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Comparative Studies on the Polyarnine Involvement in MCF - 7 and MDA - MB - 231 Breast Cancer Cell Proliferation

Kim JH, Kim BG

  • KMID: 2175125
  • J Korean Cancer Assoc.
  • 1999 Dec;31(6):1151-1158.
No abstract available.
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Alfa - difluoromethylornithine Reduced Protein Phosphorylation in MCF-7 Human Breast Cancer Cells

Lee JY, Kim BK

  • KMID: 2059303
  • J Korean Cancer Assoc.
  • 1999 Oct;31(5):1044-1053.
No abstract available.
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Inductoin of Radioresistance by Overexpression of Glutathione S-Transferase K1 (hGSTK1) in MCF-7 Cells

Kim JC, Shin SO

  • KMID: 1613505
  • J Korean Soc Ther Radiol Oncol.
  • 2001 Dec;19(4):381-388.
PURPOSE: This study was conducted to assess the effects of x-irradiation on the expression of the novel glutathione S-transferase K1 gene. MATERIALS AND METHODS: Human glutathione S-transferase K1 (hGSTK1) DNA...
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Apoptotic Effects of 6-Gingerol in Human Breast Cancer Cells

Kim HW, Oh DH, Koh JT, Lim YC

6-Gingerol exerts anti-tumor effects in various cancer cell models. We evaluated the effect of 6-gingerol on the growth of MCF-7 breast cancer cells and MCF-10A breast epithelial cells to determine...
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Silibinin Enhances Ultraviolet B-Induced Apoptosis in MCF-7 Human Breast Cancer Cells

Noh EM, Yi MS, Youn HJ, Lee BK, Lee YR, Han JH, Yu HN, Kim JS, Jung SH

PURPOSE: Chemotherapies for breast cancer generally have strong cellular cytotoxicity and severe side effects. Thus, significant emphasis has been placed on combinations of naturally occurring chemopreventive agents. Silibinin is a...
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Mechanical Alteration Associated With Chemotherapeutic Resistance of Breast Cancer Cells

Park S

BACKGROUND: The mechanical deformability of cancer cells has attracted particular attention as an emerging biomarker for the prediction of anti-cancer drug sensitivity. Nevertheless, it has not been possible to establish...
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The Changes of Cell Cycle Phase Fractions and Expression of p53 by the Treatment of Staurosporine in MCF-7 Cell Line

Nam J, Yea KA, Lee HN, Jo HH, Ryu KS, Lew YO, Rha JG, Han KT

  • KMID: 2076195
  • Korean J Obstet Gynecol.
  • 2001 Mar;44(3):501-505.
OBJECTIVE: We investigated the effects on the cell cycle and p53 expression by the treatment of various concentrations of staurosporine to elucidate the molecular mechanism of staurosporine induced cell cycle...
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Effects of retinoic acid isomers on apoptosis and enzymatic antioxidant system in human breast cancer cells

Hong TK, Lee-Kim YC

  • KMID: 2313380
  • Nutr Res Pract.
  • 2009 Jun;3(2):77-83.
Retinoic acids (RAs) modulate growth, differentiation, and apoptosis in normal, pre-malignant & malignant cells. In the present study, the effects of RA isomers (all-trans RA, 13-cis RA, and 9-cis RA)...
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Cytotoxic Lactones from the Pericarps of Litsea japonica

Ngo QM, Cao TQ, Woo MH, Min BS

From the pericarps of Litsea japonica (Thunb.) Jussieu, eighteen butanolide derivatives (1 – 18) were evaluated for their cytotoxic activity against HeLa, HL-60, and MCF-7 cells. Compounds 1 – 9...
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Effects of Polyamines on TNFalpha- or Tamoxifen-induced Apoptosis in Human Breast Cancer Cells

Kim JY, Kim KY, Lee KH, Hong KW, Kim BG

  • KMID: 1804428
  • Cancer Res Treat.
  • 2001 Oct;33(5):385-391.
PURPOSE: To investigate the effects of polyamines on tumor necrosis factor alpha (TNFalpha)-or tamoxifen (TAM)-induced apoptosis in estrogen receptor (ER)-positive MCF- 7 and ER-negative MDA-MB-231 human breast cancer cells. MATERIALS AND...
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Isocryptotanshinone Induced Apoptosis and Activated MAPK Signaling in Human Breast Cancer MCF-7 Cells

