- Diagnostic Classification and Genomic Analyses of Cancer
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Kim JW
- KMID: 2526079
- Lab Med Online.
- 2021 Oct;11(4):223-229.
- doi: 10.47429/lmo.2021.11.4.223
Diagnostic classification of diseases is fundamental to disease diagnosis and treatment. Cancers have traditionally been classified based on histopathology, but cancer is defined as a genetic disease. Emerging genetic knowledge... -
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- Initial Response of the Korean Society for Laboratory Medicine to the COVID-19 Pandemic
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Yun SG, Ko DH, Kim YE, Roh KH, Lee J, Cho JH, Ji M, Hong KH, Park HD, Kwon GC
- KMID: 2526078
- Lab Med Online.
- 2021 Oct;11(4):217-222.
- doi: 10.47429/lmo.2021.11.4.217
The coronavirus disease (COVID-19) pandemic originated in Wuhan, China, at the end of 2019. The cause of COVID-19 is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus phylogenetically... -
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- Significance of Y Chromosome Loss in Hematologic Malignancies
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Kwak MS, Jeong IH, Kim WJ, Choi HW, Han JY
- KMID: 2526081
- Lab Med Online.
- 2021 Oct;11(4):230-234.
- doi: 10.47429/lmo.2021.11.4.230
Loss of chromosome Y (-Y) is one of the most common somatic genomic alterations in the male hematopoietic system. However, it has been widely debated whether -Y is an aging-related... -
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- Comparison of Three Automated Calcitonin Immunoassays for Evaluating the Equivalence Near the Clinical Decision Point
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Song J, Cho Y, Lee SG
- KMID: 2526084
- Lab Med Online.
- 2021 Oct;11(4):235-244.
- doi: 10.47429/lmo.2021.11.4.235
Background: To date, only a few studies have focused on the standardization of the calcitonin assay, despite the fact that a lack of standardization of assays can lead to discrepancy... -
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- Evaluation of the AccuPower® RV1 Real-Time RT-PCR Kit and the AccuPower® RV1 Multiplex Kit for SARS-CoV-2 and Influenza Virus Detection
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Kim MJ, Park H, Jeon YL, Shin HS, Cho SI, Kim B, Lee JS, Park SS, Seong MW
- KMID: 2526091
- Lab Med Online.
- 2021 Oct;11(4):290-296.
- doi: 10.47429/lmo.2021.11.4.290
Background: The AccuPower® RV1 Real-Time RT-PCR Kit (Bioneer, Korea) and AccuPower® RV1 Multiplex Kit (Bioneer) are one-step real-time reverse transcription PCR assays for detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)... -
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- Evaluation of a Targeted Next-generation Sequencing Assay for BRCA Mutation Screening in Clinical Samples
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Kim MJ, Song BJ, Kim SE, Lee CS, Im JE, Oh E, Lee K, Cho SI, Kim KJ, Park SS, Seong MW
- KMID: 2526090
- Lab Med Online.
- 2021 Oct;11(4):283-289.
- doi: 10.47429/lmo.2021.11.4.283
Background: While several factors contribute to breast cancer pathogenesis, hereditary breast cancer results from a genetic predisposition. Genes associated with hereditary breast cancer may be divided into high- and low-penetrance genes... -
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- Gastric Signet Ring Cell Carcinoma with Metastasis to the Bone and Bone Marrow in a Patient with 12-Year-Disease-Free Interval and Unusually Long Survival Time
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Kim HW, Gu MJ, Lee JH
- KMID: 2526093
- Lab Med Online.
- 2021 Oct;11(4):305-310.
- doi: 10.47429/lmo.2021.11.4.305
Gastric cancer (GC) is the second most common malignancy in Korea. Most deaths are due to disease recurrence; hence, efforts have been made to identify the recurrence patterns and establish... -
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- Performance Evaluation of the CareGENETM Zika Virus Reverse Transcription-PCR Kit for Urine Specimen
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Kim GW, Park BG, Kwak SY, Jang WS, Nam J, Lim CS
- KMID: 2526088
- Lab Med Online.
- 2021 Oct;11(4):267-274.
- doi: 10.47429/lmo.2021.11.4.267
Background: Zika virus (ZIKV) is a major health concern worldwide, highlighting the importance of accurate and reliable viral detection to control transmission. The careGENETM ZIKV Reverse Transcription-Polymerase Chain Reaction (RT-PCR)... -
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- Analysis of the Current Status of Liver Cancer Screening Institutions and Proficiency of Institutions that Conduct Alpha-fetoprotein Tests
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Lee JK, Kim TS, Song J, Lee WI, Jang D, Kim Y, Suh M, Chun S, Park HD
- KMID: 2526086
- Lab Med Online.
- 2021 Oct;11(4):245-253.
- doi: 10.47429/lmo.2021.11.4.245
Background: We sought to evaluate the performance of alpha-fetoprotein (AFP) qualitative reagents and understand the current status of AFP testing by liver cancer screening institutions. Methods: Using commercial control materials or... -
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- Detection of Circulating Tumor Cells Using Three-dimensional and Conditionally Reprogrammed Culture Methods
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Park C, Jeong YJ, Park SH, Kim DD, Jeon CH
- KMID: 2526092
- Lab Med Online.
- 2021 Oct;11(4):297-304.
- doi: 10.47429/lmo.2021.11.4.297
Background: Circulating tumor cells (CTCs) are rare in the circulation of patients with tumors and are very difficult to detect. In this study, we cultured CTCs in a three-dimensionally reprogrammed... -
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- Evaluation of Clinical and Analytical Performance of a Nucleocapsid Protein Antigenbased ELISA for Detecting Antibodies against SARS-CoV-2
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Suh IB, Kim H, Kim CE, Park JC, Kim S, Mihn DC
- KMID: 2526089
- Lab Med Online.
- 2021 Oct;11(4):275-282.
- doi: 10.47429/lmo.2021.11.4.275
Background: As the coronavirus disease 2019 (COVID-19) pandemic evolves, the development of immunoassays that will help assess population exposure and potentially predict immunity has become a pressing priority. Methods: We evaluated... -
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- Evaluation of Matrix Effect in Body Fluid Chemistry on Roche Cobas 8000 c702 System
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Seo JD, Li C, Kim S, Nam Y, Lee JH, Lee K, Song J, Song SH
- KMID: 2526087
- Lab Med Online.
- 2021 Oct;11(4):254-266.
- doi: 10.47429/lmo.2021.11.4.254
Background: Analysis of body fluids aids in diagnosis and monitoring disease. However, only a few testing platforms and reagents have been validated for a range of body fluids or analytes.... -
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