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A Comparison of Epidural Morphine and Nalbuphine for Post - operative Pain Control

Kim JS, Lee KW, Song KS, Park KH, Kim KS

This study was performed to compare the effects of epidural morphine and nalbuphine with general anesthesia for relief of pain after abdominal surgery. Patients were devided into three groups like...
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Postoperative Analgesia by Caudal Nalbuphine HCL

Shin JS, Yoon DM, Lee KM, Oh HK

  • KMID: 2200364
  • J Korean Pain Soc.
  • 1990 Jun;3(1):44-50.
Epidural injection of narcotics for postoperative pain relief has been well reported. Caudal nalbuphine was assessed as a postoperative analgesic in a randomized double blind study of 80 patients after...
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Epidural Nalbuphine Hydrochloride for Postoperative Pain Relief

Ham BM, Lee SC

A number of recent reports have described the usefulness of the epidural injection of narcotics for the relief of postoperative pain. But the epidural use of narcotic agonist-antagonist, nalbuphine hydrochloride,...
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The Effect of Intravenous Injection of Nalbuphine HCL and Morphine on the CO2 Response Curve in Normal Volunteers

Ham BM, Lee YS

To compare the respiratory depressant effect of nalbuphine and morphine, six healthy male volunteers (mean age 26 yr) were given the nalbuphine at a dose of 0.15 mg/kg and morphine...
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A Effectiveness of Butorphanol and Nalbuphine as Utilized with Ketorolac in Patient Controlled Analgesia after Total Abdominal Hysterectomy

Kim DH, Park CH

  • KMID: 2425678
  • J Korean Pain Soc.
  • 1998 Oct;11(2):263-267.
BACKGROUND: This study was designed to know the dose requirement, analgesic efficacy and side effects of butorphanol and nalbuphine when administered with ketorolac by patient controlled analgesia (PCA) after total abdominal hysterectomy. METHODS:...
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Cardiovascular Effects of Verapamil during Nalbuphine - Nitrous Oxide Anesthesia

Chung JK, Kim JM, Kim SS, Lee JK, Cheun JK

Cardiovascualar effects of a verapamil infusion were investigated in six dogs given nalbuphine-nitrous anesthesia. Verapamil 0.2 mg/kg was given followed by an infusion of 3 and 6 mcg/kg per minute....
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A Case of Withdrawal Symptom after Injection of Nalbuphine in a Chronically Morphine-Dependent Patient

Cho KT, Lee SC, Yum KW, Kim SK, Kim DH

Nalbuphine, a mixed agonist-antagonist type opioid, can precipitate abstinence syndrome in opioid-dependent patients especially in large doses. We can prevent this syndrome by avoiding the injection of agonist-antagonist type opioid...
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MAC of Enflurane Nalbuphine-Enflurane and ED50 of Fentanyl under 65% N20 in Rats

Oh JG, Lee WH, Kim HJ

  • KMID: 1946491
  • J Korean Pain Soc.
  • 1994 Nov;7(2):181-187.
The MAC (ED50)values of enflurane, fentanyl, and nalbuphine-enflurane under 65% N2O were determined in 76 Sprague-Dawley rats using the tail-clamp technique to compare the equipotent effects of intravenous and inhaled...
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The Compatibility of Mixed Solutions of Ketorolac Tromethamine with Nalbuphine HCl

Hahm TS, Kim JA, Lee SM

BACKGROUND: In patient-controlled analgesia (PCA), ketorolac tromethamine has been mixed with nalbuphine HCL in the same PCA balloon or syringe. The compatibility of mixed drugs is an important factor in...
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A Comparison of Nalbuphine, Morphine and Placebo as Premedication Agents

Lee HW, Kim JH, Kang PS, Lim HJ, Chae BK, Chang SH, Shin JS

Nalbuphine hydrochloride is a new analgesic structurally related to naloxone, a widely used narotic antagonist, and oxymorphone, a potent narcotic analgesic. Multiple clinical trials have verified the efficacy of nalbuphine...
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A comparison of the Analgesic and Side Effects of Epidural Morphine and Nalbuphine-Morphine Mixture in Post-Cesarean Section Patients