Zhang X, Luo W, Zhao W, Lu J, Chen X

PURPOSE: Isocryptotanshinone (ICTS) is a natural bioactive product that is isolated from the roots of the widely used medical herb Salvia miltiorrhiza. However, few reports exist on the mechanisms underlying...
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Regulatory Role of Autophagy in Globular Adiponectin-Induced Apoptosis in Cancer Cells

Nepal S, Park PH

Adiponectin, an adipokine predominantly secreted from adipose tissue, exhibits diverse biological responses, including metabolism of glucose and lipid, and apoptosis in cancer cells. Recently, adiponectin has been shown to modulate...
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Ellagic Acid Shows Different Anti-proliferative Effects Between the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines

Kim HA, Lee RA, Moon BI, Choe KJ

PURPOSE: It has been demonstrated ellagic acid can inhibit tumor growth. However, the mechanism that elicits the anti-proliferative effect of ellagic acid is poorly understood. Our objective in this study...
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Anti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast Cancer

Min KN, Joung KE, Kim DK, Sheen YY

  • KMID: 2380177
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012010.
OBJECTIVES: In recent years, a number of structurally diverse Histone deacetylase (HDAC) inhibitors have been identified and these HDAC inhibitors induce growth arrest, differentiation and/or apoptosis of cancer cells in...
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A Novel Chenodeoxycholic Derivative HS-1200 Enhances Radiation-induced Apoptosis in Human MCF-7 Breast Cancer Cells

Lee HS, Choi YM, Kwon HC, Song YS

  • KMID: 2323832
  • J Korean Soc Ther Radiol Oncol.
  • 2004 Jun;22(2):145-154.
PURPOSE: To examine whether a synthetic bile acid derivatives (HS-1200) sensitizes the radiation-induced apoptosis in human breast cancer cells (MCF-7) and to investigate the underlying mechanism. MATERIALS AND MEHTODS: Human...
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Cell-in-Cell Death Is Not Restricted by Caspase-3 Deficiency in MCF-7 Cells

Wang S, He M, Li L, Liang Z, Zou Z, Tao A

PURPOSE: Cell-in-cell structures are created by one living cell entering another homotypic or heterotypic living cell, which usually leads to the death of the internalized cell, specifically through caspase-dependent cell...
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Effect of bFGF on the MCF-7 Cell Cycle with CD44+/CD24-: Promoting the G0/G1-->G2/S Transition

Yang ZL, Cheng K, Han ZD

PURPOSE: Few cells with stem cell characteristics possess capabilities of self-renewal and differentiation, which leads to high tumorigenesis and resistance to standard chemotherapeutic agents. These cells are mostly quiescent, and...
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CD98 Activation Increases the Invasion of Human Breast Carcinoma MCF-7 Cells

Kim SM, Kim JM, Jeon JS, Ahn ZS, Kim DY, Suh JS, Park KH, Park JH, Kim DJ, Hahn JH

  • KMID: 2283413
  • Korean J Phys Anthropol.
  • 2007 Sep;20(3):225-233.
CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates the func-tions of beta1 integrin, suggesting that it may play a role in tumor cell invasion. In this study, the...
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Protective Effect of PKC Affecting Taxol-induced Cytotoxicity in MCF-7 Cells

Oh JM, Jung KM, Bang HJ, So HS, Park RK, Kim JJ, Choi MK, Park ST, Chung YT

  • KMID: 2224545
  • Korean J Anat.
  • 2000 Oct;33(5):571-578.
Paclitaxel (taxol) is known as effective drug inhibition of cell cycle encouraging activity in human ovarian and metastatic breast cancers and malignant melanoma. It is an antimicrotubule agent that is...
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In Vitro Study of Tumor Seeking Radiopharmaceutical Uptake by Human Breast Cancer Cell Line MCF-7 after Paclitaxel Treatment

Choi JY, Choi Y, Choe YS, Lee KH, Kim BT

  • KMID: 1512506
  • Nucl Med Mol Imaging.
  • 2007 Oct;41(5):364-372.
PURPOSE: This study was designed to investigate the cellular uptake of various tumor imaging radiopharmaceuticals in human breast cancer cells before and after paclitaxel exposure considering viable cell number. MATERIALS AND...
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