- Bacterial 23S Ribosomal RNA, a Ligand for Toll-like Receptor 13
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Manzoor Z, Koh YS
- KMID: 2168672
- J Bacteriol Virol.
- 2012 Dec;42(4):357-358.
- doi: 10.4167/jbv.2012.42.4.357
Toll-like receptors are required for detection of pathogen-associated molecular patterns and play critical roles in protection of host from infection. Murine TLR13 was recently reported to be involved in recognition... -
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- Caspase-11, the Main Executioner in Non-canonical Inflammasome
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Manzoor Z, Koh YS
- KMID: 1717688
- J Bacteriol Virol.
- 2012 Jun;42(2):169-171.
- doi: 10.4167/jbv.2012.42.2.169
Murine caspase-11 is orthologus to human caspase-4 and caspase-5, and is required for the response to cholera toxin B and infection with Escherichia coli, Citrobacter rodentium or Vibrio cholerae. Caspase-11... -
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- A20 Protects Against Arthritis by Regulation of the NLRP3 Inflammasome
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Manzoor Z, Koh YS
- KMID: 2068744
- J Bacteriol Virol.
- 2015 Sep;45(3):282-284.
- doi: 10.4167/jbv.2015.45.3.282
Rheumatoid arthritis is an autoinflammatory disease that primarily affects joints and is characterized by pervasive joint inflammation. A20/Tumor necrosis factor, alpha-induced protein 3 (Tnfaip3) inhibits activation of nuclear factor kappa-light-chain-enhancer... -
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- cGAS-cGAMP Signaling and Antiviral Defense
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Manzoor Z, Koh YS
- KMID: 2135365
- J Bacteriol Virol.
- 2014 Mar;44(1):112-114.
- doi: 10.4167/jbv.2014.44.1.112
Cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) is a cytosolic DNA sensor that plays an important role in innate immunity. Transfection of DNA or DNA virus infection results in the... -
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- NLRP6 as a Negative Regulator of Innate Immunity
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Manzoor Z, Koh YS
- KMID: 1782704
- J Bacteriol Virol.
- 2013 Mar;43(1):64-66.
- doi: 10.4167/jbv.2013.43.1.64
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) play important role in immune responses by regulating nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB), type I interferon and inflammasomes. Nod-like receptor... -
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- Mitogen-activated Protein Kinase Signaling in Inflammation-related Carcinogenesis
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Manzoor Z, Koo JE, Koh YS
- KMID: 1737317
- J Bacteriol Virol.
- 2014 Dec;44(4):297-304.
- doi: 10.4167/jbv.2014.44.4.297
The role of mitogen-activated protein kinases (MAPKs) in regulation of inflammation is well known. MAPK family is activated by various stimuli and involved in transmitting extracellular signals to nucleus leading... -
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- PKR as a Regulator of Inflammasome Activation
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Manzoor Z, Koh YS
- KMID: 2168684
- J Bacteriol Virol.
- 2013 Jun;43(2):145-147.
- doi: 10.4167/jbv.2013.43.2.145
Detection of pathogen by pattern recognition receptors leads to activation of inflammasome which plays a crucial role in immune system. The inflammasome regulates the release of cytokines, such as interleukin... -
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- Mitogen-activated Protein Kinases in Inflammation
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Manzoor Z, Koh YS
- KMID: 1434747
- J Bacteriol Virol.
- 2012 Sep;42(3):189-195.
- doi: 10.4167/jbv.2012.42.3.189
Mitogen-activated protein kinases (MAPKs) play critical regulatory roles in the production of the pro-inflammatory cytokines and downstream signaling events which lead to inflammation. Inflammation is a primarily localized and protective... -
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- An Update on Gut Microbiota and Infant's Health
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Manzoor Z, Koh YS
- KMID: 2366877
- J Bacteriol Virol.
- 2016 Dec;46(4):303-306.
- doi: 10.4167/jbv.2016.46.4.303
Childhood malnutrition is a global problem and one of the leading cause of stunted growth, and responsible for the death of millions of children every year. Although extensive efforts have... -
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- 3-Hydroxy-4,7-megastigmadien-9-one, Isolated from Ulva pertusa Kjellman, Inhibits LPS-Induced Inflammatory Response by Down-Regulating Mitogen-Activated Protein Kinase and NF-κB Pathways
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Ali I, Manzoor Z, Koh YS
- KMID: 2353852
- J Bacteriol Virol.
- 2016 Sep;46(3):167-172.
- doi: 10.4167/jbv.2016.46.3.167
In the present study we evaluated the anti-inflammatory potential of 3-hydroxy-4,7-megastigmadien-9-one (Comp) isolated from Ulva pertusa Kjellman, in LPS-stimulated bone marrow-derived dendritic cells (BMDCs). Comp treatment exhibited strong dose dependent... -
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- Anti-inflammatory Effect of Plocamium telfairiae Extract in LPS-stimulated Bone Marrow-derived Macrophages and Dendritic Cells
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Shrestha E, Kim S, Chae D, Manzoor Z, Yoo ES, Kang HK, Hyun JW, Ko MH, Koh YS
- KMID: 2135362
- J Bacteriol Virol.
- 2014 Mar;44(1):95-101.
- doi: 10.4167/jbv.2014.44.1.95
Marine algae are rich sources of various biologically active compounds with potential pharmaceutical properties. In the present study, we investigated the inhibitory effects of Plocamium telfairiae extract (PTE) on proinflammatory... -
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- Acrosorium polyneurum Extract Inhibits the LPS-Induced Inflammatory Response by Impairing the MAPK and NF-κB Pathways
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Manzoor Z, Ali I, Chae D, Koh YS
- KMID: 2366875
- J Bacteriol Virol.
- 2016 Dec;46(4):288-294.
- doi: 10.4167/jbv.2016.46.4.288
Marine algae exhibit broad spectrum anti-bacterial and anti-inflammatory activities. Acrosorium polyneurum (A. polyneurum) is a marine red alga and belongs to the family Delesseriaceae. The present research evaluates the antiinflammatory... -
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