- MicroRNA-138 Suppresses Adipogenic Differentiation in Human Adipose Tissue-Derived Mesenchymal Stem Cells by Targeting Lipoprotein Lipase
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Wang Y, Lin L, Huang Y, Sun J, Wang X, Wang P
- KMID: 2463798
- Yonsei Med J.
- 2019 Dec;60(12):1187-1194.
- doi: 10.3349/ymj.2019.60.12.1187
PURPOSE: Adipogenic differentiation of adipose tissue-derived mesenchymal stem cells (AMSCs) is critical to many disease-related disorders, such as obesity and diabetes. Studies have demonstrated that miRNA-138 (miR-138) is closely involved... -
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- Fumigaclavine C attenuates adipogenesis in 3T3-L1 adipocytes and ameliorates lipid accumulation in high-fat diet-induced obese mice
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Yu WG, He Y, Chen YF, Gao XY, Ning WE, Liu CY, Tang TF, Liu Q, Huang XC
- KMID: 2443604
- Korean J Physiol Pharmacol.
- 2019 May;23(3):161-169.
- doi: 10.4196/kjpp.2019.23.3.161
Fumigaclavine C (FC), an active indole alkaloid, is obtained from endophytic Aspergillus terreus (strain No. FC118) by the root of Rhizophora stylosa (Rhizophoraceae). This study is designed to evaluate whether... -
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- Blood Sugar Control and Low-Carbohydrate High-Fat Diet
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Kang EH
- KMID: 2442363
- J Korean Diabetes.
- 2018 Dec;19(4):237-245.
- doi: 10.4093/jkd.2018.19.4.237
Diabetes patients and pre-diabetic patients are increasing worldwide. Type 2 diabetes starts with insulin resistance, and the long-term habit of stimulating insulin secretions causes insulin resistance and accumulates body fat... -
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- Triglyceride-Rich Lipoproteins and Novel Targets for Anti-atherosclerotic Therapy
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Reiner Z
- KMID: 2424560
- Korean Circ J.
- 2018 Dec;48(12):1097-1119.
- doi: 10.4070/kcj.2018.0343
Although elevated serum low-density lipoprotein-cholesterol (LDL-C) is without any doubts accepted as an important risk factor for cardiovascular disease (CVD), the role of elevated triglycerides (TGs)-rich lipoproteins as an independent... -
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- Platycodi radix beverage ameliorates postprandial lipemia response through lipid clearance of triglyceride-rich lipoprotein: A randomized controlled study in healthy subjects with a high-fat load
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Lee H, Lim Y, Park SY, Cho SM, Choe JS, Jeong S, Kwak JS, Kwon O
- KMID: 2446996
- Nutr Res Pract.
- 2018 Oct;12(5):371-377.
- doi: 10.4162/nrp.2018.12.5.371
BACKGROUND/OBJECTIVES: Elevation of postprandial lipemia characterized by a rise in triglyceride (TG)-rich lipoproteins can increase the risk of atherogenesis. The objective of this study was to investigate postprandial lipemia response... -
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- LPL gene Pvu II polymorphism and hypertriglyceridemia: a meta-analysis involving 1,640 subjects
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Li YY, Zhou YH, Gong G, Geng HY, Yang XX, Wang XM, Zhou CW, Xu J, Qian Y
- KMID: 2396761
- Korean J Intern Med.
- 2017 Nov;32(6):1018-1024.
- doi: 10.3904/kjim.2016.043
BACKGROUND/AIMS: Although lipoprotein lipase (LPL) gene Pvu II polymorphism has been associated with an increased risk of hypertriglyceridemia (HT), there is no clear consensus within the scientific community. METHODS: A meta-analysis... -
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- Homozygous LPL p.Gly188Glu Mutation in a Mexican Girl With Lipoprotein Lipase Deficiency
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Colima Fausto AG, González GarcÃa JR, Hernández Flores TDJ, Vázquez Cárdenas NA, SolÃs Perales NE, Magaña Torres MT
- KMID: 2376798
- Ann Lab Med.
- 2017 Jul;37(4):355-358.
- doi: 10.3343/alm.2017.37.4.355
No abstract available. -
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- A 1-month-old infant with chylomicronemia due to GPIHBP1 gene mutation treated by plasmapheresis
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Jung MK, Jin J, Kim HO, Kwon A, Chae HW, Kang SJ, Kim DH, Kim HS
- KMID: 2409803
- Ann Pediatr Endocrinol Metab.
- 2017 Mar;22(1):68-71.
- doi: 10.6065/apem.2017.22.1.68
Chylomicronemia is a severe type of hypertriglyceridemia characterized by chylomicron accumulation that arises from a genetic defect in intravascular lipolysis. It requires urgent and proper management, because serious cases can... -
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- Expression Levels of GABA-A Receptor Subunit Alpha 3, Gabra3 and Lipoprotein Lipase, Lpl Are Associated with the Susceptibility to Acetaminophen-Induced Hepatotoxicity
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Kim M, Yun JW, Shin K, Cho Y, Yang M, Nam KT, Lim KM
- KMID: 2375030
- Biomol Ther.
- 2017 Mar;25(2):112-121.
- doi: 10.4062/biomolther.2016.076
Drug-induced liver injury (DILI) is the serious and fatal drug-associated adverse effect, but its incidence is very low and individual variation in severity is substantial. Acetaminophen (APAP)-induced liver injury accounts... -
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- High maysin corn silk extract reduces body weight and fat deposition in C57BL/6J mice fed high-fat diets
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Lee EY, Kim SL, Kang HJ, Kim MH, Ha AW, Kim WK
- KMID: 2359613
- Nutr Res Pract.
