- Acute toxicity of benzalkonium chloride in Balb/c mice following intratracheal instillation and oral administration
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Lee H, Park K
- KMID: 2470821
- Environ Anal Health Toxicol.
- 2019 Sep;34(3):e2019009.
- doi: 10.5620/eaht.e2019009
Benzalkonium chloride is a cationic surfactant widely used as a disinfectant, preservative, and sanitizer in many public places as well as domestically. The purpose of this study is to compare... -
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- The Effect of Diphenylhydantoin on the Action of Ouabain
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Kang SK, Park OK
- KMID: 2229702
- Korean Circ J.
- 1971 Dec;1(2):23-26.
- doi: 10.4070/kcj.1971.1.2.23
The effect of diphenylhydantoin on LD 50 of ouabain was investigated in frogs, using "one hour frog method". LD50 of ouabain in control group was 1.90 microg/10g. A dose of... -
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- Metoclopramide protection of diazinon-induced toxicosis in chickens
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Al-Zubaidy MH, Mohammad F
- KMID: 1090799
- J Vet Sci.
- 2007 Sep;8(3):249-254.
- doi: 10.4142/jvs.2007.8.3.249
The efficacy of metoclopramide for preventing organo-phosphate insecticide-induced (diazinon) toxicosis wasevaluated in 7~14 days old chicks. Injection of metoclo-pramide at 25mg/kg, s.c. 15min before diazinon increasedthe oral 24 h median... -
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- Acute Toxicity of Arsenic in Rats and Mice
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Choi BS, Kang DW, Lee JY, Park ES, Hong YP, Yang JS, Lee H, Park JD
- KMID: 2141557
- Korean J Occup Environ Med.
- 2003 Dec;15(4):323-334.
OBJECTIVES: Arsenic (As) is ubiquitously distributed in the environment and is known as a human carcinogen. In this study, acute As toxicity at lethal dosage in rats and mice was... -
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- Toxicity of Methylcyclohexane and Its Effect on the Reproductive System in SD Rats
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Kim HY, Kang MG, Kim TG, Kang CW
- KMID: 2317026
- Saf Health Work.
- 2011 Sep;2(3):290-300.
OBJECTIVES: There is limited data regarding the toxicity of methylcyclohexane, despite its wide use in rubber adhesives, paint diluents, and cleansing agents. This study aimed to verify the toxicity and... -
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- Helicobacter pylori Urease Induces Mouse Death
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Baik SC, Kang HL, Seo JH, Park ES, Rhee KH, Cho MJ
- KMID: 1574158
- J Bacteriol Virol.
- 2005 Sep;35(3):175-181.
The component of Helicobacter pylori responsible for mouse death was identified and partially characterized. Mice that were injected with H. pylori cell lysate showed pathological changes such as decreased activity,... -
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- Mouse Single Oral Dose Toxicity Test of Bupleuri Radix Aqueous Extracts
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Kim KH, Gam CO, Choi SH, Ku SK
- KMID: 2052546
- Toxicol Res.
- 2012 Mar;28(1):11-18.
The aim of this study was to evaluate the single oral dose toxicity of Bupleuri Radix (BR) aqueous extracts, it has been traditionally used as anti-inflammatory agent, in male and... -
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- Primary Isolate S-352, a Novel Clone of Salmonella typhi, shows Strong Viability in Macrophage
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Bae YS, Jo SK, Lee KJ, Ju YR, Lim JY, Kim YC
- KMID: 1943460
- J Korean Soc Microbiol.
- 1997 Apr;32(2):167-174.
In order to develop a multivalent vaccine from a primary isolate against enteric bacterial diseases, several candidates were selected from the recent enteric patients in Korea. Among the 120 pathogenic... -
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- Foeniculum vulgare as Valuable Plant in Management of Women's Health
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Mahboubi M
- KMID: 2443622
- J Menopausal Med.
- 2019 Apr;25(1):1-14.
- doi: 10.6118/jmm.2019.25.1.1
This review paper evaluates use of Foeniculum vulgare extracts as a popular female plant in management of different ailments of women. Information in this paper was gathered from accessible sources... -
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- Changes of characterization of Salmonella Typhimurium isolate following sequential exposures to porcine neutrophil
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Lee HS, Kim A, Youn M, Lee JY, Lim SK, Kang HY, Yoo HS, Park JW, Wee SH, Jung SC
- KMID: 1991790
- Korean J Vet Res.
- 2013 Mar;53(1):29-35.
To develop a live vaccine candidate using an attenuated strain of Salmonella Typhimurium (ST), biochemical properties, plasmid profile, PFGE patterns and pathogenic analysis of the ST isolate were carried out... -
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- A serine/threonine phosphatase 1 of Streptococcus suis type 2 is an important virulence factor
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Fang L, Zhou J, Fan P, Yang Y, Shen H, Fang W
- KMID: 2398502
- J Vet Sci.
