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Establishment and Characterization of Multipotent Germ Line Stem Cells (MGSCs) from Neonatal Mouse Testis

Han SC, Song H, Jun JH

  • KMID: 1483347
  • Korean J Reprod Med.
  • 2008 Mar;35(1):39-48.
OBJECTIVE: The aim of this study was to investigate whether multipotent germline stem cells (MGSCs) can be established from neonatal mouse testis. METHODS: Various cells containing MGSCs were collected from neonatal...
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The Efficient Gene Delivery into Human Mesenchymal Stem Cells Using Retroviral Vectors

Kim SS, Kim BJ, Kim HS

  • KMID: 2092807
  • Korean J Anat.
  • 2003 Oct;36(5):381-387.
Human mesenchymal stem cells (hMSCs) are multipotent stem cells that can differentiate into several mesenchymal lineage cells. In this study, we established an efficient method for gene delivery into these...
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Establishment of a Method for Cryopreservation of Neural Stem Cells

Kwon KW, Kim MR, Kim HS, Lee YD, Kim SS

  • KMID: 2092846
  • Korean J Anat.
  • 2004 Dec;37(6):499-508.
Neural stem cells are multipotent stem cells that can differentiate into neurons and glial cells. Neural stem cells are found in not only developing nervous system but some restricted regions...
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Establishment of a Multipotent Neural Stem Cell Line from the Adult Mouse Cerebrum

Kim KS, Choi YS, Seo SY, Kim BH, Kim YS, Lee MC

  • KMID: 2322928
  • J Korean Soc Spine Surg.
  • 2006 Dec;13(4):225-233.
STUDY DESIGN: Establishment of a multipotent neural stem cell line from the adult mouse cerebrum. OBJECTIVES: To establish a daughter cell line, B2A1, from B2 cells through the limiting dilution method,...
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Isolation, Characterization and Growth Kinetic Comparison of Bone Marrow and Adipose Tissue Mesenchymal Stem Cells of Guinea Pig

Aliborzi G, Vahdati A, Mehrabani , Hosseini S, Tamadon A

BACKGROUND: Mesenchymal stem cells (MSCs) from different sources have different characteristics. Moreover, MSCs are not isolated and characterized in Guinea pig for animal model of cell therapy. AIM OF THE WORK:...
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A Simple Method to Isolate and Expand Human Umbilical Cord Derived Mesenchymal Stem Cells: Using Explant Method and Umbilical Cord Blood Serum

Hassan G, Kasem I, Soukkarieh C, Aljamali M

BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are multipotent stem cells that can be isolated from umbilical cords and are therapeutically used because of their ability to differentiate into various...
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Differentiation and characteristics of undifferentiated mesenchymal stem cells originating from adult premolar periodontal ligaments

Kim SS, Kwon DW, Im I, Kim YD, Hwang DS, Holliday L, Donatelli , Son WS, Jun ES

OBJECTIVE: The purpose of this study was to investigate the isolation and characterization of multipotent human periodontal ligament (PDL) stem cells and to assess their ability to differentiate into bone,...
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A Case of Childhood Essential Thrombocythemia

Lee JE, Lee YJ, Huh JH, Lee KS

  • KMID: 2072486
  • Korean J Pediatr Hematol Oncol.
  • 1999 Apr;6(1):141-145.
Essential thrombocythemia in childhood is a rare clonal myeloproliferative disorder in the multipotent stem cell origin and is associated with an increased risk of thrombohemorrhagic complications. The one of...
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Transcriptional regulatory networks underlying the reprogramming of spermatogonial stem cells to multipotent stem cells

Jeong HS, Bhin J, Kim HJ, Hwang D, Lee DR, Kim KS

Spermatogonial stem cells (SSCs) are germline stem cells located along the basement membrane of seminiferous tubules in testes. Recently, SSCs were shown to be reprogrammed into multipotent SSCs (mSSCs). However,...
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Effects of Basic Fibroblast Growth Factor on Proliferation of Human Mesenchymal Stem cells

Kim SS, Choi JW, Kwack KB, Lee YD, Kim HS

  • KMID: 2092847
  • Korean J Anat.
  • 2004 Dec;37(6):509-517.
Human mesenchymal stem cells (hMSCs) are multipotent stem cells that can differentiate into several mesenchymal lineage cells. In this study, we established conditions that allowed a long term expansion of...
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Roles of Mesenchymal Stem Cells in Tissue Regeneration and Immunomodulation