- 2016 Dec;10(6):575-582.
- doi: 10.4162/nrp.2016.10.6.575
BACKGROUNG/OBJECTIVES: The study was performed to investigate the effects and mechanisms of action of high maysin corn silk extract on body weight and fat deposition in experimental animals. MATERIALS/METHODS: A total... -
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- Effect of Glucagon-like Peptide-1 on the Differentiation of Adipose-derived Stem Cells into Osteoblasts and Adipocytes
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Lee HM, Joo BS, Lee CH, Kim HY, Ock JH, Lee YS
- KMID: 2200986
- J Menopausal Med.
- 2015 Aug;21(2):93-103.
- doi: 10.6118/jmm.2015.21.2.93
OBJECTIVES: Glucagon-like peptide-1 (GLP-1) is an intestinally secreted hormone and it plays an important role in the regulation of glucose homeostasis. However, the possible role of GLP-1 in the differentiation... -
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- A study of the lipoprotein lipase inhibitory mechanism of Poncirus trifoliata water extracts
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Lee SM, Kang YH, Kim KK, Kim TW, Choe M
- KMID: 2327172
- J Nutr Health.
- 2015 Feb;48(1):9-18.
- doi: 10.4163/jnh.2015.48.1.9
PURPOSE: Poncirus trifoliata has been reported to have anti-inflammatory, antioxidant, and immune activities. However, its anti-obesity activity and the mechanism by which the water extract of dried, immature fruit of... -
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- Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet
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Min B, Lee H, Song JH, Han MJ, Chung J
- KMID: 2313792
- Nutr Res Pract.
- 2014 Dec;8(6):655-661.
- doi: 10.4162/nrp.2014.8.6.655
BACKGROUND/OBJECTIVES: The purpose of this study was to examine the effects and associated mechanisms of arctiin, a lignan compound found in burdock, on adipogenesis in 3T3-L1 cells. Also, the effects... -
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- Fenofibrate Therapy and Change of Renal Function: Management, What and How?
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Kim SH
- KMID: 2269333
- Korean J Med.
- 2014 Jun;86(6):698-701.
Fenofibrate is one of PPAR-alpha (peroxisome proliferator activated receptor alpha) agonists. Fenofibrate decreases effectively triglyceride and increases high density lipoprotein cholesterol level through the effect on lipoprotein lipase, hepatic production... -
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- Adipogenesis of Sprague Dawely rats mesenchymal stem cells: a morphological, immunophenotyping and gene expression follow-up study
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Sobh MA
- KMID: 1882578
- Anat Cell Biol.
- 2014 Jun;47(2):83-90.
- doi: 10.5115/acb.2014.47.2.83
Mesenchymal stem cells (MSCs) offer significant promise as a multipotent source for cell-based therapies and could form the basis for the differentiation and cultivation of tissue grafts to replace damaged... -
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- Gestational hyperlipidemia and acute pancreatitis with underlying partial lipoprotein lipase deficiency and apolipoprotein E3/E2 genotype
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Han DH, Moh IH, Kim DM, Ihm SH, Choi MG, Yoo HJ, Hong EG
- KMID: 1780111
- Korean J Intern Med.
- 2013 Sep;28(5):609-613.
- doi: 10.3904/kjim.2013.28.5.609
We report the case of a patient who experienced extreme recurrent gestational hyperlipidemia. She was diagnosed with partial lipoprotein lipase (LPL) deficiency but without an associated LPL gene mutation in... -
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- The Role of Androgen in the Adipose Tissue of Males
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Lee HK, Lee JK, Cho B
- KMID: 2320841
- World J Mens Health.
- 2013 Aug;31(2):136-140.
Adipose tissue, where various metabolic hormones are secreted, plays a role in metabolizing different substances including androgen. Within fat tissue, enzymes such as aromatase and aldo-keto reductase 1C are responsible... -
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- Clinical Factors Affecting Lipid Metabolism and Optimal Dose of Heparin in Preterm Infants on Parenteral Nutrition
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Lim MS, Choi CW, Kim BI, Yang HR
- KMID: 2315415
- Pediatr Gastroenterol Hepatol Nutr.
- 2013 Jun;16(2):116-122.
PURPOSE: Preterm infants on parenteral nutrition are at a relatively high risk for hypertriglyceridemia because they have immature lipoprotein lipase activity. The purpose of this study was to analyze the... -
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- Inhibitory effects of Capsicum annuum L. water extracts on lipoprotein lipase activity in 3T3-L1 cells
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Baek J, Lee J, Kim K, Kim T, Kim D, Kim C, Tsutomu K, Ochir S, Lee K, Park CH, Lee YJ, Choe M
- KMID: 2391960
- Nutr Res Pract.
- 2013 Apr;7(2):96-102.
Obesity, an intractable metabolic disease, currently has no medical treatment without side effects, so studies have been actively carried out to find natural compounds that have anti-obesity activity with minimum... -
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- Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study
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Pyun JA, Kim S, Park K, Baik I, Cho NH, Koh I, Lee JY, Cho YS, Kim YJ, Go MJ, Shim E, Kwack K, Shin C
- KMID: 2166490
- Genomics Inform.
- 2012 Jun;10(2):88-98.
- doi: 10.5808/GI.2012.10.2.88
Lipoprotein lipase (LPL) plays an essential role in the regulation of high-density lipoprotein cholesterol (HDLC) and triglyceride levels, which have been closely associated with cardiovascular diseases. Genetic studies in European... -
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