- Cyclophosphamide dose: how much is needed to win the war against paraquat poisoning?
-
Sun IO, Lee KY
- KMID: 1503777
- Korean J Intern Med.
- 2013 Jul;28(4):410-412.
- doi: 10.3904/kjim.2013.28.4.410
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Emerging strategies for the treatment of pulmonary tuberculosis: promise and limitations?
-
Yew WW, Koh WJ
- KMID: 2373768
- Korean J Intern Med.
- 2016 Jan;31(1):15-29.
- doi: 10.3904/kjim.2016.31.1.15
A worsening scenario of drug-resistant tuberculosis has increased the need for new treatment strategies to tackle this worldwide emergency. There is a pressing need to simplify and shorten the current... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of sevoflurane on tight junction protein expression and PKC-alpha translocation after pulmonary ischemia-reperfusion injury
-
Chai J, Long B, Liu X, Li Y, Han N, Zhao P, Chen W
- KMID: 2155421
- Exp Mol Med.
- 2015 Jun;47(6):e167.
- doi: 10.1038/emm.2015.27
Pulmonary dysfunction caused by ischemia-reperfusion injury is the leading cause of mortality in lung transplantation. We aimed to investigate the effects of sevoflurane pretreatment on lung permeability, tight junction protein... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Outcome of Paraquat Poisoning
-
Yoon SC
- KMID: 1717957
- Korean J Intern Med.
- 2009 Jun;24(2):93-94.
- doi: 10.3904/kjim.2009.24.2.93
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Steroid Response in Refractory Asthmatics
-
Jang AS
- KMID: 1776538
- Korean J Intern Med.
- 2012 Jun;27(2):143-148.
- doi: 10.3904/kjim.2012.27.2.143
Inhaled glucocorticosteroids are currently the most effective anti-inflammatory controller medications for treating persistent asthma. The efficacies of glucocorticoids include reducing asthma symptoms, reducing exacerbation frequency, improving quality of life, improving... -
- CITED
-
- Close
- SHARE
-
- Close
- Preparation and evaluation of enrofloxacin microspheres and tissue distribution in rats
-
Yang F, Kang J, Yang F, Zhao Z, Kong T, Zeng Z
- KMID: 2164524
- J Vet Sci.
- 2015 Jun;16(2):157-164.
- doi: 10.4142/jvs.2015.16.2.157
New enrofloxacin microspheres were formulated, and their physical properties, lung-targeting ability, and tissue distribution in rats were examined. The microspheres had a regular and round shape. The mean diameter was... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Personal Exposure to Nitrogen Dioxide on Peak Expiratory Flow in Asthmatic Patients
-
Kwon HJ, Lee SG, Jee YK, Lee SR, Hwang SS
- KMID: 792459
- J Prev Med Public Health.
- 2007 Jan;40(1):59-63.
- doi: 10.3961/jpmph.2007.40.1.59
OBJECTIVES: Nitrogen dioxide (NO2) has been inconsistently associated with gradual decreases in lung function. Here, we studied the effects of NO2 exposure in asthmatics by examining the association between... -
- CITED
-
- Close
- SHARE
-
- Close
- The dose of cyclophosphamide for treating paraquat-induced rat lung injury
-
Choi JS, Jou SS, Oh MH, Kim YH, Park MJ, Gil HW, Song HY, Hong SY
- KMID: 1503779
- Korean J Intern Med.
- 2013 Jul;28(4):420-427.
- doi: 10.3904/kjim.2013.28.4.420
BACKGROUND/AIMS: Cyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. METHODS: Adult male Sprague-Dawley rats... -
- CITED
-
- Close
- SHARE
-
- Close
- Attenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?
-
Liu JN, Suh DH, Yang EM, Lee SI, Park HS, Shin YS
- KMID: 2155378
- Exp Mol Med.
- 2014 Sep;46(9):e113.
- doi: 10.1038/emm.2014.55
Although some studies have explained the immunomodulatory effects of statins, the exact mechanisms and the therapeutic significance of these molecules remain to be elucidated. This study not only evaluated the... -
- CITED
-
- Close
- SHARE
-
- Close
- Exposure to Cerium Oxide Nanoparticles Is Associated With Activation of Mitogen-activated Protein Kinases Signaling and Apoptosis in Rat Lungs
-
Rice KM, Nalabotu S, Manne ND, Kolli MB, Nandyala G, Arvapalli , Ma JY, Blough ER
- KMID: 2381462
- J Prev Med Public Health.
- 2015 May;48(3):132-141.
- doi: 10.3961/jpmph.15.006
OBJECTIVES: With recent advances in nanoparticle manufacturing and applications, potential exposure to nanoparticles in various settings is becoming increasing likely. No investigation has yet been performed to assess whether respiratory... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of administration of IH901, a ginsenoside intestinal metabolite, on muscular and pulmonary antioxidant functions after eccentric exercise
-
Lee NJ, Lee JW, Sung JH, Ko YG, Hwang S, Kang JK
- KMID: 1705554
- J Vet Sci.
- 2013 Sep;14(3):249-256.
