: 10.3346/jkms.2007.22.3.405
The aim of this study was to ascertain the folate receptor (FR) targetability by an in vitro study and to acquire FR-targeted images in vivo models by using synthetic folate... -
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- Changes of gastrointestinal argyrophil endocrine cells in the COLO205 tumor-implanted Balb/c-nu/nu mice
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Ku SK, Seong SK, Lee HS, Lee JH
- KMID: 1090758
- J Vet Sci.
- 2005 Dec;6(4):267-271.
The regional distributions and frequencies of argyrophil endocrine cells in gastrointestinal (GI) tract of Balb/c-nu/ nu mouse were studied using Grimelius silver stain after abdominal subcutaneous implantation of COLO205. The... -
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- Administration of multiple cytokine genes with anti-tumor activity inhibits both tumor incidence and tumor growth
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Jang HS, Cho TH, Jang YS, Choung PH
- KMID: 711662
- Yonsei Med J.
- 1999 Aug;40(4):355-362.
- doi: 10.3349/ymj.1999.40.4.355
The finding of reporter gene expression in muscle cells after intramuscular injection of a reporter gene containing DNA has suggested that injection of a certain gene in its... -
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- Retroviral-mediated IL-2 gene transfer into murine neuroblastoma
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Cho HS, Song JY, Park CY, Lyu CJ, Kim BS, Kim KY
- KMID: 1060275
- Yonsei Med J.
- 2000 Feb;41(1):76-81.
- doi: 10.3349/ymj.2000.41.1.76
We used retroviral-mediated gene transfer of the human interleukin (IL)-2 gene into murine neuroblastoma cells to investigate whether locally-secreted IL-2 is able to influence the generation of anti-tumor immune responses.... -
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