- 2017 Dec;18(4):439-447.
- doi: 10.4142/jvs.2017.18.4.439
Streptococcus suis is regarded as one of the major pathogens of pigs, and Streptococcus suis type 2 (SS2) is considered a zoonotic bacterium based on its ability to cause meningitis... -
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- Testicular Cytotoxicity of Intraperitoneal Thio-TEPA in Mice
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Jun BW, Cho YH
- KMID: 2289542
- Korean J Urol.
- 1988 Feb;29(1):9-15.
Mice were used to evaluate the adverse testicular effects of anticancer agents. Testicular cytotoxicity of many chemotherapeutic drugs has been evaluated in mice. In this report, we described thio-TEPA induced... -
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- Acute Oral or Dermal and Repeated Dose 90-Day Oral Toxicity of Tetrasodium Pyrophosphate in Spraque Dawley (SD) Rats
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Seo DS, Kwon M, Sung HJ, Park CB
- KMID: 2380164
- Environ Health Toxicol.
- 2011 ;26(1):e2011014.
OBJECTIVES: Tetrasodium pyrophosphate (TSP) is used in processed meat products, as an emulsifier in cheese, and as a color preservative in soybean paste. However, little is known about its toxicity.... -
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- Biological Activity and Single Oral Dose Toxicity of Dansam-samultang
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Lee IC, Kim BH, Kim MK
- KMID: 2114707
- Lab Anim Res.
- 2010 Dec;26(4):385-391.
- doi: 10.5625/lar.2010.26.4.385
In this study, we investigated the in vitro antioxidative effects, antimicrobial activities and single oral dose toxicity of the extracts from Dansam-samultang to evaluate its use as a functional ingredient... -
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- Anthelmintic efficacy of extracts of Spigelia anthelmia Linn on experimental Nippostrongylus braziliensis in rats
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Jegede OC, Ajanusi JO, Adaudi AO, Agbede RI
- KMID: 1089906
- J Vet Sci.
- 2006 Sep;7(3):229-232.
- doi: 10.4142/jvs.2006.7.3.229
Spigelia anthelmia Linn is used as a herb and is a common annual weed of cultivation in open re-growths, on unused land in towns as well as on road sides.... -
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- Investigations of Samwhang-sasimtang Extracts on Biological Activities In Vitro and Vivo
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Lee IC, Kim BH, Kim MK
- KMID: 1458935
- Lab Anim Res.
- 2010 Mar;26(1):15-20.
- doi: 10.5625/lar.2010.26.1.15
In this study, we investigated the in vitro antioxidative effects, antimicrobial activities and single oral dose toxicity of the extracts from Samwhang-sasimtang to evaluate its use as a functional ingredient... -
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- Experimental Study for Rabbit Corneal Epithelial Toxicity of MMC
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Jung DY, Lee JS
- KMID: 2336821
- J Korean Ophthalmol Soc.
- 1999 Apr;40(4):926-932.
We studied the biological effects of Mitomycin C(MMC) in cellular metabolic activity and cytotoxicity on the corneal epithelial cell in rabbit that is clinically used according to MMC concentrations and... -
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- Efficacy of Purified Vi Polysaccharide Typhoid Vaccine
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Park JH, Hong JJ, Choi ES, Lee JW, Park JH
- KMID: 1095363
- J Vet Sci.
- 2002 Jun;3(2):67-70.
This experiment was conducted to assess the efficacy of typhoid vaccine newly produced by purifying Vi antigen of Salmonella typhi. With Karber method, LD50 of challenging organism (S. typhi ty2)... -
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- Characteristic profiles of biofilm, enterotoxins and virulence of Staphylococcus aureus isolates from dairy cows in Xinjiang Province, China
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Wu Y, Li J, Qiao M, Meng D, Meng Q, Qiao J, Zhang X, Wang L, Cai K, Zhang J, Zhang Z, Yu W, Cai X
- KMID: 2464089
- J Vet Sci.
- 2019 Nov;20(6):e74.
- doi: 10.4142/jvs.2019.20.e74
As an important zoonotic pathogen, Staphylococcus aureus has led to serious mastitis and endometritis in infected dairy cows. In this study, a total of 164 strains of S. aureus were... -
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- Comparative acute toxicity of quaternary ammonium lidocaine derivative QX-314 to lidocaine in mice
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Lee SM, Chung KD, Son YS, Yu SJ, Ryu KH, Lee SH, Cho HS
- KMID: 2263347
- Anesth Pain Med.
- 2009 Jan;4(1):5-10.
BACKGROUND: The current study examined the acute systemic toxicity of QX-314 that there have been few research results for this so far. In order to be useful as a drug,... -
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