- Protective effects of D-005, a lipid extract from Acrocomia crispa fruits, against ischemia/reperfusion-induced acute kidney injury in rats
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Oyarzábal-Yera A, RodrÃguez-Salgueiro S, Merino-GarcÃa N, Ocaña-Nápoles L, González-Núñez L, Mena-Valdés L, Zamora-RodrÃguez Z, Medina-PÃrez JA, Jiménez-Despaigne S, Molina-Cuevas V
- KMID: 2469376
- Kidney Res Clin Pract.
- 2019 Dec;38(4):462-471.
- doi: 10.23876/j.krcp.19.053
BACKGROUND: Acute kidney injury (AKI) induced by renal ischemia/reperfusion (IR) is associated with enhanced production of reactive oxygen species in renal tissues. D-005, a lipid extract obtained from Acrocomia crispa... -
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- Antioxidant and antiobesity activities of oral treatment with ethanol extract from sprout of evening primrose (Oenothera laciniata) in high fat diet-induced obese mice
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Kwak CS, Kim MJ, Kim SG, Park S, Kim IG, Kang HS
- KMID: 2466667
- J Nutr Health.
- 2019 Dec;52(6):529-539.
- doi: 10.4163/jnh.2019.52.6.529
PURPOSE: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL... -
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- Examination of protective and therapeutic effects of ruscogenin on cerulein-induced experimental acute pancreatitis in rats
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Ercan G, Ä°lbar Tartar R, Solmaz A, Gulcicek O, Karagulle , Meric S, Cayoren H, Kusaslan R, Kemik A, Gokceoglu Kayali D, Cetinel S, Celik A
- KMID: 2464782
- Ann Surg Treat Res.
- 2019 Dec;97(6):271-281.
- doi: 10.4174/astr.2019.97.6.271
PURPOSE: To determine the potential protective and therapeutic effects and action mechanism of ruscogenin on cerulein-induced acute pancreatitis (AP) model in rats. METHODS: Overall, 32 rats were attenuated to the sham... -
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- Effect of lutein on methotrexate-induced oxidative lung damage in rats: a biochemical and histopathological assessment
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Mammadov R, Suleyman B, Akturan S, Cimen FK, Kurt N, Suleyman Z, Malkoc I
- KMID: 2463486
- Korean J Intern Med.
- 2019 Nov;34(6):1279-1286.
- doi: 10.3904/kjim.2018.145
BACKGROUND/AIMS: This study aimed to investigate the effect of lutein on methotrexate (MTX)-induced pulmonary toxicity in rats biochemically and histopathologically. METHODS: The rats in the MTX + lutein (MTXL, n =... -
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- Effects of short-term atorvastatin use in patients with calcium stones: A randomized placebo-controlled clinical trial
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Taheri F, Taheri M, Basiri A, Khoshdel A, Samadian F, Tavasoli S
- KMID: 2461059
- Investig Clin Urol.
- 2019 Nov;60(6):472-479.
- doi: 10.4111/icu.2019.60.6.472
PURPOSE: A few experimental and observational studies have reported that atorvastatin prevents calcium oxalate stone formation. Our study is the first to investigate the effect of atorvastatin on 24-hour urinary... -
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- Comparison of toxic responses to acetaminophen challenge in ICR mice originating from different sources
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Jeong TB, Kim JH, Kim SH, Lee S, Son SW, Lim Y, Cho JY, Hwang DY, Kim KS, Kwak JH, Jung YS
- KMID: 2470006
- Lab Anim Res.
- 2019 Oct;35(3):107-113.
- doi: 10.1186/s42826-019-0017-x
Acetaminophen (APAP) is the most common antipyretic analgesic worldwide. However, APAP overdose causes severe liver injury, especially centrilobular necrosis, in humans and experimental animals. At therapeutic dosage, APAP is mainly... -
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- Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial
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Eshghi F, Bakhshimoghaddam F, Rasmi Y, Alizadeh M
- KMID: 2461099
- Clin Nutr Res.
- 2019 Oct;8(4):318-328.
- doi: 10.7762/cnr.2019.8.4.318
Obesity is a substantial public health challenge across the globe. The use of resistant starch has been proposed as a probable management strategy for complications of obesity. We investigated the... -
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- Effects of Isoflavone Supplementation on Lipid Profiles and Antioxidant Enzyme Activities in Growing Rats Fed High Fat Diet
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Jang IS, Choi MJ
- KMID: 2461097
- Clin Nutr Res.
- 2019 Oct;8(4):296-306.
- doi: 10.7762/cnr.2019.8.4.296
The purpose of this study was to investigate the effects of isoflavone on serum lipids and antioxidant enzymes activities in growing rats fed high lard diet. Twenty four female Sprague-Dawley... -
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- Urine Malondialdehyde and 8-hydroxydeoxyguanosine Levels as Indices of Oxidative Damage in Patients with Atopic Dermatitis
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Choi MW, Kim YS, Lee JH, Han TY
- KMID: 2465953
- Korean J Dermatol.
- 2019 Sep;57(8):457-463.
BACKGROUND: The involvement of oxidative stress in the pathogenesis of various skin diseases has been suggested. OBJECTIVE: Urinary malondialdehyde (MDA) and 8-hydroxydeoxyguanosine (8-OHdG) levels served as indices of oxidative stress. We... -
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- Oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome in a Nigerian tertiary hospital
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Enechukwu , Onuegbu AJ, Olisekodiaka MJ, Eleje GU, Ikechebelu JI, Ugboaja JO, Amah UK, Okwara JE, Igwegbe AO
- KMID: 2456829
- Obstet Gynecol Sci.