Lee YW, Lee JW, Yoon DM, Oh HK

  • KMID: 1748736
  • J Korean Pain Soc.
  • 1992 Nov;5(2):221-228.
The effect of epidural nalbuphine on pruritus, nausea, vomiting, voiding difficulties and/or analgesia induced by epidural morphine was determined in sixty Cesarian delivery patients. They were physical status l or...
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Comparison of Midazolam with and without Nalbuphine for Intravenous Sedation in Nasal Surgery

Jeon EJ, Park YS, Lee SK, Lee SE, Jang Y

  • KMID: 2276464
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Aug;48(8):1008-1013.
BACKGROUND AND OBJECTIVES: Effective and safe premedication in nasal surgery is very important in nasal surgery under local anesthesia. We investigated the effects of preoperative administration of midazolam only and...
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The effects of nalbuphine and fentanyl on experimental spinal cord injuries

Lee WH

Opiate receptor agonists (especially dynorphin - a kappa receptor agonist) have found to increase in the injuried segment of spinal cord. It is known to cause spinal cord damage when...
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Analgesic Effects of Intraperitoneal Morphine, Nalbuphine, and Ketorolac on the Formalin Test in Rats

Hong JY, Lee YW, Lee YS, Nam YT

BACKGROUND: The antinociceptive effect and the potency of systemically administered morphine (micro-agonist), nalbuphine (agonist-antagonist), and ketorolac (cyclooxygenase inhibitor) was examined in rats using the formalin test. METHODS: Male Sprague-Dawley rats...
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A Comparison of the Analgesic and Side Effects of Continuous Epidural Morphine and Nalbuphine for Postoperative Pain

Jeon SY, Lee SH, Kwon BY

BACKGROUND: A number of recent reports have described the usefulness of the epidural injection of narcotics for the relief of postoperative pain. Morphine, a u-receptor agonist, produce strong analgesic effect...
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The Effects of Intravenous Nalbuphine on the Posttonsillectomy Pain in Children

Jo DH, Park JG, Kim MH

  • KMID: 2425675
  • J Korean Pain Soc.
  • 1998 Oct;11(2):247-252.
BACKGROUND: Tonsillectomy is one of the most common operation in children. Postoperative pain and its sequelae are universal complaints of the patients. The purpose of this study was to evaluate the effects...
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Effects of propofol and nalbuphine on emergence agitation after sevoflurane anesthesia in children for strabismus surgery

Kim HJ, Kim HS, Kim SD, Kim CS, Kim JT, Lee KJ, Park SJ

BACKGROUND: Emergence agitation in children is frequently associated with sevoflurane general anesthesia. We measured the effects of propofol and nalbuphine on emergence agitation after sevoflurane anesthesia in children for strabismus...
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A Comparison of Analgesic Effects and Side Effects of Intrathecal Morphine, Nalbuphine and a Morphine-Nalbuphine Mixture for Pain Relief during a Cesarean Section

Yoon HJ, Jee YS, Hong JY

BACKGROUND: The purpose of this study was to find additional effects of intrathecal nalbuphine 1 mg to morphine 0.1 mg for pain relief during a cesarean section. METHODS: Sixty...
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Epidural Nalbuphine Reduces the Side Effects from Epidural Morphine after Cesarean Section

Ahn JC, Lee SK, Han IS, Jang SC

BACKGROUND: This study was undertaken to reduce the side effects of epidural morphine through the addition of nalbuphine in 37 cesarean delivery. METHODS: Forty patients were divided into 2 groups; M(control)...
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The preemptive analgesic effect of nalbuphine in pediatric adenoidectomy or tonsillectomy

Park KS, Byun HJ, Kim JT, Kim HS

  • KMID: 1803588
  • Anesth Pain Med.
  • 2010 Oct;5(4):343-346.
BACKGROUND: The effectiveness of preemptive analgesia is still controversial. This study was designed to compare the effects of nalbuphine used in the pre-anesthesia period and after surgery for pain control...
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