- Expression of major histocompatibility complex antigen in Lewis rat cornea
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Tchah H
- KMID: 1735126
- Korean J Ophthalmol.
- 1994 Dec;8(2):66-71.
- doi: 10.3341/kjo.1994.8.2.66
Fresh rat corneas as well as corneas preserved in several different corneal preservation media were stained with Avidin-Biotin-peroxidase Complex method in order to evaluate major histocompatibility complex (MHC) antigen expression.... -
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- Priming of Autoreactive CD8+ T Cells Is Inhibited by Immunogenic Peptides Which Are Competitive for Major Histocompatibility Complex Class I Binding
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You S, Choi YS, Hong S, Shin EC
- KMID: 2150771
- Immune Netw.
- 2013 Jun;13(3):86-93.
- doi: 10.4110/in.2013.13.3.86
In the present study, we investigated if priming of autoreactive CD8+ T cells would be inhibited by competitive peptides for major histocompatibility complex (MHC) class I binding. We used a... -
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- Species specificity of a novel factor which augments the expression of MHC class I antigens on tumor cell lines
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Puri N, Raval A, Saxena RK
- KMID: 2045609
- Exp Mol Med.
- 1997 Jun;29(2):129-132.
A novel factor which augments the expression of major histocompatibility complex I (MHC augmenting factor or MHC-AF) antigens on tumor cell lines, has been isolated from the culture supernatants of... -
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- The degree of major histocompatibility complex matching between purebred Maltese and mongrel dogs using microsatellite markers
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Kwak HH, Woo HM, Park KM
- KMID: 2454008
- J Vet Sci.
- 2019 Mar;20(2):e5.
- doi: 10.4142/jvs.2019.20.e5
Long-term maintenance of transplanted organs is one of the major factors that increases survival time of recipients. Although obtaining a major histocompatibility complex (MHC)-matched donor with the recipient is essential... -
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- MergeReference: A Tool for Merging Reference Panels for HLA Imputation
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Cook S, Han B
- KMID: 2394767
- Genomics Inform.
- 2017 Sep;15(3):108-111.
- doi: 10.5808/GI.2017.15.3.108
Recently developed computational methods allow the imputation of human leukocyte antigen (HLA) genes using intergenic single nucleotide polymorphism markers. To improve the imputation accuracy in HLA imputation, it is essential... -
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- The Role of B Cells in Transplantation Rejection
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Kim TJ
- KMID: 2408661
- J Korean Soc Transplant.
- 2018 Mar;32(1):1-6.
- doi: 10.4285/jkstn.2018.32.1.1
B cells play a role in graft rejection via several mechanisms. Specifically, B cells produce high-affinity antibodies to alloantigens including allogeneic major histocompatibility complex (MHC) with the help of follicular... -
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- Human Embryonic Stem Cell Derived from Early Stage Fertilized Ovum: Non Immunogenic and Universal, Neuronal and Non-neuronal Cell Lines
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Shroff G, Srivastav , Shroff R
- KMID: 2413506
- Int J Stem Cells.
- 2018 Jun;11(1):105-110.
- doi: 10.15283/ijsc17064
BACKGROUND: Human embryonic stem cells (hESCs) have the potential to treat various human disorders currently labeled as incurable and/or terminal illness. However, the fear that the patients' immune system would... -
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- Significance of HLA Type and Frequency of Korean HLA
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Chae JR, Jung JO, Shin DH
- KMID: 1667854
- J Korean Pediatr Soc.
- 1980 Feb;23(2):89-97.
Through the recent study, we have come to know that the gene group, which has an important function, is closely existed in the part of 6 chromosome short arm of... -
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- T Cell's Sense of Self: a Role of Self-Recognition in Shaping Functional Competence of Naïve T Cells
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Kim HO, Cho JH
- KMID: 2388075
- Immune Netw.
- 2017 Aug;17(4):201-213.
- doi: 10.4110/in.2017.17.4.201
Post-thymic naïve T cells constitute a key cellular arm of adaptive immunity, with a well-known characteristic of the specificity and robustness of responses to cognate foreign antigens which is presented... -
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- Extracellular vesicles in renal physiology and clinical applications for renal disease
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Kwon SH
- KMID: 2448338
- Korean J Intern Med.
- 2019 May;34(3):470-479.
- doi: 10.3904/kjim.2019.108
Many cells in the nephron release extracellular vesicles (EVs). EVs envelop nucleic acids, proteins, and lipids. The surfaces of EVs express donor cell-specific markers, ligands, and major histocompatibility complex molecules.... -
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- Inhibition of Major Histocompatibility Complex (MHC)- Restricted Presentation of Exogenous Antigen in Dendritic Cells by Korean Propolis Components
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Han S, Cho K, Lee S, Lee CK, Song Y, Ha N, Kim K
- KMID: 2150610
- Immune Netw.
