- Angiogenic Factors and Their Receptors
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Koh GY
- KMID: 1568684
- J Korean Soc Endocrinol.
- 2001 Jun;16(3):277-283.
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- Expressions of Angiopoietins-1 and -2 and their Relations with the Stage in Gastric Adenocarcinoma
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Lee WS, Choi SK, Rew JS, Kim SJ, Kim YJ, Park CS, Koh GY, Choi C
- KMID: 2085015
- Korean J Gastroenterol.
- 2002 May;39(5):335-342.
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- Plasma Angiotensin - Converting Enzyme Activity, NAG, Renin and Atrial Natriuretic Peptide in Korean Male Subjects
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Lee JH, Kim SH, Song HS, Han SH, Cho KW, Koh GY
- KMID: 2462158
- J Korean Soc Endocrinol.
- 1994 Mar;9(1):18-24.
The purpose of the present study was to define the normal range of plasma concentration of angiotensin I-converting enzyme(ACE), N-acetyl-b-D-glucosaminidase(NAG), inactive and active renin, and atrial natriuretic peptide(ANP) in normal... -
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- Cell cycle regulators during human atrial development
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Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK
- KMID: 759076
- Korean J Intern Med.
- 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)... -
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- Activation of PPARgamma induces profound multilocularization of adipocytes in adult mouse white adipose tissues
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Koh YJ, Park BH, Park JH, Han J, Lee IK, Park JW, Koh GY
- KMID: 1099865
- Exp Mol Med.
- 2009 Dec;41(12):880-895.
- doi: 10.3858/emm.2009.41.12.094
We sought to determine the effects of activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on multilocularization of adipocytes in adult white adipose tissue (WAT). Male C57BL/6 normal, db/db, and ob/ob mice... -
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- Alteration of Insulin-like Growth Factor ( IGF ) -I and IGP-Binding Proteins in Renal Development and Regeneration
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Lee DY, Park SK, Koh GY
- KMID: 2001746
- J Korean Soc Pediatr Nephrol.
- 1999 Oct;3(2):109-116.
The effect of Roentgen rays on carcinoma of the cervix has long been of great interest to both radiologists and gynecologists. Since most cervical carcinomas are treated by irradiation, any... -
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- Biomedical significance of endothelial cell specific growth factor, angiopoietin
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Koh GY, Kim I, Kwak HJ, Yun MJ, Leem JC
- KMID: 1093591
- Exp Mol Med.
- 2002 Mar;34(1):1-11.
Until recently, vascular endothelial growth factor (VEGF) was the only growth factor proven to be specific and critical for blood vessel formation. Other long-known factors, such as the fibroblast growth... -
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- Gene Ploymorphisms of Angiotensin Converting Enzyme and Endothelial Nitric Oxide Synthase in Patients with IgA Nephropathy
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Kim IH, Kim W, Kang SK, Lee DY, Koh GY, Lee KY, Park SB, Kim HC, Park SK
- KMID: 2307327
- Korean J Nephrol.
- 1999 May;18(3):390-399.
To evaluate the association between ACE gene I/D polymorphism and ecNOS gene a/b polymorphism in IgA nephropathy, 158 IgA nephropathy patients and 121 control subjects were examined. In genotype... -
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- Changes of atrial natriuretic peptide level in patients with nephrotic syndrome after supine bicycle exercise
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Park SK, Lee H, Park TS, Baek HS, Kang SK, Koh GY, Kim SH, Cho KW
- KMID: 1038460
- Korean J Intern Med.
- 1996 Jan;11(1):18-24.
OBJECTIVES: The exact role of atrial natriutetic peptide (ANP) in the pathogenesis of edema in nephrotic syndrome (NS) has not been fully elucidated. We aimed to investigate the possible contribution... -
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- The Synthesis and Distribution of TGF-beta1 in Cardiac Valves
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Ko JK, Kim NG, Kim MH, Chae JK, Koh GY
- KMID: 2228864
- Korean Circ J.
- 1998 Jul;28(7):1161-1167.
- doi: 10.4070/kcj.1998.28.7.1161
BACKGROUND AND OBJECTIVES: Transforming growth factor-beta1 (TGF-beta1) plays an important role on cardiac muscle differentiation, cardiac septa and valve formation during heart development. However, the role of TGF-beta1 in cardiac... -
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- Relationship of Angiopoietin-2 Expression to Atherosclerosis in Middle Cerebral and Coronary Arteries
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Shin EK, Park JW, Park MC, Kim CW, Ahn JS, Park KH, Kim DJ, Hahn JH, Koh GY, Park JH
- KMID: 1510193
- Korean J Anat.
- 2006 Aug;39(4):269-278.
Atherosclerosis is a systemic and multifactorial disease, its incidence is raised recently. Cerebral and coronary atherosclerosis have some similar pathogenesis, but their relationship and mechanisms are still remain unclear. Intimal neovascularization in... -
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- The Antiapoptotic Effect of Vascular Endothelial Growth Factor and Angiopoietin-1 on Glomerular Endothelial Cells in Adriamycin or Cisplatin-induced Apoptosis
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Kim W, Lim CS, Sung MJ, Kim SH, Moon SO, Lee S, La BJ, Park SK, Kang SK, Kim HJ, Koh GY
- KMID: 2254393
- Korean J Nephrol.
