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Heavy metal concentrations in hair of newly imported China-origin rhesus macaques (Macaca mulatta)

Lee JI, Jung WY, Lee G, Kim MS, Kim YS, Park CG, Kim SJ

Macaque monkeys are good sentinel to humans for environmental pollutions because their similarities in genetic and physiological characteristics. So, their reference values about exposures to heavy metals are required for...
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Shigella flexneri infection in a newly acquired rhesus macaque (Macaca mulatta)

Lee JI, Kim SJ, Park CG

A 3.4 year-old rhesus macaque weighing 4.5 kg, was suffering from anorexia, acute mucous and bloody diarrhea. On physical examination, the monkey showed a loss of activity, hunched posture, abdominal...
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Studies of G Protein Activation of Orphanin FQ in the Cerebrum, Thalamus and Spinal Cord of Monkeys

Lee H, Han JI

BACKGROUND: The aim of this in vitro study was to investigate [35S]GTP gamma S binding stimulated activation by orphanin FQ in monkey cerebral, thalamic, and spinal membranes. METHODS: A rhesus monkey...
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Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR

Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and...
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A Case of Posterior Ciliary Artary Occlusion

Jung GY, Lee JH, Park SH, Shin H

  • KMID: 1949403
  • J Korean Ophthalmol Soc.
  • 1988 Aug;29(4):763-767.
The clinical picture of central retinal artery occlusion is well known. Little is known, however, about the clinical picture of occlusion of the posterior cilliary arteries. The effects of such...
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Dynorphin A (1-17) was Selective tomicro-Opioid Receptor in Agonist-Stimulated [35S] GTPgammaS Binding in Cortical and Thalamic Membranes of Monkey

Lee H, Lee SA, Kang SY, Kim DY, Kim CH

BACKGROUND: Dynorphin A (1-17) is conceived as an endogenous opioid peptide with a high degree of selectivity forkappa- opioid receptor even though it has been reported to sometimes act like...
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A Histologic Demonstration of Siliceous Materials in Simian Lung Mite Infected Lung Tissues by Microincineration

Kim JC, Kim MK

  • KMID: 1089400
  • J Vet Sci.
  • 2003 Aug;4(2):117-123.
Approximately 90% of freshly imported macaques and other Old World Monkeys are known to be infected with respiratory mites. The lung associated pigments are integral components of pulmonary acariasis in...
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Cardiopulmonary effects of thiopental versus propofol as an induction agent prior to isoflurane anesthesia in chair trained rhesus macaques (Macaca mulatta)

Choi YJ, Park HJ, Kim HH, Lee YJ, Jung KC, Park SH, Lee JI

The purpose of this study was to evaluate the effects of thiopental versus propofol on cardiopulmonary functions, when used as an induction agent prior to isoflurane anesthesia in rhesus monkeys....
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Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys

Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR

The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in...
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Suppurative bite wound by repetitive aggression of dominance hierarchy during group housing in rhesus monkeys

Choi Y, Ahn KH, Lee JI

Group formation of rhesus monkeys, often leads to victims of repeated attacks by the high ranking animal. We reported a case of an injured middle ranking monkey from repetitive and...
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Effect of a modified rectus tuck on anterior ciliary artery perfusion

Park C, Min BM, Wright KW

Strabismus surgery results in the permanent interruption of anterior ciliary blood flow, predisposing the eye to anterior segment ischemia (ASI). A primate model was used to assess the effectiveness of...
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The Clinical Investigation of Gastric Volume and pH Under General Anesthesia

Chung YT, Kim MY, Kim YS, Park DH, Kim WS

  • KMID: 2357524
  • Korean J Anesthesiol.
  • 1979 Dec;12(4):445-451.
In recent years, there has been renewed interest in preoperative methods to reduce gastric acidity, thus lessening the risk of a serious pulmonary reactions following aspiration of gastric contents. Emergency...
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Induction of Rhesus Keratinocytes into Functional Ameloblasts by Mouse Embryonic Dental Mesenchyme

Ruan N, Lin C, Dong X, Hu X, Zhang Y

Fast progresses in stem cell-based tooth tissue engineering have been achieved in recent years in several animal models including the mouse, rat, dog, and pig. Moreover, various postnatal mesenchymal stem...
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Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding

Yamada S, Kuraoka S, Osano A, Ito Y

  • KMID: 2232961
  • Int Neurourol J.
  • 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin...
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Gender-Related Differences in a Process of the Age-Dependent Alterations of the Elements in Monkey Sino-Atrial Node

Satoh H, Tohno S, Minami T, Oishi T, Hayashi M, Tohno Y

Gender differences in the trace elements of monkey sino-atrial (SA) node were investigated in a process of age-dependent alterations. Sixty hearts from Japanese and rhesus monkeys (30 male and 30...
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Application of the Multiplex Cytokine Analysis to Monitor Xenogeneic Immune Responses to the Porcine Islet Graft in Non-Human Primate

Kim YH, Kim JS, Yoon IH, Shin JS, Kim JM, Kim SJ, Park CG

Non-human primate studies must be conducted prior to the clinical trial of xenotransplantation. In order to develop clinically applicable immune-modulatory regimen through non-human primate studies, close monitoring of xenogeneic immune...
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Rise of the Visible Monkey: Sectioned Images of Rhesus Monkey

Chung BS, Jeon CY, Huh JW, Jeong KJ, Har D, Kwack KS, Park JS

BACKGROUND: Gross anatomy and sectional anatomy of a monkey should be known by students and researchers of veterinary medicine and medical research. However, materials to learn the anatomy of a...
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Acute gastrointestinal dilation in laboratory rhesus monkeys in the Korea National Primate Research Center

Kim KM, Lee SR, Chang KS, Lee YH, Kim SW, Jung KJ, Lee Y, Kim D, Chang KT

Acute gastrointestinal dilation is a medical condition in which the stomach and intestine become overstretched by excessive gas content. In laboratory monkeys, cases of bloating involving gastrointestinal dilation are rarely...
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Increase in Anti-Gal IgM Level is Associated With Early Graft Failure in Intraportal Porcine Islet Xenotransplantation

Kang HJ, Lee H, Park EM, Kim JM, Shin JS, Kim JS, Park CG, Kim SJ

BACKGROUND: Anti-Gal is a major antibody induced in non-human primates (NHPs) after xenotransplantation. To understand the mechanism of graft rejection, we investigated the association between anti-Gal responses and graft failure...
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Jennerian reassortment rotavirus vaccines

Kim KH

RQtavirus(Rv) is the most common cause of severe dehydratine diarrhea in infants and young children worldwide, infecting nearly every child in the first few years of life, and thus justif}-ing...
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