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Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity

Yoon SP, Kim J

Enhanced oxidative stress is a hallmark of cisplatin nephrotoxicity, and inhibition of poly(ADP-ribose) polymerase 1 (PARP1) attenuates oxidative stress during cisplatin nephrotoxicity; however, the precise mechanisms behind its action remain...
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Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells

Park S, Yoon SP, Kim J

Treatment with cisplatin for cancer therapy has a major side effect such as nephrotoxicity; however, the role of poly (ADP-ribose) polymerase 1 (PARP1) in necrosis in response to cisplatin nephrotoxicity...
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Beneficial Antioxidative and Antiperoxidative Effect of Cinnamaldehyde Protect Streptozotocin-Induced Pancreatic beta-Cells Damage in Wistar Rats

Subash-Babu P, Alshatwi A, Ignacimuthu S

  • KMID: 2048330
  • Biomol Ther.
  • 2014 Jan;22(1):47-54.
The present study was aimed to evaluate the antioxidant defense system of cinnamaldehyde in normal, diabetic rats and its possible protection of pancreatic beta-cells against its gradual loss under diabetic...
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Hepatotoxicity in Rats Treated with Dimethylformamide or Toluene or Both

Kim KW, Chung YH

  • KMID: 2317834
  • Toxicol Res.
  • 2013 Sep;29(3):187-193.
The effects of toluene in dimethylformamide (DMF)-induced hepatotoxicity were investigated with respect to the induction of cytochrome P-450 (CYP) and the activities of related enzymes. The rats were treated intraperitoneally...
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Suppression of oxidative stress by grape seed supplementation in rats

Choi SK, Zhang XH, Seo JS

  • KMID: 2313568
  • Nutr Res Pract.
  • 2012 Feb;6(1):3-8.
Polyphenol-rich grape seeds have a beneficial effect on human health. The present study was performed to investigate the effects of grape seeds on antioxidant activities in rats. Male Sprague-Dawley rats...
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Anti-atherosclerotic Effect of Green Tea in Poluynsaturated Fatty Acids-treated Apo E KO Mice

Kim HS, Lee M

Dietary fatty acids are under intense research to identify anti-atherogenic mechanisms, so we investigated green tea powder (GT) as a protector against atherogenesis originating from lipid peroxidation such as 4-hydroxynonemal...
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Maternal serum levels of C-reactive protein and placental levels of IL-6, lipid peroxide, and protein carbonyl in preterm birth according to histologic chorioamnionitis

Yoon DS, Kim YH, Kim CH, Cho MK, Kim JW, Cho HY, Kim SM, Kang WD, Lee KH, Song TB

OBJECTIVE: To evaluate predictive value of maternal serum white blood cells (WBCs), C-reactive protein (CRP) levels, placental interleukin-6 (IL-6), lipid peroxide, and protein carbonyl levels in preterm birth according to...
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The Effect of Isoflavone and Gamma-linolenic Acid Supplementation on Serum Lipids and Menopausal Symptoms in Postmenopausal Women

Gwak JH, Kim JY, Kim HJ, Shin DH, Lee JH

This study was performed to examine the combined effects of gamma linolenic acid and isoflavone supplementation on menopausal symptoms and serum lipids in 73 postmenopausal women. A total subjects were...
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Antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes mellitus

Lee YM, Gweon OC, Seo YJ, Im J, Kang MJ, Kim MJ, Kim JI

  • KMID: 2313392
  • Nutr Res Pract.
  • 2009 Jun;3(2):156-161.
Hyperglycemia in the diabetic state increases oxidative stress and antioxidant therapy can be strongly correlated with decreased risks for diabetic complications. The purpose of this study is to determine antioxidant...
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Changes of antioxidant levels in the uterine venous plasma amniotic fluid, and chorioamnion after maternal supplementation with vitamin C and vitamin E

Yang JS, Kim YH, Kim CH, Cho MK, Kim JW, Cho HY, Yang SY, Ahn BW, Nam JH, Song TB

  • KMID: 1980191
  • Korean J Perinatol.
  • 2009 Mar;20(1):17-26.
PURPOSE:To investigate the change in the antioxidant vitamin levels in maternal uterine venous plasma (MUVP), amniotic fluid (AF), and chorioamnion after vitamin C and E supplementation during pregnancy. METHODS:Thirty pregnant women...
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Effect of Vitamin E Supplementation on Lipid Peroxide Levels of Blood and Liver in Zinc Deficient Rats