- 2002 Jul;21(4):569-583.
BACKGROUND: Because glomerular endothelium play a pivotal role in the renal diseases, damage of glomerular endothelial cells lead to progression of glomerular sclerosis and decrement of renal function. Apoptotic damage... -
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- COMP-angiopoietin 1 Gene Transfer Enhances Cutaneous Wound Healing by Promoting Angiogenesis
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Kim YY, Kim YJ, Ku JK, Kim MY, Kim YI, Koh GY, Kim HO, Park YM
- KMID: 2172084
- Ann Dermatol.
- 2008 Jun;20(2):49-55.
- doi: 10.5021/ad.2008.20.2.49
BACKGROUND: Angiogenesis is crucial for wound healing and exogenous supplements of the angiogenic growth factors have been known to promote cutaneous wound healing. Angiopoietin (Ang) 1 is a recently discovered... -
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- Angiotensin Converting Enzyme Gene Polymorphism in Patients with Minimal Change Nephrotic Syndrome and Focal Segmental Glomerulosclerosis
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Kim W, Park SK, Kang SK, Koh GY, Song SK, Lee KY, Chung WY, Kim PK, Lee DY
- KMID: 2254668
- Korean J Nephrol.
- 1998 Mar;17(2):208-213.
Angiotensin converting enzyme gene insertion/ deletion polymorphism has been shown to be associated with cardiovascular disease including cardiomyopathy, myocardial infarction, essential hypertension, progression of IgA nephropathy and diabetic nephropathy. Since... -
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- Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1
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Lee KS, Lee KY, Kim SR, Park HS, Park SJ, Min KH, Cho CH, Koh GY, Park HS, Lee YC
- KMID: 1091068
- Exp Mol Med.
- 2007 Dec;39(6):733-745.
Inflammation of the asthmatic airway is usually accompanied by increased vascular permeability and plasma exudation. Angiopoietin-1 (Ang1) has potential therapeutic applications in preventing vascular leakage. Recently, we developed a soluble,... -
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- Pathophysiological Role of Angiopoietin-2 in Human Coronary Atherosclerosis
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Shin EK, Park MC, Lee JH, Kim DJ, Hahn JH, Park KH, Koh GY, Park JH
- KMID: 1564364
- Korean J Anat.
- 2005 Aug;38(4):295-306.
Neovascularization is well known to occur in human atherosclerotic plaques; however, its pathophysiological roles, mechanism, and stimuli still remain unclear. Angiopoietin-1 and -2 belong to another vascular-specific growth factor family... -
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- Angiopoietin-1 Gene Therapy Attenuates Hypertension and Target Organ Damage in Nitric Oxide Synthase Inhibited Spontaneously Hypertensive Rats
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Suh W, Lee JS, Kim KL, Song SH, Koh GY, Kim DK
- KMID: 2297918
- Korean Circ J.
- 2011 Oct;41(10):590-595.
- doi: 10.4070/kcj.2011.41.10.590
BACKGROUND AND OBJECTIVES: In our previous study, we found that the gene transfer of a potent derivative of cartilage oligomeric matrix protein Angiopoietin-1 (COMP-Ang-1) substantially prevented hypertension, microvascular rarefaction, and... -
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- Angiopoietin-1 Protects Endothelial Cells From Hypoxia-Induced Apoptosis via Inhibition of Phosphatase and Tensin Homologue Deleted From Chromosome Ten
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Lee SW, Youn SW, Kim TY, Suh JW, Koh GY, Kwon YW, Chae IH, Park YB, Kim HS
- KMID: 2297950
- Korean Circ J.
- 2009 Feb;39(2):57-65.
- doi: 10.4070/kcj.2009.39.2.57
BACKGROUND AND OBJECTIVES: Angiopoietin-1 (Ang1) is a regulator of blood vessel growth and maturation, and prevents radiation-induced or serum deprivation-induced apoptosis. Phosphatase and tensin homologue deleted from chromosome ten (PTEN),... -
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- Angiopoietin-1 variant, COMP-Ang1 attenuates hydrogen peroxide-induced acute lung injury
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Kim SR, Lee KS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Koh GY, Lee YC
- KMID: 756334
- Exp Mol Med.
- 2008 Jun;40(3):320-331.
- doi: 10.3858/emm.2008.40.3.320
Reactive oxygen species (ROS) play a crucial role in acute lung injury. Tissue inflammation, the increased vascular permeability, and plasma exudation are cardinal features of acute lung injury. Angiopoietin-1 (Ang1)... -
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- COMP-Angiopoietin-1 Stimulates Synovial Proliferation but Suppresses Osteoclast by Enhancing Angiogenesis and Osteoblast Maturation in Collagen-Induced Arthritis
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Jeong YG, Kim HO, Lim HS, Hah YS, Cho HY, Yu J, Park BH, Koh GY, Lee SI
- KMID: 2223105
- J Rheum Dis.
- 2012 Apr;19(2):82-90.
- doi: 10.4078/jrd.2012.19.2.82
OBJECTIVE: Angiopoietin-1 (Ang1) is a potent angiogenic factor that can increase synovial angiogenesis and also enhance osteoblast maturation and bone formation. However, its role in rheumatoid arthritis (RA) has not... -
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