- Inhibitory effect of carvacrol on lipopolysaccharide-induced memory impairment in rats
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Lee B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2466567
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):27-37.
- doi: 10.4196/kjpp.2020.24.1.27
Neuroinflammation is an important process underlying a wide variety of neurodegenerative diseases. Carvacrol (CAR) is a phenolic monoterpene commonly used as a food additive due to its antibacterial properties, but... -
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- Effects of remifentanil preconditioning on factors related to uterine contraction in WISH cells
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Kim CH, Lee SH, Kim EJ, Ahn JH, Choi EJ, Yoon JU, Choi IS
- KMID: 2466649
- J Dent Anesth Pain Med.
- 2019 Dec;19(6):343-351.
- doi: 10.17245/jdapm.2019.19.6.343
BACKGROUND: Preterm labor and miscarriage may occur in stressful situations, such as a surgical operation or infection during pregnancy. Pharyngeal and buccal abscess and facial bone fractures are inevitable dental... -
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- Neutrophilic Granule Protein Is a Novel Murine LPS Antagonist
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Hong J, Qu P, Wuest TR, Huang H, Huang C, Lin PC
- KMID: 2461198
- Immune Netw.
- 2019 Oct;19(5):e34.
- doi: 10.4110/in.2019.19.e34
Neutrophilic granule protein (NGP) was previously reported as a granular protein of neutrophils in mouse, but the function has not been known clearly. We found the presence of the possible... -
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- Potential Roles of Innate Immune Chemokine and Cytokine Network on Lipopolysaccharide-Based Therapeutic Approach in Ovarian Cancer
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Ignacio RM, Lee ES, Son DS
- KMID: 2450207
- Immune Netw.
- 2019 Jun;19(3):e22.
- doi: 10.4110/in.2019.19.e22
Ovarian cancer (OC), the deadliest gynecological cancer, results in poor overall survival, urgently requiring a novel therapeutic approach. As cumulative exposures to endotoxins decreased OC risk epidemiologically, we evaluated if... -
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- The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury
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Jang EA, Kim JY, Tin TD, Song JA, Lee SH, Kwak SH
- KMID: 2449367
- Acute Crit Care.
- 2019 May;34(2):133-140.
- doi: 10.4266/acc.2019.00507
BACKGROUND: Overactivation of inflammatory cells, including macrophages and neutrophils, is associated with acute lung injury. BMS-470539 is a selective agonist of melanocortin 1 receptor, which triggers the inhibition of proinflammatory... -
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- Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells
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Jin Y, Baek N, Back S, Myung CS, Heo KS
- KMID: 2452068
- J Bacteriol Virol.
- 2018 Dec;48(4):156-165.
- doi: 10.4167/jbv.2018.48.4.156
Minor ginsenosides Rh1 and Rg2 were isolated from Korean red ginseng and reported to have various biological effects on anti-inflammatory and anti-stress activities. However, the effects of Rh1 and Rg2... -
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- Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model
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Huh JW, Kim WY, Park YY, Lim CM, Koh Y, Kim MJ, Hong SB
- KMID: 2436327
- Acute Crit Care.
- 2018 Aug;33(3):154-161.
- doi: 10.4266/acc.2018.00619
BACKGROUND: Mesenchymal stem cells (MSCs) attenuate injury in various lung injury models through paracrine effects. We hypothesized that intratracheal transplantation of allogenic MSCs could attenuate lipopolysaccharide (LPS)-induced acute lung injury... -
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- Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
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Bok E, Cho EJ, Chung ES, Shin WH, Jin BK
- KMID: 2419340
- Exp Neurobiol.
- 2018 Aug;27(4):309-319.
- doi: 10.5607/en.2018.27.4.309
The present study investigated the effects of interleukin (IL)-4 on dopamine (DA) neurons in the substantia nigra (SN) in vivo of lipopolysaccharide (LPS)-treated rat. Tyrosine hydroxylase immunohistochemistry showed a significant... -
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- Dysregulation of GABAergic Signalling Contributes in the Pathogenesis of Diarrhea-predominant Irritable Bowel Syndrome
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Aggarwal S, Ahuja V, Paul J
- KMID: 2417387
- J Neurogastroenterol Motil.
- 2018 Jul;24(3):422-430.
- doi: 10.5056/jnm17100
BACKGROUND/AIMS: Diarrhea-predominant irritable bowel syndrome (IBS-D) is a prevalent functional bowel disorder. Abdominal pain, discomfort and altered intestinal habits are the salient features of IBS-D. Low grade inflammation and altered... -
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- A Single Intraperitoneal Injection of Endotoxin Changes Glial Cells in Rats as Revealed by Positron Emission Tomography Using [¹¹C]PK11195
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Ota M, Ogura J, Ogawa S, Kato K, Matsuda H, Kunugi H
- KMID: 2414813
- Nucl Med Mol Imaging.
- 2018 Jun;52(3):224-228.
- doi: 10.1007/s13139-017-0510-9
PURPOSE: Intracranial administration of lipopolysaccharide (LPS) is known to elicit a rapid innate immune response, activate glial cells in the brain, and induce depression-like behavior. However, no study has focused... -
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- Up-regulation of IGF Binding Protein-3 Inhibits Colonic Inflammatory Response
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Kim SC, Hwang PH
- KMID: 2409215
- J Korean Med Sci.
