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Comparison of Collecting Methods of Nasal Fluids Using Albumin after Nasal Provocation in Allergic Patients

Kim YH, Jang TY, Kim JE, Lim DW, Kim KS

BACKGROUND AND OBJECTIVES: Although different methods of collecting nasal fluid exist and can influence the result of the study, there have not been any studies made yet to compare the...
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The Usefulness as a Specific Marker of Blood and Nasal Lavage Fluid YKL-40 in Allergic Rhinitis Patients

Park DS, Lee YJ, Lim J, Yoo SW, Nam GS, Lee JH

BACKGROUND AND OBJECTIVES: Chitin is a recognition element for tissue infiltration by innate cells implicated in allergy and asthma. Chitinases are characterized by the ability to cleave chitin. YKL-40, the...
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Increased vascular permeability and reduced neutral endopeptidase activity in rat nasal mucosa after ozone exposure

Kim YM, Jung BJ, Kim BK, Rha KS

  • KMID: 2275671
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jun;44(6):611-615.
BACKGROUND AND OBJECTIVES: Exposure to ozone has several effects on the respiratory tract, including airway inflammation and hyperresponsiveness. It has been suggested that these were associated with decreased NEP...
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Effects of Corticosteroid on Expression of IL-18 in the Airway Mucosa of Allergic Rhinitis Mouse Model

Kim SW, Jeon YK, Hong SC, Won TB, Kim YM, Rhee CS, Min YG

  • KMID: 2131883
  • J Rhinol.
  • 2006 Nov;13(2):101-106.
Background: This study aimed to investigate the release and response of IL-18 to steroid treatment in the allergic rhinitis (AR) mouse model. MATERIALS AND METHODS: BALB/c mice were sensitized systematically...
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Effects of Nasal Instillation of Staphylococcal Enterotoxin B on Nasal and Bronchial Mucosa in BALB/c Mouse

Jin SY, Kim EH, Lee GH, Park YK, Kim YM, Rha KS

  • KMID: 2297606
  • J Rhinol.
  • 2011 May;18(1):35-42.
BACKGROUND AND OBJECTIVES: The effect of nasal exposure to staphylococcal enterotoxin in the pathogenesis of allergic rhinitis remains controversial. We sought to determine the effect of increasing doses of intranasally...
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Anti-Allergic Effects of Aloe Glycoprotein (NY945) on Ovalbumin-Induced Airway Allergy in the Guinea Pig

Yun JB, Seong WJ, Chung MH, Min YG

  • KMID: 2131795
  • J Rhinol.
  • 2002 Nov;9(1, 2):16-23.
BACKGROUND AND OBJECTIVES: Aloe is one of the well known substances to decrease inflammation and promote wound healing. Although little is known about its mechanism, recent studies suggest that aloe...
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An Intratracheal Challenge Murine Model of Asthma: Can Bronchial Inflammation Affect the Nose?

Xie J, Xi Y, Zhang Q, Chen G, Wei L, Lai K, Zhong N

PURPOSE: Extensive data support the influence of the upper airway on lower airway inflammation and pathophysiology in allergic disease. However, few studies have focused on allergic inflammation in the nose...
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The Comparative Study of Mucociliary Clearance with Long-term Hypertonic Saline versus Normal Saline Nasal Wash of Normal Person and Patients after Endoscopic Sinus Surgery

Roh HJ, Youn SH, Kwak DH, Lee GS, Moon HS, Kim SW, Lee JD

  • KMID: 1874418
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Oct;43(10):1067-1072.
BACKGROUND AND OBJECTIVES: Nasal irrigation, a conventional therapy for both surgical and nonsurgical patients with a history of chronic rhinosinusitis, aids in the clearance of secretions, debris, and intranasal crusts....
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Airway Remodeling in Mice with Experimentally Induced Airway Allergy

Kim HS, Kim DH, Park JY, Choi JW, Kim YM, Rha KS

  • KMID: 2297666
  • J Rhinol.
  • 2007 Nov;14(2):92-99.
BACKGROUND AND OBJECTIVES: Allergic rhinitis and asthma display many similarities in their epithelial and inflammatory responses to allergens. However, one notable difference is that disruption and desquamation of the epithelium...
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Repeated Ozone Exposure Induces Th2 Immune Responses in Mice