- 2005 Sep;5(3):150-156.
- doi: 10.4110/in.2005.5.3.150
BACKGROUND: Dendritic cells (DCs) play a critical role not only in the initiation of immune responses, but also in the induction of immune tolerance. In an effort to regulate immune... -
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- Sepsis Mortality in CIITA Deficient Mice is Associated with Excessive Release of High-mobility Group Box 1
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Kim JY, Kim JH, Seo JN, Oh KI
- KMID: 1484312
- Immune Netw.
- 2008 Jun;8(2):39-45.
- doi: 10.4110/in.2008.8.2.39
BACKGROUND: Down regulation of major histocompatibility complex class II transactivator (CIITA) has been identified as a major factor of immunosuppression in sepsis and the level of CIITA expression inversely correlates... -
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- Serum beta-2 microglobulin in malignant lymphomas: an old but powerful prognostic factor
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Yoo C, Yoon DH, Suh C
- KMID: 2172785
- Blood Res.
- 2014 Sep;49(3):148-153.
- doi: 10.5045/br.2014.49.3.148
Beta-2 microglobulin is synthesized in all nucleated cells and forms the light chain subunit of the major histocompatibility complex class I antigen. Despite its potential role as a convenient and... -
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- The Emerging Role of Natural Killer Cells in Innate and Adaptive Immunity
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Kim EM, Ko CB, Myung PK, Cho D, Choi I, Kang HS
- KMID: 1515487
- Immune Netw.
- 2004 Dec;4(4):205-215.
- doi: 10.4110/in.2004.4.4.205
In the early host defense system, effector function of natural killer (NK) cells results in natural killing against target cells such as microbe-infected, malignant, and certain allogenic cells without prior... -
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- HLA and Disease Associations in Koreans
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Ahn S, Choi HB, Kim TG
- KMID: 2150716
- Immune Netw.
- 2011 Dec;11(6):324-335.
- doi: 10.4110/in.2011.11.6.324
The human leukocyte antigen (HLA), the major histocompatibility complex (MHC) in humans has been known to reside on chromosome 6 and encodes cell-surface antigen-presenting proteins and many other proteins related... -
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- A Cabe of Clozapine-Induced Agranulocytosis
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Lee GC, Jung HK, Lee JH, Choi YM, Jeon SI, Choi SJ
- KMID: 2017707
- J Korean Neuropsychiatr Assoc.
- 1998 Jan;37(1):186-193.
We report a 20-year-old female patient who developed clozapine-induced agranulocytosis on the 29th day of clozapine treatment. She recovered from the agranulocytosis on the 8th day of progression after treatment... -
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- Genetic variability of six indigenous goat breeds using major histocompatibility complex-associated microsatellite markers
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Salles P, Santos SC, Rondina D, Weller M
- KMID: 1106554
- J Vet Sci.
- 2011 Jun;12(2):127-132.
- doi: 10.4142/jvs.2011.12.2.127
The present study aimed at analyzing the genetic variability of indigenous goat breeds (Capra hircus) using the MHC-associated microsatellite markers BF1, BM1818, BM1258, DYMS1, and SMHCC1. The following breeds were... -
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- Hair Cycle-associated Changes of the Immunological Markers in Human Hair Follicles
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Won CH, Oh JK, Lee MK, Lee SR, Li K, Choi CW, Kim KH, Cho KH, Eun HC
- KMID: 2302345
- Korean J Dermatol.
- 2006 Jan;44(1):1-7.
BACKGROUND: The immunological characteristics of human hair follicles with the hair growth cycle have not yet been fully elucidated. It is suggested that expressional changes of the immunological markers in... -
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- Osteoclasts: Crucial in Rheumatoid Arthritis
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Jeong WJ, Kim HJ
- KMID: 2326728
- J Rheum Dis.
- 2016 Jun;23(3):141-147.
- doi: 10.4078/jrd.2016.23.3.141
Osteoclasts are a major component of bone metabolism in physiologic condition and in rheumatoid arthritis (RA). RA is a chronic, autoimmune, inflammatory disease primarily affecting the joints. Joint inflammation leads... -
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- Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications
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Yoo S, Ha SJ
- KMID: 2154811
- Immune Netw.
- 2016 Feb;16(1):52-60.
- doi: 10.4110/in.2016.16.1.52
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that bridge innate and adaptive immune responses, thereby leading to immune activation. DCs have been known to recognize pathogen-associated molecular patterns such... -
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