- Pancreatic Cancer and MicroRNAs
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Hwang JH
- KMID: 1792843
- Korean J Gastroenterol.
- 2012 Jun;59(6):395-400.
- doi: 10.4166/kjg.2012.59.6.395
MicroRNAs (miRNAs) are recently discovered non-coding small RNAs that play a role as regulators of genetic expressions in eukaryotic cells. It comprises about 20 nucleotides, which contains seed sequence to... -
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- Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155
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Lee HJ, Lee EJ, Seo M
- KMID: 2466377
- Yonsei Med J.
- 2016 Jan;57(1):247-253.
- doi: 10.3349/ymj.2016.57.1.247
PURPOSE: Apoptosis of vascular endothelial cells is a type of endothelial damage that is associated with the pathogenesis of cardiovascular diseases such as atherosclerosis. Heterotrimeric GTP-binding proteins (G proteins), including... -
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- Different MicroRNA Expression Levels in Gastric Cancer Depending on Helicobacter pylori Infection
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Chang H, Kim N, Park JH, Nam RH, Choi YJ, Lee HS, Yoon H, Shin CM, Park YS, Kim JM, Lee DH
- KMID: 2380763
- Gut Liver.
- 2015 Mar;9(2):188-196.
- doi: 10.5009/gnl13371
BACKGROUND/AIMS: This study was conducted to identify microRNAs (miRNAs) that are differentially expressed in Helicobacter pylori-infected patients with an intestinal type of gastric cancer using miRNA microarray and to confirm... -
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- Emodin prevents intima thickness via Wnt4/Dvl-1/beta-catenin signaling pathway mediated by miR-126 in balloon-injured carotid artery rats
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Hua JY, He YZ, Xu Y, Jiang XH, Ye W, Pan ZM
- KMID: 2155424
- Exp Mol Med.
- 2015 Jun;47(6):e170.
- doi: 10.1038/emm.2015.36
Neointimal proliferation after vascular injury is a key mechanism of restenosis, a major cause of percutaneous transluminal angioplasty failure and artery bypass occlusion. Emodin, an anthraquinone with multiple physiological activities,... -
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- Suppression of MicroRNA let-7a Expression by Agmatine Regulates Neural Stem Cell Differentiation
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Song J, Oh Y, Kim JY, Cho KJ, Lee JE
- KMID: 2427165
- Yonsei Med J.
- 2016 Nov;57(6):1461-1467.
- doi: 10.3349/ymj.2016.57.6.1461
PURPOSE: Neural stem cells (NSCs) effectively reverse some severe central nervous system (CNS) disorders, due to their ability to differentiate into neurons. Agmatine, a biogenic amine, has cellular protective effects... -
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- Expression of MicroRNA in Host Cells Infected with Helicobacter pylori
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Chung JW, Jeong SH, Lee SM, Pak JH, Lee GH, Jeong JY, Kim JH
- KMID: 2412213
- Gut Liver.
- 2017 May;11(3):392-400.
- doi: 10.5009/gnl16265
BACKGROUND/AIMS: MicroRNAs (miRNAs) regulate gene expression. We assess miRNA regulation by Helicobacter pylori infection and elucidate their role in H. pylori-infected gastric epithelial cells. METHODS: The relationship between miRNA expression and... -
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- miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor
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Tak H, Kim J, Jayabalan , Lee H, Kang H, Cho DH, Ohn T, Nam SW, Kim W, Lee EK
- KMID: 2155388
- Exp Mol Med.
- 2014 Nov;46(11):e123.
- doi: 10.1038/emm.2014.73
Mitochondrial morphology is dynamically regulated by forming small, fragmented units or interconnected networks, and this is a pivotal process that is used to maintain mitochondrial homeostasis. Although dysregulation of mitochondrial... -
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- MicroRNA-200c as a Prognostic Biomarker for Pancreatic Cancer
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Paik WH, Song BJ, Kim HW, Kim HR, Hwang JH
- KMID: 2373344
- Korean J Gastroenterol.
- 2015 Oct;66(4):215-220.
- doi: 10.4166/kjg.2015.66.4.215
BACKGROUND/AIMS: MicroRNA (miRNA) regulates messenger RNA stability and translation. In cancer biology, miRNA affects the growth and metastasis of cancer cells by controlling epithelial-mesenchymal transition (EMT). MiR-200 family (200a/200b/200c/141) and... -
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- Dicer Is Down-regulated and Correlated with Drosha in Idiopathic Sudden Sensorineural Hearing Loss
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Kim S, Lee JH, Nam SI
- KMID: 2164515
- J Korean Med Sci.
- 2015 Aug;30(8):1183-1188.
- doi: 10.3346/jkms.2015.30.8.1183
Previously, we reported the expression levels of specific microRNA machinery components, DGCR8 and AGO2, and their clinical association in patients with idiopathic sudden hearing loss (SSNHL). In the present study,... -
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- Down-regulated serum microRNA-101 is associated with aggressive progression and poor prognosis of cervical cancer
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Jiang W, Pan JJ, Deng YH, Liang MR, Yao LH
- KMID: 2413201
- J Gynecol Oncol.
- 2017 Nov;28(6):e75.
- doi: 10.3802/jgo.2017.28.e75
OBJECTIVE: MicroRNAs (miRNAs) play a vital role in pathogenesis and progression of many cancers, including cervical cancer. However, importance of serum level of miR-101 in cervical cancer has rarely been... -
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- Survival of hypoxic human mesenchymal stem cells is enhanced by a positive feedback loop involving miR-210 and hypoxia-inducible factor 1
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Chang W, Lee CY, Park JH, Park MS, Maeng LS, Yoon CS, Lee MY, Hwang KC, Chung YA
- KMID: 1482815
- J Vet Sci.
- 2013 Mar;14(1):69-76.
- doi: 10.4142/jvs.2013.14.1.69
The use of mesenchymal stem cells (MSCs) has emerged as a potential new treatment for myocardial infarction. However, the poor viability of MSCs after transplantation critically limits the efficacy of... -
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