Jin YD, Park YK, Kim YM, Park SW, Rha KS, Park CI

  • KMID: 2297689
  • J Rhinol.
  • 2005 May;12(1):16-20.
BACKGROUND AND OBJECTIVES: It has been reported that ozone exposure exacerbate allergic rhinitis symptoms and may contribute to increase allergic rhinitis prevalence. However, a causal relationship still remained unsolved. The...
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Recent update of local allergic rhinitis

Cho SH

Rhinitis is a common airway disease that can affect patient's quality of life and social activities. Rhinitis comprises heterogenous diseases and classified as allergic rhinitis (AR) or nonallergic rhinitis (NAR)...
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Effects of Ebselen on Ozone-Induced Nasal Mucosal Inflammation in Mice

Yoo MS, Jin YD, Park YK, Min IK, Park SW, Rha KS, Park CI

  • KMID: 2276386
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Apr;48(4):460-465.
BACKGROUND AND OBJECTIVES: Although the mechanism of ozone-induced airway inflammation and hyperresponsiveness is largely unknown, NO and peroxynitrite has been suggested to be associated with it. Ebselen, a seleno-organic compound,...
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Effects of Nasal Instillation of Staphylococcal Enterotoxin B on Allergic Inflammation in Mice

Kim YM, Kim EH, Park CH, Yoon YH, Kim JM, Rha KS

BACKGROUND AND OBJECTIVES: The role of Staphylococcus aureus enterotoxin B (SEB) in allergic rhinitis remains controversial. We used a mouse model of airway allergy to determine the effects of nasal...
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Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis

Wee JH, Zhang YL, Rhee CS, Kim DY

PURPOSE: It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment of allergic rhinitis (AR). This study aimed to evaluate the effect...
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Changes of Alpha1-Antitrypsin Levels in Allergen-induced Nasal Inflammation

Shin SY, Choi GS, Lee KH, Kim SW, Won KY, Lee JH, Cho JS, Park HS

  • KMID: 2166459
  • Clin Exp Otorhinolaryngol.
  • 2011 Mar;4(1):33-39.
OBJECTIVES: Alpha1-antitrypsin (AAT) is the main inhibitor of human neutrophil elastase, and plays a role in counteracting the tissue damage caused by elastase in local inflammatory conditions. The study evaluated...
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Effects of Repeated Ozone Exposure on Airway Remodeling in Mice

Kim YM, Kim IJ, Kim HS, Kim AY, Han WK, Rha KS

  • KMID: 2012382
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Mar;51(3):240-249.
BACKGROUND AND OBJECTIVES: To investigate whether repeated long-term exposure of ozone has an effect on airway remodeling and whether ozone exposure has an aggravating effect on airway remodeling during allergen...
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The Effect of Nano-Silver on Allergic Rhinitis Model in Mice

Shin SH, Ye MK

OBJECTIVES: Silver has long been known as a strong antimicrobial and disinfectant. Several types of nano-silver coated products have been developed. However, the antimicrobial and disinfectant characteristics of nano-silver have...
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Effect of ozone on nasal allergic responses in ovalbumin-sensitized rats

Ju IH, Kim YM, Jung BJ, Kim HY, Park CI, Rha KS

  • KMID: 2285893
  • J Asthma Allergy Clin Immunol.
  • 2002 Jun;22(2):418-426.
Background and objectives: A large body of evidence suggests that ozone plays an important role in the development of respiratory allergy. However, the mechanisms by which ozone may interact with...
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Investigation of the antiallergic activity of olopatadine on rhinitis induced by intranasal instillation of antigen in sensitized rats using thermography

Tamura T

BACKGROUND: The main symptoms of allergic rhinitis (AR) are sneezing, rhinorrhea and nasal obstruction. It was reported that the nasal skin temperature after intranasal administration of histamine or grass pollen...
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The Effects of Intranasal Instillation of Stem Cell Factor in Mice with Experimentally-Induced Allergic Rhinitis

Min YG, Oh SJ, Kim JW, Lee SS, Lee CH, Rhee CS, Jin JW

  • KMID: 2275994
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Feb;46(2):110-114.
BACKGROUND AND OBJECTIVES: The pathogenesis of allergic rhinitis has not been fully understood. The role of stem cell factor (SCF) in allergic airway inflammation has recently been identified. This study...
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