- 2019 Sep;62(5):335-343.
- doi: 10.5468/ogs.2019.62.5.335
OBJECTIVE: To determine the activities of oxidative stress markers and lipid profiles of patients with polycystic ovary syndrome (PCOS) in Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria. METHODS: This was a... -
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- Effect of Yeonsan Ogye bioactive peptides on anti-oxidant indexes in rats' liver
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Kim HW, Shim JH, Kim KN
- KMID: 2455855
- J Nutr Health.
- 2019 Aug;52(4):408-411.
- doi: 10.4163/jnh.2019.52.4.408
PURPOSE: This study investigated the effect of bioactive Yeonsan Ogye peptides (YOPs) intake on changes in the hepatic anti-oxidant indexes in male rats. METHODS: Sprague-Dawley male rats were divided into 3... -
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- Protective effect of dietary oils containing omega-3 fatty acids against glucocorticoid-induced osteoporosis
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Elbahnasawy AS, Valeeva ER, El-Sayed E, Stepanova
- KMID: 2455848
- J Nutr Health.
- 2019 Aug;52(4):323-331.
- doi: 10.4163/jnh.2019.52.4.323
PURPOSE: Glucocorticoids (GCs) are implicated in secondary osteoporosis, and the resulting fractures cause significant morbidity. Polyunsaturated fatty acids (PUFAs) play a vital role in bone metabolism. However, few trials have... -
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- 7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
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Ko YH, Kim SK, Kwon SH, Seo JY, Lee BR, Kim YJ, Hur KH, Kim SY, Lee SY, Jang CG
- KMID: 2455091
- Biomol Ther.
- 2019 Jul;27(4):363-372.
- doi: 10.4062/biomolther.2018.211
Daidzein isolated from soybean (Glycine max) has been widely studied for its antioxidant and anti-inflammatory activities. However, the protective effects of 7,8,4′-trihydroxyisoflavone (THIF), a major metabolite of daidzein, on 6-hydroxydopamine... -
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- Hepatoprotective effect of sodium hydrosulfide on hepatic encephalopathy in rats
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Kwon KW, Nam Y, Choi WS, Kim TW, Kim GM, Sohn UD
- KMID: 2450493
- Korean J Physiol Pharmacol.
- 2019 Jul;23(4):263-270.
- doi: 10.4196/kjpp.2019.23.4.263
Hydrogen sulfide is well-known to exhibit anti-inflammatory and cytoprotective activities, and also has protective effects in the liver. This study aimed to examine the protective effect of hydrogen sulfide in... -
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- Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress
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Kim J, Kim J, Huang Z, Goo N, Bae HJ, Jeong Y, Park HJ, Cai M, Cho K, Jung SY, Bae SK, Ryu JH
- KMID: 2447860
- Biomol Ther.
- 2019 May;27(3):327-335.
- doi: 10.4062/biomolther.2019.046
As the elderly population is increasing, Alzheimer's disease (AD) has become a global issue and many clinical trials have been conducted to evaluate treatments for AD. As these clinical trials... -
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- A 1:1 exercise-to-rest period ratio needed by animals to restore energy sources and replenish anti-oxidative status after exercise
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Yeom MY, Cho YO
- KMID: 2434072
- Nutr Res Pract.
- 2019 Feb;13(1):17-22.
- doi: 10.4162/nrp.2019.13.1.17
BACKGROUND/OBJECTIVES: Successful recovery of an animal from exercise is essential, especially prior to the next exercise session. This study was conducted to find an effective exercise-to-rest period ratio for the... -
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- Neuroprotective Effects of Spinosin on Recovery of Learning and Memory in a Mouse Model of Alzheimer's Disease
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Xu F, He B, Xiao F, Yan T, Bi K, Jia Y, Wang Z
- KMID: 2432069
- Biomol Ther.
- 2019 Jan;27(1):71-77.
- doi: 10.4062/biomolther.2018.051
Previous studies have shown that spinosin was implicated in the modulation of sedation and hypnosis, while its effects on learning and memory deficits were rarely reported. The aim of this... -
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- Effects of hyperbaric oxygen and iloprost on intestinal ischemia-reperfusion induced acute lung injury
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Yilmaz Y, Tumkaya L
- KMID: 2429752
- Ann Surg Treat Res.
- 2019 Jan;96(1):34-40.
- doi: 10.4174/astr.2019.96.1.34
PURPOSE: To research the effects of iloprost (IL) and hyperbaric oxygen (HBO) combination treatment on lung injury and on tumor necrosis factor alpha (TNF-α), myeloperoxidase (MPO), malondialdehyde (MDA), and soluble... -
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- Plasma Adropin as a Potential Marker Predicting Obesity and Obesity-associated Cancer in Korean Patients With Type 2 Diabetes Mellitus
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Choi HN, Yim JE
- KMID: 2447451
- J Cancer Prev.
- 2018 Dec;23(4):191-196.
- doi: 10.15430/JCP.2018.23.4.191
BACKGROUND: Type 2 diabetes mellitus (T2DM) and cancer are serious health problems worldwide, and their prevalences have been on the rise in recent years. It has been reported that adropin... -
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- Cytoprotective Effect of Taurine against Hydrogen Peroxide-Induced Oxidative Stress in UMR-106 Cells through the Wnt/β-Catenin Signaling Pathway
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Lou J, Han D, Yu H, Yu G, Jin M, Kim SJ
- KMID: 2427512
- Biomol Ther.
- 2018 Nov;26(6):584-590.
- doi: 10.4062/biomolther.2018.049
Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role in osteoblasts is not clearly understood. The aim of... -
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