- doi: 10.4142/jvs.2013.14.3.249
This study was conducted to investigate whether administration of IH901, a ginseng intestinal metabolite, ameliorates exercise-induced oxidative stress while preserving antioxidant defense capability in rat skeletal muscles and lung. Eight... -
- CITED
-
- Close
- SHARE
-
- Close
- Erythropoietin Attenuates Hyperoxia-Induced Lung Injury by Down-modulating Inflammation in Neonatal Rats
-
Lee JH, Sung DK, Koo SH, Shin BK, Hong YS, Son CS, Lee JW, Chang YS, Park WS
- KMID: 1785767
- J Korean Med Sci.
- 2007 Dec;22(6):1042-1047.
- doi: 10.3346/jkms.2007.22.6.1042
This study was done to determine whether recombinant human erythropoietin (rhEPO) treatment could attenuate hyperoxia-induced lung injury, and if so, whether this protective effect is mediated by the down-modulation of... -
- CITED
-
- Close
- SHARE
-
- Close
- Granulocyte Colony Stimulating Factor Attenuates Hyperoxia-Induced Lung Injury by Down-Modulating Inflammatory Responses in Neonatal Rats
-
Jeon GW, Sung DK, Jung YJ, Koo SH, Choi SH, Chang YS, Sin JB, Park WS
- KMID: 1106439
- Yonsei Med J.
- 2011 Jan;52(1):65-73.
- doi: 10.3349/ymj.2011.52.1.65
PURPOSE: Granulocyte colony stimulating factor (G-CSF) has been known to increase neutrophil production and have anti-inflammatory properties, but the effect of G-CSF on pulmonary system is in controversy. We investigated... -
- CITED
-
- Close
- SHARE
-
- Close
- Marked Recovery From Paraquat-Induced Lung Injury During Long-Term Follow-up
-
Lee KH, GIL HW, Kim YT, Yang JO, Lee EY, Hong SY
- KMID: 1717958
- Korean J Intern Med.
- 2009 Jun;24(2):95-100.
- doi: 10.3904/kjim.2009.24.2.95
BACKGROUND/AIMS: Paraquat-induced lung injury has been considered a progressive and irreversible disease. The purpose of this study was to report the long-term evolution of lung lesions in eight survivors with... -
- CITED
-
- Close
- SHARE
-
- Close
- Nanoparticles-A Thoracic Toxicology Perspective
-
Duffin R, Mills NL, Donaldson
- KMID: 2158160
- Yonsei Med J.
- 2007 Aug;48(4):561-572.
- doi: 10.3349/ymj.2007.48.4.561
A substantial literature demonstrates that the main ultrafine particles found in ambient urban air are combustion-derived nanoparticles (CDNP) which originate from a number of sources and pose a hazard to... -
- CITED
-
- Close
- SHARE
-
- Close
- miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy
-
Wang F, Lou JF, Cao Y, Shi XH, Wang P, Xu J, Xie EF, Xu T, Sun RH, Rao JY, Huang PW, Pan SY, Wang H
- KMID: 2155654
- Exp Mol Med.
- 2015 May;47(5):e162.
- doi: 10.1038/emm.2015.17
MicroRNAs (miRNAs), a class of small non-coding RNAs, mediate gene expression by either cleaving target mRNAs or inhibiting their translation. They have key roles in the tumorigenesis of several cancers,... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of pycnogenol on antioxidant enzymes in a mouse model of ozone exposure
-
Lee MS, Moon KY, Bae DJ, Park MK, Jang AS
- KMID: 1501777
- Korean J Intern Med.
- 2013 Mar;28(2):216-223.
- doi: 10.3904/kjim.2013.28.2.216
BACKGROUND/AIMS: Ozone is an environmentally reactive oxidant, and pycnogenol is a mixture of flavonoid compounds extracted from pine tree bark that have antioxidant activity. We investigated the effects of pycnogenol... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Particulate Matter (PM10) on The Pulmonary Function of Middle-School Children
-
Kim JH, Lim DH, Kim JK, Jeong SJ, Son BK
- KMID: 1781722
- J Korean Med Sci.
- 2005 Feb;20(1):42-45.
- doi: 10.3346/jkms.2005.20.1.42
It has been reported that the particulate matter under 10 micrometer (PM10) has deleterious effects on respiratory health. The purpose of this study was to assess the influence of PM10... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma
-
Lee HY, Rhee CK, Kang JY, Park CK, Lee SY, Kwon SS, Kim YK, Yoon HK
- KMID: 2373777
- Korean J Intern Med.
- 2016 Jan;31(1):89-97.
- doi: 10.3904/kjim.2016.31.1.89
BACKGROUND/AIMS: Asthma is characterized by airway hyperresponsiveness, inflammation, and remodeling. Peroxisome proliferator-activated receptors have been reported to regulate inflammatory responses in many cells. In this study, we examined the effects... -
- CITED
-
- Close
- SHARE
-
- Close
- Relationship between Pulmonary Surfactant Protein and Lipid Peroxidation in Lung Injury due to Paraquat Intoxication in Rats
-
Gil HW, Oh MH, Woo KM, Lee EY, Oh MH, Hong SY
- KMID: 1091864
- Korean J Intern Med.
- 2007 Jun;22(2):67-72.
- doi: 10.3904/kjim.2007.22.2.67
BACKGROUND: Pulmonary damage resulting from lipid peroxidation is a principal effect of paraquat intoxication. The host-defense functions of surfactant are known to be mediated by the surfactant proteins A... -
- CITED
-
- Close
- SHARE
-
- Close
