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A Role of Natural Killer T Cells for the Pathogenesis of Asthma

  • KMID: 2299584
  • Korean J Asthma Allergy Clin Immunol.
  • 2008 Jun;28(2):89-95.
No abstract available.
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Innate immunity in asthma

Kim HY

Asthma is a complex and heterogeneous disease with several phenotypes. Most studies have focused on allergic asthma associated with allergen sensitization and adaptive immunity. On the other hand, nonallergic asthma...
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Unusual Suspects in the Development of Obesity-Induced Inflammation and Insulin Resistance: NK cells, iNKT cells, and ILCs

Bonamichi , Lee J

The notion that obesity-induced inflammation mediates the development of insulin resistance in animal models and humans has been gaining strong support. It has also been shown that immune cells in...
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A Case of Natural Killer T-cell Lymphoma of the Tongue

Cho SG, Lee DH, Kim HR, Cho KJ

  • KMID: 2276199
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Aug;47(8):783-786.
Malignant lymphoma, which represents about 5.4% of all neoplasms and more significantly 19-28% of malignant neoplasms, is the most common non-epithelial malignancy in the head and neck area and non-Hodgkin's...
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Intracellular Bacterial Infection and Invariant NKT Cells

Emoto M, Emoto Y

The invariant (i) natural killer (NK)T cells represent a unique subset of T lymphocytes which express the V alpha14 chain of the T cell receptor (TCR), that recognizes glycolipid antigens...
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Lineage Differentiation Program of Invariant Natural Killer T Cells

Kwon DI, Lee YJ

Invariant natural killer T (iNKT) cells are innate T cells restricted by CD1d molecules. They are positively selected in the thymic cortex and migrate to the medullary area, in which...
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Increased Th2-like Invariant Natural Killer T cells in Peripheral Blood From Patients With Asthma

Shim JU, Koh YI

PURPOSE: Invariant natural killer T (iNKT) cells might play an important role in asthma pathogenesis in humans. Our previous study found no difference in the number of blood iNKT cells...
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Natural killer T cell and pathophysiology of asthma

Jang GC

Natural killer T (NKT) cell is a special type of T lymphocytes that has both receptor of natural killer (NK) cell (NK1.1, CD161c) and T cell (TCR) and express a...
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Natural Killer T-cell Lymphoma Presented With Ophthalmoplegia

Kim JH, Park MS, Lee SJ

  • KMID: 2343355
  • J Korean Neurol Assoc.
  • 2009 Feb;27(1):54-57.
Natural killer/T-cell lymphoma (NKTL) usually involves the nasal cavity or paranasal sinuses during the initial stage, and may invade the orbit or brain in the advanced phase. Thus, most patients...
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Expansion and Sub-Classification of T Cell-Dependent Antibody Responses to Encompass the Role of Innate-Like T Cells in Antibody Responses

Park C, Kim TJ

In addition to T cell-dependent (TD) Ab responses, T cells can also regulate T cell-independent (TI) B cell responses in the absence of a specific major histocompatibility complex (MHC) class...
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The Development of NKT Cells in Thymus is Defective in CD45 Knockout Mice

Jung DH, Margulies

  • KMID: 1573065
  • Korean J Immunol.
  • 2000 Sep;22(3):117-121.
No abstract available.
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Comparison of Invariant NKT Cells with Conventional T Cells by Using Gene Set Enrichment Analysis (GSEA)

Oh SJ, Ahn JY, Chung DH

BACKGROUND: Invariant Natural killer T (iNKT) cells, a distinct subset of CD1d-restricted T cells with invariant Valphabeta TCR, functionally bridge innate and adaptive immunity. While iNKT cells share features with...
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Novel Role of Invariant Natural Killer T-cell in Glycemic Control: Regulation by human Adenovirus 36

Park S, Nam JH

Obesity is associated with a state of chronic low-grade inflammation. This abnormal inflammation state may cause metabolic dysfunction. Many studies have supported the claim that immune cells such as adipose...
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Epstein-Barr Virus-Associated Vesiculopapular Eruption on the Face of a Patient with Natural Killer T Cell Lymphoma

Lim JS, Kim TM, Cho KH

Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are...
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TLR4, 5, and 9 Agonists Inhibit Murine Airway Invariant Natural Killer T Cells in an IL-12-Dependent Manner

Shim JU, Rhee JH, Koh YI

PURPOSE: Invariant natural killer T (iNKT) cells may play an important role in the pathogenesis of asthma in mice and humans. Thus, an agent that modulates the function of iNKT...
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The Roles of Innate Lymphoid Cells in the Development of Asthma

Woo Y, Jeong D, Chung DH, Kim HY

Asthma is a common pulmonary disease with several different forms. The most studied form of asthma is the allergic form, which is mainly related to the function of Th2 cells...
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Deficiencies of Circulating Mucosal-associated Invariant T Cells and Natural Killer T Cells in Patients with Acute Cholecystitis

Kim JC, Jin HM, Cho YN, Kwon YS, Kee SJ, Park YW

Mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells are known to play crucial roles in a variety of diseases, including autoimmunity, infectious diseases, and cancers. However, little...
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The presence of CD8+ invariant NKT cells in mice

Lee H, Hong C, Shin J, Oh S, Jung S, Park YK, Hong S, Lee GR, Park SH

Invariant natural killer T (iNKT) cells develop in the thymus upon recognition of CD1d expressed on developing thymocytes. Although CD4 and CD8 coreceptors are not directly involved in the interaction...
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Natural Killer T Cells in Acute and Unmedicated Patients with Major Depressive Disorder

Park EJ, Lee JH, Lee KH, Han SI, Jeon YW

  • KMID: 2341176
  • J Korean Neuropsychiatr Assoc.
  • 2006 May;45(3):208-213.
OBJECTIVES: To evaluate an association between depression and altered immunity, we examined peripheral T lymphocyte or natural killer (NK) cell measures plasma ACTH and cortisol using the flow cytometry in...
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Deficiencies of Circulating Mucosal-associated Invariant T Cells and Natural Killer T Cells in Patients with Multiple Trauma

Jo YG, Choi HJ, Kim JC, Cho YN, Kang JH, Jin HM, Kee SJ, Park YW

Mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells are known to play important roles in autoimmunity, infectious diseases and cancers. However, little is known about the roles...
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