- 2018 Mar;33(13):e110.
- doi: 10.3346/jkms.2018.33.e110
BACKGROUND: The aggravating factors still remained unclear in inflammatory bowel disease (IBD). Despite many different therapeutic approaches, many patients do not respond to the therapy. The anti-inflammatory effect of insulin-like... -
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- Mild encephalopathy with a reversible splenial lesion in a girl with acute pyelonephritis
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Yeom JS, Koo CM, Park JS, Seo JH, Park ES, Lim JY, Woo HO, Youn HS
- KMID: 2452043
- Korean J Pediatr.
- 2018 Feb;61(2):64-67.
- doi: 10.3345/kjp.2018.61.2.64
We report the case of a 12-year-old girl who had mild encephalopathy with a reversible splenial lesion (MERS) associated with acutepyelonephritis caused by Escherichia coli. The patient was admitted with... -
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- The Effects of Flecainide Acetate on Inflammatory-Immune Response in Lipopolysaccharide-Stimulated Neutrophils and on Mortality in Septic Rats
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Chung SY, Kim J, Bae HB, Tin TD, Ju W, Kwak SH
- KMID: 2436305
- Acute Crit Care.
- 2018 Feb;33(1):34-41.
- doi: 10.4266/acc.2017.00577
BACKGROUND: Flecainide acetate is a drug used primarily for cardiac arrhythmia. Some studies also imply that flecainide acetate has the potential to regulate inflammatory-immune responses; however, its mechanism of action... -
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- Effects of Macrolide and Corticosteroid in Neutrophilic Asthma Mouse Model
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An TJ, Rhee CK, Kim JH, Lee YR, Chon JY, Park CK, Yoon HK
- KMID: 2420594
- Tuberc Respir Dis.
- 2018 Jan;81(1):80-87.
- doi: 10.4046/trd.2017.0108
BACKGROUND: Asthma is a disease of chronic airway inflammation with heterogeneous features. Neutrophilic asthma is corticosteroid-insensitive asthma related to absence or suppression of TH2 process and increased TH1 and/or TH17... -
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- Effect of Rifaximin on Hepatic Fibrosis in Bile Duct-ligated Rat Model
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Shin SK, Kwon OS, Lee JJ, Park YH, Choi CS, Jeong SH, Choi DJ, Kim YS, Kim JH
- KMID: 2398870
- Korean J Gastroenterol.
- 2017 Nov;70(5):239-246.
- doi: 10.4166/kjg.2017.70.5.239
BACKGROUND/AIMS: The translocation of bacteria and their lipopolysaccharides from the gut can promote fibrosis in cirrhotic patients. The aim of this study was to investigate the effects of rifaximin on... -
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- A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells
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Jang J, Yoon Y, Oh DJ
- KMID: 2416091
- Kidney Res Clin Pract.
- 2017 Sep;36(3):224-231.
- doi: 10.23876/j.krcp.2017.36.3.224
BACKGROUND: Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif and is produced by endothelial cells stimulated with lipopolysaccharide (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon-γ. There... -
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- Animal Models for Acute Kidney Injury
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Jang HR
- KMID: 2392417
- J Korean Soc Transplant.
- 2017 Sep;31(3):111-116.
- doi: 10.4285/jkstn.2017.31.3.111
Acute kidney injury (AKI) is classified into three types according to its pathophysiology: prerenal, intrinsic renal, and post-renal AKI. Experimental models of AKI can be divided into two categories: in... -
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- Establishment of minimal positive-control conditions to ensure brain safety during rapid development of emergency vaccines
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Baek H, Kim KH, Park MY, Kim K, Ko B, Seo HS, Kim BS, Hahn TW, Yi SS
- KMID: 2412562
- J Vet Sci.
- 2017 Aug;18(S1):371-379.
- doi: 10.4142/jvs.2017.18.S1.371
With the increase in international human and material exchanges, contagious and infectious epidemics are occurring. One of the effective methods of epidemic inhibition is the rapid development and supply of... -
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- Changes in serum levels of lipopolysaccharides and CD26 in patients with Crohn's disease
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Magro DO, Kotze PG, Martinez C, Camargo MG, Guadagnini D, Calixto AR, Vasques AC, Ayrizono M, Geloneze B, Pareja JC, Saad MJ, Coy CS
- KMID: 2382379
- Intest Res.
- 2017 Jul;15(3):352-357.
- doi: 10.5217/ir.2017.15.3.352
BACKGROUND/AIMS: Lipopolysaccharide (LPS) is a molecule formed by lipids and polysaccharides and is the major cell wall component of gram-negative bacteria. High LPS levels are known to block CD26 expression... -
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- Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome
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RodrÃguez-Fandiño OA, Hernández-Ruiz J, López-Vidal Y, Charúa-Guindic L, Escobedo G, Schmulson
- KMID: 2433529
- J Neurogastroenterol Motil.
- 2017 Apr;23(2):281-288.
- doi: 10.5056/jnm16137
BACKGROUND/AIMS: Abnormal immune regulation and increased intestinal permeability augmenting the passage of bacterial molecules that can activate immune cells, such as monocytes/macrophages, have been reported in irritable bowel syndrome (IBS).... -
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