Lee KJ, Lee EH, Chyun JH

  • KMID: 2261877
  • Korean J Nutr.
  • 2008 Jun;41(4):291-298.
To study antioxidant role of zinc, the effects of dietary zinc deficiency and vitamin E supplementation on lipid peroxidation were studied. Levels of zinc and vitamin E in blood and...
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The change of lipid peroxidation and superoxide dismutase activity in placenta by the birth to placental weight ratio at birth

Kim JE, Jin K

  • KMID: 1992890
  • Korean J Obstet Gynecol.
  • 2008 Apr;51(4):391-398.
OBJECTIVE: The object of this study is to determine whether there is any association between birth to placenta weight ratio and oxidative stress. 34 pregnant women (who gave birth after...
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Effects of Chongkukjang Intake on Lipid Metabolism and Liver Function in Ethanol Consumed Rats

Lee EH, Chyun JH

  • KMID: 2260667
  • Korean J Nutr.
  • 2007 Dec;40(8):684-692.
This study was performed to investigate the effect of chongkukjang intake on lipid metabolism and liver function in ethanol consumed rats. Twenty one Sprague-Dawley male rats aging 4 weeks old...
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Changes in the Total Antioxidant Ability and Antioxidant Vitamin Levels in the Maternal Venous Plasma of Preeclampsia

Jeon YM, Yang JS, Park YJ, Kim YH, Kim CH, Jo MK, Kim KM, Kim JW, Song TB, Ahn BW, Yang SY

  • KMID: 2272599
  • Korean J Obstet Gynecol.
  • 2005 May;48(5):1202-1210.
OBJECTIVE: This study was aimed to compare lipid peroxide level, total peroxyl radical-trapping antioxidative parameter (TRAP) value, and antioxidant vitamin level in the maternal venous plasma between normal pregnancy and...
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Effects of beta-Carotene Supplementation on Lipid Peroxide Levels and Antioxidative Enzyme Activities in Alcoholic Fatty Liver Rats

Lee EH, Chyun JH

  • KMID: 2257564
  • Korean J Nutr.
  • 2005 May;38(4):289-296.
This study was performed to investigate the effect of dietary beta-carotene supplementation on lipid peroxide levels and antioxidant enzyme activities in alcoholic fatty liver rats. Forty five Sprague-Dawley male rats...
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The Relationship between Serum Creatinine Concentrations and Oxidative Stress or Plasma Levels of Inflammatory Cytokine after Living Donor Renal Transplantation

Kim JH, Park J, Kim MS, Ha H, Kim YS

  • KMID: 2096256
  • J Korean Surg Soc.
  • 2005 May;68(5):414-421.
PURPOSE: Increased oxidative stress and chronic inflammatory process have been substantially linked with the development and progression of chronic renal failure. However, the roles of oxidative stress and inflammation in...
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Effect of beta-carotene Supplementation on Lipid Peroxides and Antioxidative Enzyme Activities in Hyperlipidemic Rats

Song YO, Chyun JH

  • KMID: 2269801
  • Korean J Nutr.
  • 2004 Nov;37(9):771-779.
This study was performed to investigate the effect of dietary beta-carotene supplementation on lipid metabolism and antioxidant enzyme activities in hyperlipidemic rats. Fifty Sprague-Dawley male rats aging 7 weeks were...
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Age-Related Changes of Lipid Metabolism and Thrombogenic Capacity in Rats

Um MY, Rho KA, Kim MK

  • KMID: 2269793
  • Korean J Nutr.
  • 2004 Sep;37(7):525-532.
This study was performed to investigate the age-related changes of the lipid metabolism and thrombogenic capacity in Sprague-Dawley (SD) rats at the ages of 4, 8, 12, 16, 20 and...
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Effect of CLA (Conjugated Linoleic Acid) on the Anti-Atherosclerotic Factors in Human Hepatoma HepG2 Cells

Oh H, Mun H, Lee M

  • KMID: 2269778
  • Korean J Nutr.
  • 2004 Apr;37(3):182-192.
Conjugated linoleic acid (CLA) is the mixture of positional and geometric isomers of linoleic acid (LA), which is found abundantly in dairy products and meats. This study was performed to...
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The Expression of Nuclear Factor-kappaB in the Placental Tissue with Preeclampsia

Yoo SC, Byun YJ, Yang JI, Joo HJ, Kim HS, Ryu HS

  • KMID: 1609580
  • Korean J Perinatol.
  • 2004 Mar;15(1):19-26.
OBJECTIVE: The aim of this study is to ascertain the differences in NF-kappaB (Nuclear Factor-kappa B : p50) activity between the placental tissues of preeclampsia and normal pregnancy, and to...
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