Ayala-Cuellar AP, Kang JH, Jeung EB, Choi KC

Mesenchymal stem cells are classified as multipotent stem cells, due to their capability to transdifferentiate into various lineages that develop from mesoderm. Their popular appeal as cell-based therapy was initially...
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Effect of subcutaneous treatment with human umbilical cord blood-derived multipotent stem cells on peripheral neuropathic pain in rats

Lee MJ, Yoon TG, Kang M, Kim HJ, Kang KS

In this study, we aim to determine the in vivo effect of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs) on neuropathic pain, using three, principal peripheral neuropathic pain models....
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The Cell Survival and Differentiation after Transplantation, Which Harvest from Adult Rat Brain by High-speed Centrifugation Method

Kim JT, Yoo DS, Woo JH, Huh PW, Cho KS, Kim DS

  • KMID: 1956341
  • J Korean Neurosurg Soc.
  • 2005 Aug;38(2):121-125.
OBJECTIVE: Many recent reports have shown that the mature mammalian brain harbors multipotent stem cells, rendering the brain capable of generating new neurons and glia throughout life. Harvested stem cells...
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Long Term Exposure to Myrtucommulone-A Changes CD105 Expression and Differentiation Potential of Mesenchymal Stem Cells

Izgi K, Sonmez MF, Canatan H, Iskender B

Mesenchymal stem cells (MSCs) represent a heterogeneous group of multipotent stem cells that could be found in various somatic tissues. MSCs are defined by molecular and functional features including spindle-shape...
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The Involvement of Multipotential Progenitor Cells in Mooren's Ulcer

Lee IG, Ye J, Kim JC

The aim of this study was to assess the involvement of multipotential progenitor cells in the pathogenesis of Mooren's ulcer using immunohistochemical staining techniques. Tissue specimens were collected from 3...
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Extensive characterization of feline intra-abdominal adipose-derived mesenchymal stem cells

Kim HR, Lee J, Byeon JS, Gu NY, Lee J, Cho IS, Cha SH

Mesenchymal stem cells (MSCs) isolated from various tissues have been well characterized for therapeutic application to clinical diseases. However, in contrast to MSCs from other animal species, the characteristics of...
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Characterization of Peripheral Blood CD34+ Cells Mobilized by Recombinant Human Granulocyte-Colony Stimulating Factor in Healthy Adult Donors

Byun JR, Chung IJ, Kwon SY, Seo JS, Choi KS, Park MR, Lee JJ, Kim HJ

  • KMID: 1849145
  • Korean J Hematol.
  • 1998 Oct;33(3):411-420.
BACKGROUND: CD34+ cells are capable of engraftment and hematopoietic reconstitution. However, expression patterns of other surface antigens such as CD13, CD33, CD38 and HLA-DR on CD34+ cells in mobilized peripheral...
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Isolation and Identification of Respiratory Cells from Human Amniotic Fluid

Kim EJ, Park YW, Kim YH, Kim YS, Oh JT

  • KMID: 1475792
  • J Korean Assoc Pediatr Surg.
  • 2009 Jun;15(1):1-10.
Recently, amniotic fluid has gained attention as one of the potential sources for cell therapy and tissue engineering because it has characteristics of multipotent stem cells. However, current knowledge about...
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Leukemia propagating cells in Philadelphia chromosome-positive ALL: a resistant phenotype with an adverse prognosis

El-Menshawy N, Abd-Aziz S, Elkhamisy , Ebrahim MA

BACKGROUND: Targeted therapy has revolutionized the management of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL); however, relapse still occurs because of the presence of quiescent stem cells, termed leukemia propagating...
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Eosinophil Development, Regulation of Eosinophil-Specific Genes, and Role of Eosinophils in the Pathogenesis of Asthma

Uhm TG, Kim BS, Chung IY

Eosinophils arise from hematopoietic CD34+ stem cells in the bone marrow. They acquire IL-5Ralpha on their surface at a very early stage during eosinophilopoiesis, and differentiate under the strong influence...
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